4-Bromo-2-fluoroaniline
- CAS No.
- 367-24-8
- Chemical Name:
- 4-Bromo-2-fluoroaniline
- Synonyms
- 2-Fluoro-4-Bromoaniline;4-BROMO-2-FLUORO-PHENYLAMINE;4-Bromo-2-fL;AKOS BBS-00003609;Bromofluoroaniline4;4-Bromo-2-fluoroanil;4-Brom-2-fluoranilin;Fluoro-4-bromoaniline;Vandetanib Impurity 2;4-BROMO-2-FLUOROANILINE
- CBNumber:
- CB2765000
- Molecular Formula:
- C6H5BrFN
- Molecular Weight:
- 190.01
- MDL Number:
- MFCD00010221
- MOL File:
- 367-24-8.mol
- MSDS File:
- SDS
Melting point | 40-42 °C |
---|---|
Boiling point | 103-108 °C (13 mmHg) |
Density | 1.6196 (rough estimate) |
refractive index | 1.4710 (estimate) |
Flash point | 220 °F |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
pka | 2.50±0.10(Predicted) |
form | Crystalline Mass, Powder, Crystals and/or Chunks |
color | Beige to light brown to brown-gray or gray |
BRN | 2081089 |
Stability | Stable. Incompatible with acid chlorides, acid anhydrides, strong acids, strong oxidizing agents. |
InChI | InChI=1S/C6H5BrFN/c7-4-1-2-6(9)5(8)3-4/h1-3H,9H2 |
InChIKey | GZRMNMGWNKSANY-UHFFFAOYSA-N |
SMILES | C1(N)=CC=C(Br)C=C1F |
CAS DataBase Reference | 367-24-8(CAS DataBase Reference) |
NIST Chemistry Reference | 4-Bromo-2-fluoroaniline(367-24-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi,T,Xn | |||||||||
Risk Statements | 36/37/38-20/21/22 | |||||||||
Safety Statements | 26-37/39-36/37/39-36 | |||||||||
RIDADR | UN2811 | |||||||||
WGK Germany | 3 | |||||||||
Hazard Note | Toxic | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29214200 | |||||||||
NFPA 704 |
|
4-Bromo-2-fluoroaniline price More Price(30)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 304220 | 4-Bromo-2-fluoroaniline 98% | 367-24-8 | 10g | $47.2 | 2024-03-01 | Buy |
Sigma-Aldrich | 304220 | 4-Bromo-2-fluoroaniline 98% | 367-24-8 | 50g | $64.2 | 2024-03-01 | Buy |
TCI Chemical | B1314 | 4-Bromo-2-fluoroaniline >98.0%(GC)(T) | 367-24-8 | 25g | $72 | 2024-03-01 | Buy |
Alfa Aesar | A10228 | 4-Bromo-2-fluoroaniline, 98+% | 367-24-8 | 10g | $20.65 | 2024-03-01 | Buy |
Alfa Aesar | A10228 | 4-Bromo-2-fluoroaniline, 98+% | 367-24-8 | 25g | $39.65 | 2024-03-01 | Buy |
4-Bromo-2-fluoroaniline Chemical Properties,Uses,Production
Chemical Properties
solid
Uses
4-Bromo-2-fluoroaniline was used in synthesis of 4-amino-3-fluorophenyl boronic acid. It was also used in chemical modification and synthesis of boronic acid derivatives for ultraviolet-visible titration.
Uses
4-Bromo-2-fluoroaniline can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
Synthesis
To a stirred solution of 4-bromo-2-fluoro-l -nitrobenzene (10 g, 45.5 mmol) in EtOH (50 mL)AVater (20 mL) was added iron (12.7 g, 230 mmol) and NH4C1 (24.3 g, 455 mmol). The reaction mixture was stirred at 90 ??C for 2 h. After 2 h the reaction mixture was filtered over Celite. The filter cake was washed with EtOH (300 mL), and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel chromatography (S1O2, Petroleum ether/EtOAc=10: l to 5: 1) to afford 4-bromo-2-fluoroaniline.
4-Bromo-2-fluoroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Zhejiang Kinso Technology Co., LTD. | +8619857958369 | sales@kinsopharma.com | China | 54 | 58 |
Allfluoro pharmaceutical co. ltd. | 021-26137118 +8615821363818 | sales@allfluoro.com | China | 5791 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3958 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12584 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5894 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20290 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 885 | 50 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
View Lastest Price from 4-Bromo-2-fluoroaniline manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-17 | 4-Bromo-2-fluoroaniline
367-24-8
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | ||
2024-10-17 | 4-Bromo-2-fluoroaniline
367-24-8
|
US $0.00-0.00 / kg | 1kg | 98% | 1 ton | Nanjing Fred Technology Co., Ltd | ||
2024-10-11 | 4-Bromo-2-Fluoroaniline
367-24-8
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
- 4-Bromo-2-fluoroaniline
367-24-8
- US $0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
- 4-Bromo-2-fluoroaniline
367-24-8
- US $0.00-0.00 / kg
- 98%
- Nanjing Fred Technology Co., Ltd
- 4-Bromo-2-Fluoroaniline
367-24-8
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD