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PHOLCODINE
- CAS No.
- 509-67-1
- Chemical Name:
- PHOLCODINE
- Synonyms
- (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]morphinan-6-ol;Memine;pha-ol;Codylin;Ethnine;Galphol;pholtex;Dia-tuss;Folkodin;Hibernyl
- CBNumber:
- CB2704131
- Molecular Formula:
- C23H30N2O4
- Molecular Weight:
- 398.5
- MDL Number:
- MFCD00866841
- MOL File:
- 509-67-1.mol
Last updated:2023-05-15 10:44:02
Melting point | 91°C |
---|---|
Boiling point | 521.67°C (rough estimate) |
Density | 1.1772 (rough estimate) |
refractive index | 1.6300 (estimate) |
solubility | Sparingly soluble in water, freely soluble in acetone and in ethanol (96 per cent). It dissolves in dilute mineral acids. |
form | Solid |
pka | pKa 5.30(50% aq EtOH) (Uncertain) |
color | Light Brown |
EWG's Food Scores | 1 |
FDA UNII | LPP64AWZ7L |
ATC code | R05DA08 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264-P270-P301+P312-P330-P501 |
Toxicity | LD50 oral in mouse: 1gm/kg |
PHOLCODINE Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Uses
Antitussive; an opioid cough suppressant. Controlled Substance.
Uses
antimalarial derivative of natural artemisinin
Definition
ChEBI: A morphinane alkaloid that is a derivative of morphine with a 2-morpholinoethyl group at the 3-position.
brand name
Ethnine Simplex (Purdue Frederick).
PHOLCODINE Preparation Products And Raw materials
Raw materials
Preparation Products
509-67-1(PHOLCODINE)Related Search:
PHOLCODINE
ETHYLMORPHINE
PHOLCODINE - REFERENCE SPECTRUM
PHOLCODINE IMP. A (PHARMEUROPA) AS HEMISULPHATE PENTAHEMIHYDRATE: MORPHINE HEMISULPHATE PENTAHEMIHYDRATE[CONTROLLED SUBSTANCE
PHOLCODINE IMP. B (PHARMEUROPA) AS PHOSPHATE HEMIHYDRATE: CODEINE PHOSPHATE HEMIHYDRATE[CONTROLLED SUBSTANCE]
Pholcodine - * narc
PHOLCODINE IMP. A (PHARMEUROPA) AS HYDROCHLORIDE TRIHYDRATE: MORPHINE HYDROCHLORIDE TRIHYDRATE [CONTROLLED SUBSTANCE]
CHEMBRDG-BB 9071306
o-bis(2,3-epoxypropoxy)benzene
Pholcodine for peak identification - * narc
1of4
3-(2-(4-Morpholinyl)ethyl)morphine
3-(2-Morpholinoethyl)morphine
3-Morpholylaethylmorphin
3-o-(2-morpholinoethyl)-morphin
7,8-didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoethoxy)morphinan-6-al
7,8-Didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoethoxy)morphinan-6-alpha-ol
beta-Morpholinoethylmorphine
beta-Morpholinylethylmorphine
Codylin
Dia-tuss
Ethnine
Ethnine Simplex
Folcodine
Folkodin
Galenphol
Galphol
Glycodine
Hibernyl
Homocodeine
Memine
Morphinan-6-alpha-ol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoethoxy)-
tussokon
Weifacodine
PHOLCODINE
O3-(2-morpholinoethyl)morphine
Pholcodine (PI)
(5α,6α)-7,8-Didehydro-4,5-epoxy-17-Methyl-3-[2-(4-Morpholinyl)ethoxy]Morphinan-6-ol
3-O-(2-Morpholinoethyl)Morphine
7,8-Didehydro-4,5α-epoxy-17-Methyl-3-(2-Morpholinoethoxy)Morphinan-6α-ol
Biocalyptol
Folcodin
Neocodine
O-2-MorpholinoethylMorphine
Pholcodine for peak identification
morphinan-6-alpha-ol,7,8-didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoet
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]-, (5alpha,6alpha)-
Morphine, 03-(2-morpholinoethyl)-
Morphine, 3-O-(2-morpholinoethyl)-
Morpholinylethylmorphine
Neocodin
o(sup3)-(2-morpholinoethyl)-morphin
o(sup3)-(2-morpholinoethyl)morphine
O3-(2-Morpholinoethyl)morphine
Pectolin
pha-ol
Pholcodin
pholtex
Prodromine
Tetrahydro-1,4-oxazinylmethylcodeine
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]-, (5α,6α)-
(4R,4aR,7S,7aR,12bS)-3-methyl-9-(2-morpholin-4-ylethoxy)-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol
(5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]morphinan-6-ol
509-67-1
C23H30N2O4
C23H30N2O4H2O
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals