PHOLCODINE
- CAS No.
- 509-67-1
- Chemical Name:
- PHOLCODINE
- Synonyms
- (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]morphinan-6-ol;Memine;pha-ol;Codylin;Ethnine;Galphol;pholtex;Dia-tuss;Folkodin;Hibernyl
- CBNumber:
- CB2704131
- Molecular Formula:
- C23H30N2O4
- Molecular Weight:
- 398.5
- MDL Number:
- MFCD00866841
- MOL File:
- 509-67-1.mol
Melting point | 91°C |
---|---|
Boiling point | 521.67°C (rough estimate) |
Density | 1.1772 (rough estimate) |
refractive index | 1.6300 (estimate) |
solubility | Sparingly soluble in water, freely soluble in acetone and in ethanol (96 per cent). It dissolves in dilute mineral acids. |
form | Solid |
pka | pKa 5.30(50% aq EtOH) (Uncertain) |
color | Light Brown |
EWG's Food Scores | 1 |
FDA UNII | LPP64AWZ7L |
ATC code | R05DA08 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264-P270-P301+P312-P330-P501 |
Toxicity | LD50 oral in mouse: 1gm/kg |
PHOLCODINE Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Uses
Antitussive; an opioid cough suppressant. Controlled Substance.
Uses
antimalarial derivative of natural artemisinin
Definition
ChEBI: A morphinane alkaloid that is a derivative of morphine with a 2-morpholinoethyl group at the 3-position.
brand name
Ethnine Simplex (Purdue Frederick).
PHOLCODINE Preparation Products And Raw materials
Raw materials
Preparation Products
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