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ChemicalBook >> CAS DataBase List >>2,4-Dichloro-5-fluoropyrimidine

2,4-Dichloro-5-fluoropyrimidine

2,4-Dichloro-5-fluoropyrimidine Structure
2,4-Dichloro-5-fluoropyrimidine structure
CAS No.
2927-71-1
Chemical Name:
2,4-Dichloro-5-fluoropyrimidine
Synonyms
5-FLUORO-2,4-DICHLOROPYRIMIDINE;oro-5-fL;NSC 70442;uoropyrimidine;CHEMPACIFIC 37950;Fluorouracil Impurity 9;2,6-DICHLORO-5-FLUORORACIL;2,4-Dichloro-5-fluorouracil;4-Dichloro-5-fluoropyriMidine;2,4-dichloro5-fluropyrimidine
CBNumber:
CB2683700
Molecular Formula:
C4HCl2FN2
Molecular Weight:
166.97
MDL Number:
MFCD00233551
MOL File:
2927-71-1.mol
MSDS File:
SDS
Last updated:2024-08-21 22:41:43
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2,4-Dichloro-5-fluoropyrimidine Properties

Melting point 37-41 °C (lit.)
Boiling point 80 °C / 16mmHg
Density 1.605±0.06 g/cm3(Predicted)
Flash point 223 °F
storage temp. Inert atmosphere,2-8°C
solubility soluble in Chloroform, Methanol
pka -3.96±0.29(Predicted)
form Powder or Crystalline Powder or Low Melting Solid
color White to pale brown
Sensitive Moisture Sensitive
InChI InChI=1S/C4HCl2FN2/c5-3-2(7)1-8-4(6)9-3/h1H
InChIKey WHPFEQUEHBULBW-UHFFFAOYSA-N
SMILES C1(Cl)=NC=C(F)C(Cl)=N1
CAS DataBase Reference 2927-71-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H314
Precautionary statements  P260-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes  Xi,C
Risk Statements  36/37/38-34-22
Safety Statements  26-36-37/39-45-36/37/39
RIDADR  3261
WGK Germany  3
Hazard Note  Irritant
HazardClass  8
PackingGroup  Ⅲ
HS Code  29335990
NFPA 704
1
3 1

2,4-Dichloro-5-fluoropyrimidine price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 653233 2,4-Dichloro-5-fluoropyrimidine 97% 2927-71-1 1g $32.1 2024-03-01 Buy
TCI Chemical D3374 2,4-Dichloro-5-fluoropyrimidine >98.0%(GC) 2927-71-1 5g $20 2024-03-01 Buy
TCI Chemical D3374 2,4-Dichloro-5-fluoropyrimidine >98.0%(GC) 2927-71-1 25g $78 2024-03-01 Buy
Alfa Aesar H26288 5-Fluoro-2,4-dichloropyrimidine, 98% 2927-71-1 5g $58.6 2021-12-16 Buy
Alfa Aesar H26288 5-Fluoro-2,4-dichloropyrimidine, 98% 2927-71-1 1g $21.1 2021-12-16 Buy
Product number Packaging Price Buy
653233 1g $32.1 Buy
D3374 5g $20 Buy
D3374 25g $78 Buy
H26288 5g $58.6 Buy
H26288 1g $21.1 Buy

2,4-Dichloro-5-fluoropyrimidine Chemical Properties,Uses,Production

Chemical Properties

2,4-Dichloro-5-fluoropyrimidine is Yellow to Orange Crystalline Solid

Uses

2,4-Dichloro-5-fluoropyrimidine is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors. It is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors.

Uses

2,4-Dichloro-5-fluoropyrimidine can be used as a starting material to synthesize:

  • 5-fluoropyrimidine-2-carboxamides and 5-fluoropyrimidine-4-carboxamides as potential kinase inhibitors.
  • A series of 2,4-diamino-5-fluoropyrimidine derivatives as potential protein kinase Cθ inhibitors.
  • 2,4-Bisanilinopyrimidine derivatives as potential aurora kinases inhibitors.
  • 5-fluoro-N,N-bis(4-methoxyphenyl)-2,4-pyrimidinediamine by reacting with p-methoxy aniline in the presence of DIPEA.
  • 2-chloro-5-fluoro-4-(4-fluorophenyl)pyrimidine by Suzuki coupling reaction in the presence of (4-fluorophenyl)boronic acid triphenylphosphine, and palladium(II) acetate catalyst.
  • 5-fluoro-2-(piperidin-4-yloxy)pyrimidin-4-amine, a scaffold, which is used in the preparation of potent deoxycytidine kinase inhibitors.

Flammability and Explosibility

Not classified

2,4-Dichloro-5-fluoropyrimidine synthesis

51-21-8
2927-71-1
Synthesis of 2,4-Dichloro-5-fluoropyrimidine from 5-Fluorouracil

2,4-Dichloro-5-fluoropyrimidine Preparation Products And Raw materials

Raw materials

N,N-Dimethylaniline 5-Fluorouracil

Preparation Products

5-Fluorocytosine Pyrimidine, 2-amino-4-chloro-5-fluoro- (7CI,8CI) 1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)- 4-(2-chloro-5-fluoro-pyrimidin-4-yl)-morpholine (2-chloro-5-fluoro-pyrimidin-4-yl)-phenyl-amine
2-Chloro-5-fluoro-4-thiocyanopyrimidine 2-chloro-4-benzyloxy-5-fluoropyrimidine Pyrimidine, 2-chloro-5-fluoro-4-(2-fluoro-4-pyridinyl)- 2-Chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine 2-Chloro-4-ethoxy-5-fluoropyriMidine
6-(2-chloro-5-fluoropyriMidin-4-ylaMino)-2,2-diMethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

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2,4-Dichloro-5-fluoropyrimidine Suppliers

Global( 498)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangsu Guiren Medicine Co.,Ltd
+86-13815020719 +86-13815020719 guiren_medicine@163.com China 133 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5893 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 18779 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
China Synchem Technology Co.,Ltd. 		+86-0552-4929304 +86-18055277008 wangxuhui1985@126.com China 57 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29884 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10310 58
Supplier Advantage
Jiangsu Guiren Medicine Co.,Ltd
58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
China Synchem Technology Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58

View Lastest Price from 2,4-Dichloro-5-fluoropyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-Dichloro-5-fluoropyrimidine pictures 2024-10-11 2,4-Dichloro-5-fluoropyrimidine
2927-71-1
 US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
2,4-Dichloro-5-fluoropyrimidine pictures 2024-04-17 2,4-Dichloro-5-fluoropyrimidine
2927-71-1
 US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
2,4-Dichloro-5-fluoropyrimidine pictures 2022-09-29 2,4-Dichloro-5-fluoropyrimidine
2927-71-1
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

2,4-Dichloro-5-fluoropyrimidine Spectrum

2,4-Dichloro-5-fluoropyrimidine(2927-71-1)1HNMR

2927-71-1(2,4-Dichloro-5-fluoropyrimidine)Related Search:

4-Bromo-2,6-difluorobenzoic acid 2,4-Dichloropyrimidine 5-Fluoropyrimidine Fluorocytosine 2-Chloro-5-fluoropyrimidine
2,4-Dichloro-5-methylpyrimidine Dichlorofluoroethane 4,6-Dichloro-5-fluoropyrimidine FMOC-D-3-Trifluoromethylphe 2-Fluoro-3,5-dichloropyridine
2,4-DICHLORO-6-ETHYL-5-FLUOROPYRIMIDINE 3,5-DICHLORO-4-FLUOROPYRIDINE 2-AMINO-4,6-DICHLORO-5-FLUOROPYRIMIDINE 2,4-DICHLORO-6-FLUOROPYRIMIDINE 2,4,6-TRICHLORO-5-FLUOROPYRIMIDINE
Pyrimidine, 4-chloro-5-fluoro- (9CI) 2,4-Dichloro-5-fluoropyrimidine 2,4-dichloro-5-fluoro-6-methylpyrimidine

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CHEMPACIFIC 37950 2,4-DICHLORO-5-FLUOROPYRIMIDINE 2,4-Dichloro-5-fluorouracil 5-Fluoro-2,4-dichloropyrimdine 2,6-DICHLORO-5-FLUORORACIL 2,4-Dichloro-5-Fluoropyrimidin 2,4-Dichloro-5-fluoropyrimidine99% 2,4-Dichloro-5-fluoropyrimidine ,98% 2,4-Dicloro-5-fluoro pyrimidin 4-Dichloro-5-fluoropyriMidine 2,4-Dichloro-5-fluorpyriMidine 2,4-Dichloro-5-fluoro-1,3-diazine PyriMidine, 2,4-dichloro-5-fluoro- 4-(2-vinyl-1,3-dioxolan-4-yl)butan-1-ol 2,6-Dichloro-5-fluoropyriMidine NSC 70442 2,4-two chloro-5- fluorouracil 5-Fluoro-2,4-dichloropyrimidine,98% Pyrimidine, 5-fluoro-2,4-dichloro- 2,4-Dichloro-5-fluoropyrimidine (Abemaciclib Mesylate) oro-5-fL uoropyrimidine 5-fluoro-2,4-dichloropirimidine 2,4-Dichloro-5-fluoropyrimidine> 2,4-Dichloro-5-fluoropyrimidine ISO 9001：2015 REACH 2,4-dichloro5-fluropyrimidine TIANFU CHEM 2,4-Dichloro-5-fluoropyrimidine 5-FLUORO-2,4-DICHLOROPYRIMIDINE 2,4-Dichloro-5-fluoropyrimidine?New Fluorouracil Impurity 9 2927-71-1 2927-71-7 C4HCl2FN2 C4HCl2FN2O2 C4HCI2FN2 C4HN2Cl2F Building Blocks Heterocyclic Building Blocks Halogenated Heterocycles Pyrimidines Fluorine series Aromatics Bases & Related Reagents Nucleotides Pyrazines, Pyrimidines & Pyridazines Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyrimidines PyrimidinesHeterocyclic Building Blocks Building Blocks Fluorinated Nucleotides and Nucleosides Pyridines, Pyrimidines, Purines and Pteredines pharmacetical Halides Pyrazines, Pyrimidines & Pyridazines Pyrimidine