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4,4'-OXYBIS(PHENYL ISOCYANATE)

CAS No.
4128-73-8
Chemical Name:
4,4'-OXYBIS(PHENYL ISOCYANATE)
Synonyms
OXYBIS(4-PHENYL ISOCYANATE);4,4'-Oxybis(isocyanatobenzene);4,4'-OXYBIS(PHENYL ISOCYANATE);1,1’-oxybis[4-isocyanato-benzen;4,4'-Bis(isocyanatophenyl)oxide;Oxybis(4-phenyl isocyanate),99%;4,4'-diisocyanatodiphenyl ether;Oxybis(1,4-phenylene)diisocyanate;Benzene, 1,1'-oxybis[4-isocyanato-;Oxybis(1,4-phenylene)bisisocyanate
CBNumber:
CB2772668
Molecular Formula:
C14H8N2O3
Molecular Weight:
252.22
MDL Number:
MFCD00216648
MOL File:
4128-73-8.mol
MSDS File:
SDS
Last updated:2024-12-18 14:08:52

4,4'-OXYBIS(PHENYL ISOCYANATE) Properties

Melting point 64-68 °C(lit.)
Boiling point 196 °C5 mm Hg(lit.)
Density 1.2700 (rough estimate)
refractive index 1.5910 (estimate)
solubility Acetonitrile (Soluble)
form Solid
color White to Off-White
Stability Moisture Sensitive
CAS DataBase Reference 4128-73-8
FDA UNII FY74W1G2FI
EPA Substance Registry System 4,4'-Diisocyanatodiphenyl ether (4128-73-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H312-H315-H317-H319-H330-H334-H335
Precautionary statements  P260-P280-P284-P301+P310-P305+P351+P338-P310
Hazard Codes  Xn,T+
Risk Statements  20/21/22-36/37/38-42/43-26-25-21
Safety Statements  23-26-36/37/39-45-36/37-28-22
RIDADR  UN 2206 6.1/PG 3
WGK Germany  3

4,4'-OXYBIS(PHENYL ISOCYANATE) price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B448770 4,4''-Bis(isocyanatophenyl)oxide 4128-73-8 100mg $55 2021-12-16 Buy
TRC B448770 4,4''-Bis(isocyanatophenyl)oxide 4128-73-8 250mg $110 2021-12-16 Buy
American Custom Chemicals Corporation CHM0138691 4,4'-OXYBIS(PHENYL ISOCYANATE) 96.00% 4128-73-8 5G $886.4 2021-12-16 Buy
Product number Packaging Price Buy
B448770 100mg $55 Buy
B448770 250mg $110 Buy
CHM0138691 5G $886.4 Buy

4,4'-OXYBIS(PHENYL ISOCYANATE) Chemical Properties,Uses,Production

Chemical Properties

WHITE CRYSTALLINE SOLID

Uses

4,4'-Bis(isocyanatophenyl)oxide is a reagent used in the synthesis of lipid-conjugated Smac analogs with antitumor activity against human breast cancer cell lines.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.

Reactivity Profile

Isocyanates and thioisocyanates are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Polyurethanes are formed by the condensation reaction of diisocyanates with, for example, ethyl glycol.

75-44-5
101-80-4
4128-73-8
Synthesis of 4,4'-OXYBIS(PHENYL ISOCYANATE) from PHOSGENE and 4,4'-Oxydianiline

4,4'-OXYBIS(PHENYL ISOCYANATE) Preparation Products And Raw materials

Raw materials

Preparation Products

4,4'-OXYBIS(PHENYL ISOCYANATE) Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24727 58
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42958 64
Jalor-Chem co.,LTD 0510-0510-86396359 13382276200 sales@jalor-chem.com China 997 56
Nanjing crow LuNing pharmaceutical technology co., LTD 13382066392 CHINA 4877 58
BOC Sciences -- info@bocsci.com USA 0 65
TCI (Shanghai) Chemical Trading Co., Ltd. 021-021-61109150 sales@tcisct.com China 31121 58
Shaanxi Dideu Newmaterial Co., Ltd. 029-87576359 15353716720 1039@dideu.com China 10009 58
LGC Science (Shanghai) Ltd. 17717235263 cindy.yang@lgcgroup.com China 15583 58
Hangzhou Bingochem Co., Ltd. 0571-8512-5372 sales@bingochem.com China 21669 58
4008-099-669 23419001name@qq.com CHINA 73043 58
OXYBIS(4-PHENYL ISOCYANATE) 1,1’-oxybis[4-isocyanato-benzen 4,4'-OXYBIS(PHENYL ISOCYANATE) 4,4'-Diisocyanato[1,1'-oxybisbenzene] 4,4'-Oxybis(isocyanatobenzene) Oxybis(1,4-phenylene)bisisocyanate Oxybis(1,4-phenylene)diisocyanate Oxybis(4-phenyl isocyanate),99% 1-isocyanato-4-(4-isocyanatophenoxy)benzene 4,4'-Bis(isocyanatophenyl)oxide Benzene, 1,1'-oxybis[4-isocyanato- 4,4'-diisocyanatodiphenyl ether 4128-73-8 C14H8N2O3 OC6H4NCO2 Building Blocks Organic Building Blocks Nitrogen Compounds Isocyanates Isocyanates Nitrogen Compounds Organic Building Blocks