4-Acetylbenzoic acid
- CAS No.
- 586-89-0
- Chemical Name:
- 4-Acetylbenzoic acid
- Synonyms
- IBUPROFEN IMP U;RARECHEM AL BO 0065;4-Acetylbenzoci acid;4-ACETYLBENZOIC ACID;4-Acetylbenzoesaeure;4-acetylbenzonic acid;p-Carboxyacetophenone;4-CARBOXYACETOPHENONE;The acetylbenzoic acid;Benzoic acid, 4-acetyl-
- CBNumber:
- CB2704762
- Molecular Formula:
- C9H8O3
- Molecular Weight:
- 164.16
- MDL Number:
- MFCD00002561
- MOL File:
- 586-89-0.mol
- MSDS File:
- SDS
Melting point | 208-210 °C(lit.) |
---|---|
Boiling point | 251.61°C (rough estimate) |
Density | 1.2132 (rough estimate) |
refractive index | 1.5380 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | pK1: 3.70 (25°C) |
form | Crystals or Crystalline Powder |
color | White |
Water Solubility | soluble |
BRN | 2207355 |
InChIKey | QBHDSQZASIBAAI-UHFFFAOYSA-N |
CAS DataBase Reference | 586-89-0(CAS DataBase Reference) |
NIST Chemistry Reference | 4-Acetylbenzoic acid(586-89-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H335-H315-H319 | |||||||||
Precautionary statements | P280g-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38-37/38-36 | |||||||||
Safety Statements | 37/39-26-36-24/25 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 29183000 | |||||||||
NFPA 704 |
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4-Acetylbenzoic acid price More Price(39)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 177458 | 4-Acetylbenzoic acid 98% | 586-89-0 | 1g | $45.4 | 2024-03-01 | Buy |
Sigma-Aldrich | 177458 | 4-Acetylbenzoic acid 98% | 586-89-0 | 10g | $229 | 2024-03-01 | Buy |
TCI Chemical | A1024 | 4-Acetylbenzoic Acid >98.0%(T) | 586-89-0 | 1g | $37 | 2024-03-01 | Buy |
TCI Chemical | A1024 | 4-Acetylbenzoic Acid >98.0%(T) | 586-89-0 | 5g | $104 | 2024-03-01 | Buy |
Alfa Aesar | A15239 | 4-Acetylbenzoic acid, 98+% | 586-89-0 | 1g | $35.65 | 2024-03-01 | Buy |
4-Acetylbenzoic acid Chemical Properties,Uses,Production
Uses
4-Acetylbenzoic Acid is an intermediate used to prepare Curcumin Analogs with anti-oxidant activities. It is also used in the synthesis of quinuclidine benzamides as agonists of α7 nicotinic acetylcholine receptors.
Chemical Properties
White to light yellow crystal powder
Uses
4-Acetylbenzoic acid was used in the preparation of an ester-derivative of paclitaxel.
Synthesis Reference(s)
Synthesis, p. 715, 1974 DOI: 10.1055/s-1974-23412
Purification Methods
4-AcDissolve the acid in 5% aqueous NaOH, extract it with Et2O, and acidify the aqueous solution. Collect the precipitate, and recrystallise it from boiling H2O (100 parts) using decolorising charcoal [Pearson et al. J Org Chem 24 504 1959, Pearson et al. J Chem Soc 265 1957, Detweiler & Amstutz J Am Chem Soc 72 2882 1950, Bordwell & Cooper J Am Chem Soc 74 1058 1952]. [Beilstein 10 IV 2769.]
4-Acetylbenzoic acid Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12495 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21663 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9284 | 55 |
Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 | sales@tjzxchem.com | China | 564 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8820 | 58 |
Chengdu Feibo Pharm Technology Co., Ltd | 15982321820 | abby@arkpharm.com | CHINA | 3279 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from 4-Acetylbenzoic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-08-23 | 4-Acetylbenzoic acid
586-89-0
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | ||
2021-10-15 | 4-Acetylbenzoic acid
586-89-0
|
US $10.00 / KG | 1KG | 99% | 5tons | Hebei Guanlang Biotechnology Co., Ltd. | ||
2019-07-06 | 4-Acetylbenzoic acid
586-89-0
|
US $2.00 / KG | 1KG | 98% | 1ton | Career Henan Chemical Co |
- 4-Acetylbenzoic acid
586-89-0
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
- 4-Acetylbenzoic acid
586-89-0
- US $10.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
- 4-Acetylbenzoic acid
586-89-0
- US $2.00 / KG
- 98%
- Career Henan Chemical Co