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4'-(2-Methylpropyl)acetophenone

4'-(2-Methylpropyl)acetophenone structure

CAS No.: 38861-78-8

Chemical Name:: 4'-(2-Methylpropyl)acetophenone

Synonyms: 1-(4-ISOBUTYLPHENYL)ETHAN-1-ONE;4-ISOBUTYLACETOPHENONE;1-(4-ISOBUTYLPHENYL)ETHANONE;4-IBAP;Nsc173015;1Y1&1R DV1;Ibuprofen-4;IBUPROFEN IMP E;p-Isobutylacetoph;TIMTEC-BB SBB007668

CBNumber:: CB3210390

Molecular Formula:: C12H16O

Molecular Weight:: 176.25

MDL Number:: MFCD00027393

MOL File:: 38861-78-8.mol

Last updated:2025-03-12 18:27:14

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4'-(2-Methylpropyl)acetophenone Properties

Boiling point	134-135°C 16mm
Density	0,952 g/cm³
vapor pressure	0.75Pa at 20℃
refractive index	1.5180
Flash point	54°C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	soluble in Dichloromethane; Diethyl Ether; Ethyl Acetate; THF
form	liquid
color	Colorless to Yellow
Water Solubility	Miscible with chloroform and methanol. Slightly miscible with water.
BRN	1935275
InChI	InChI=1S/C12H16O/c1-9(2)8-11-4-6-12(7-5-11)10(3)13/h4-7,9H,8H2,1-3H3
InChIKey	KEAGRYYGYWZVPC-UHFFFAOYSA-N
SMILES	C(=O)(C1=CC=C(CC(C)C)C=C1)C
LogP	3.4 at 23℃
CAS DataBase Reference	38861-78-8(CAS DataBase Reference)
FDA UNII	AML715RD20
NIST Chemistry Reference	4'-(2-Methylpropyl)acetophenone(38861-78-8)
EPA Substance Registry System	Ethanone, 1-[4-(2-methylpropyl)phenyl]- (38861-78-8)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Signal word

Warning

Hazard statements

H315-H317-H411

Precautionary statements

P261-P264-P272-P273-P280-P302+P352

Hazard Codes

Xn,N,Xi

Risk Statements

10-40-52/53-43

Safety Statements

16-36-22-61-36/37

RIDADR

1224

WGK Germany

TSCA

Yes

HazardClass

3.2

PackingGroup

III

HS Code

29143990

NFPA 704

	2
2		0

4'-(2-Methylpropyl)acetophenone price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR1146	4′-Isobutylacetophenone	38861-78-8	500mg	$128	2024-03-01	Buy
Sigma-Aldrich	BP557	4′-Isobutylacetophenone British Pharmacopoeia (BP) Reference Standard	38861-78-8	100MG	$222	2024-03-01	Buy
Sigma-Aldrich	1335541	Ibuprofen Related Compound C	38861-78-8	3x0.2ml	$1380	2024-03-01	Buy
TCI Chemical	I0417	4'-Isobutylacetophenone >96.0%(GC)	38861-78-8	25mL	$72	2024-03-01	Buy
TCI Chemical	I0417	4'-Isobutylacetophenone >96.0%(GC)	38861-78-8	100mL	$197	2024-03-01	Buy

Product number	Packaging	Price	Buy
PHR1146	500mg	$128	Buy
BP557	100MG	$222	Buy
1335541	3x0.2ml	$1380	Buy
I0417	25mL	$72	Buy
I0417	100mL	$197	Buy

4'-(2-Methylpropyl)acetophenone Chemical Properties,Uses,Production

Chemical Properties

Clear Colourless Oil

Uses

4'-isobutylacetophenone is an important starting material employed in the production of pharmaceuticals such as ibuprofen. It is also utilized in proteomics research. It is used as an intermediate in organic synthesis.

Uses

A degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.

Preparation

Synthesis of 4-isobutylacetophenone: toluene and propylene are reacted with the participation of metal potassium, sodium carbonate and graphite, Alkylation on methyl to generate isobutylbenzene, Then with acetyl chloride in the participation of anhydrous aluminum trichloride to obtain the product.

General Description

4'-(2-Methylpropyl)acetophenone, also known as Ibuprofen EP Impurity E, is an impurity of ibuprofen. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation.

4'-(2-Methylpropyl)acetophenone Preparation Products And Raw materials

Raw materials

Isobutylbenzene Aluminum chloride Potassium Graphite 1-(4-Isobutylphenyl)ethanol

DL-2-(4-Carboxyphenyl)propionic Acid rac a-Hydroxy Ibuprofen 1-Hydroxyibuprofen 4-ISOBUTYLBENZOIC ACID (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID

1-Oxo Ibuprofen 4-Acetylbenzoic acid Ibuprofen

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Preparation Products

4-Isobutylbenzaldehyde

4'-(2-Methylpropyl)acetophenone Suppliers

Global( 372)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Guangzhou Tosun Pharmaceutical Limited	+8618922120635	sales@toref-standards.com	China	998	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531157085	abby@chuanghaibio.com	China	8808	58
Hebei Mujin Biotechnology Co.,Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12809	58
Hebei Mujin Biotechnology Co.,Ltd	+8613288715578	angelia@hbmojin.com	China	750	58
Hebei Yiduo Import and Export Co., Ltd.		joycedemei1505@outlook.com	China	204	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29730	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-+86-371-66670886	info@dakenam.com	China	19805	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21628	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2930	58

Supplier	Advantage
Guangzhou Tosun Pharmaceutical Limited	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Yiduo Import and Export Co., Ltd.	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58

View Lastest Price from 4'-(2-Methylpropyl)acetophenone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-23	4'-(2-Methylpropyl)acetophenone 38861-78-8	US $0.00-0.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-03-21	4'-(2-Methylpropyl)acetophenone 38861-78-8	US $0.00 / kg	1kg	99%	50000KG/month	Hebei Mujin Biotechnology Co.,Ltd
2025-03-21	4'-(2-Methylpropyl)acetophenone 38861-78-8	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mujin Biotechnology Co.,Ltd

4'-(2-Methylpropyl)acetophenone
38861-78-8
US $0.00-0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4'-(2-Methylpropyl)acetophenone
38861-78-8
US $0.00 / kg
99%
Hebei Mujin Biotechnology Co.,Ltd

4'-(2-Methylpropyl)acetophenone
38861-78-8
US $0.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

4'-(2-Methylpropyl)acetophenone Spectrum

4'-(2-Methylpropyl)acetophenone(38861-78-8)MS 4'-(2-Methylpropyl)acetophenone(38861-78-8)¹HNMR 4'-(2-Methylpropyl)acetophenone(38861-78-8)¹³CNMR 4'-(2-Methylpropyl)acetophenone(38861-78-8)IR1

38861-78-8(4'-(2-Methylpropyl)acetophenone)Related Search:

Ibuprofen 1-Hydroxyibuprofen (S)-(+)-Ibuprofen 1-Oxo Ibuprofen Ibuprofen Ethyl Ester

2-[4-(2-Methylpropyl)phenyl] ethanol 6-isobutyl-3-methyl-2,3-dihydro-1H-inden-1-one 2-(4-Methylphenyl)propanoic acid (2RS)-2-(4-BUTYLPHENYL)PROPANOIC ACID rac 2-Hydroxy Ibuprofen

4-(2-Methylpropyl)benzeneethanol (R)-(-)-IBUPROFEN Ibuprofen EP Impurity I 3-(4-ISOBUTYL-PHENYL)-PROPIONIC ACID p-Isobutylstyrene

rac-Ibuprofen amide rac a-Hydroxy Ibuprofen (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID Ibuprofen Impurity E

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Imp. E:1-(4-isobutylphenyl)ethanone TIMTEC-BB SBB007668 P-ISO-BUTYLACETOPHENONE IBUPROFEN IMPURITY E IBUPROFEN IMP E ISOBUTYL ACETOPHENONE 4'-Isobutylacetophenone, 97+% 4'-ISOBUTYLACETOPHENONE 1-[4-(2-METHYLPROPYL)PHENYL]ETHANONE 1-[4-(2-methylpropyl)phenyl]-ethanon 4-Isobutylacetaphenone 1-[4-(2-methylpropyl)phenyl]ethan-1-one 1-(4-(2-METHYLPROPYL)PHENYL)ETNANONE 4'-(2-Methylpropyl)acetophenone 4-lsobutylacetophenone Acetophenone, 4-isobutyl- Ethanone, 1-[4-(2-methylpropyl)phenyl]- Nsc173015 p-Isobutylacetoph Ibuprofen IMpurity-E(EP) 4'-(2-Methylpropyl)a 1-[4-(2-Methylprop-1-yl)phenyl]ethan-1-one, 1-(4-Isobutylphenyl)ethan-1-one Ibuprofen Related CoMpound C, USP 3 ampules) (4-isobutylacetophenone) Ibuprofen Related Compound C (0.2 mL/ampule 1-[4-(2-Methylpropyl)phenyl]-1-ethanone 1-Acetyl-4-isobutylbenzene p-Acetylisobutylbenzene 4-ISOBUTYLACETOPHENONE(Ibuprofen Related Compound C)(Ibuprofen Impurity E) 1Y1&1R DV1 Ibuprofen-4 Ibuprofen EP Impurity E 4-IBAP Ibuprofen USP Related Compound C Ibuprofen EP Impurity E：Ibuprofen Impurity E 4'-Isobutylacetophenone> 4-Isobutylacetophenone（Ibuprofen Impurity） Ibuprofen Impurity 5（Ibuprofen EP Impurity E） Ibuprofen Impurity E/4-isobutylacetophenone Ibuprofen EP Impurity E/ Ibuprofen Related Compound C Ibuprofen USP Related Compound CQ: What is Ibuprofen USP Related Compound C Q: What is the CAS Number of Ibuprofen USP Related Compound C Q: What is the storage condition of Ibuprofen USP Related Compound C Q: What are the applications of Ibuprofen USP Related Compound C 4-ISOBUTYLACETOPHENONE 1-(4-ISOBUTYLPHENYL)ETHAN-1-ONE 1-(4-ISOBUTYLPHENYL)ETHANONE Ibuprofen EP Impurit 4'-Isobutylacetophenone, ≥ 96.0% 4’-Isobutylacetophenone 4''-(2-Methylpropyl)acetophenone 38861-78-8 Aromatic Acetophenones & Derivatives (substituted) Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals Aromatics Impurities Intermediates & Fine Chemicals Pharmaceuticals