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Suberic acid

CAS No.
505-48-6
Chemical Name:
Suberic acid
Synonyms
OCTANEDIOIC ACID;suberic;octandioic acid;KORK ACID;CORK ACID;1,8-Octanedioic acid;142-144℃;Suberic aci;SUBERIC ACID;Undecanediol
CBNumber:
CB2775043
Molecular Formula:
C8H14O4
Molecular Weight:
174.19
MDL Number:
MFCD00004428
MOL File:
505-48-6.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

Suberic acid Properties

Melting point 140-144 °C(lit.)
Boiling point 230 °C15 mm Hg(lit.)
Density 1.3010 (rough estimate)
bulk density 700kg/m3
vapor pressure 0Pa at 22.85℃
refractive index 1.4370 (estimate)
Flash point 203 °C
storage temp. Store below +30°C.
solubility 1.6g/l
form Powder
pka 4.52(at 25℃)
color White to cream
PH 3.79(1 mM solution);3.27(10 mM solution);2.76(100 mM solution);
Water Solubility 0.6 g/L (20 ºC)
Merck 14,8862
BRN 1210161
Stability Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, bases.
InChIKey TYFQFVWCELRYAO-UHFFFAOYSA-N
LogP 0.59 at 25℃ and pH7.08
CAS DataBase Reference 505-48-6(CAS DataBase Reference)
FDA UNII 6U7Y4M9C1H
NIST Chemistry Reference Octanedioic acid(505-48-6)
EPA Substance Registry System Octanedioic acid (505-48-6)
UNSPSC Code 12352106
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36-36/37/38
Safety Statements  26-39-36
WGK Germany  1
Autoignition Temperature 430°C
TSCA  Yes
HS Code  29171990
NFPA 704
0
2 0

Suberic acid price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.18800 Octanedioic acid for synthesis 505-48-6 100G $103 2024-03-01 Buy
Sigma-Aldrich 8.18800 Octanedioic acid for synthesis 505-48-6 500G $159 2024-03-01 Buy
Sigma-Aldrich 60930 Suberic acid purum, ≥98.0% (T) 505-48-6 100g $69 2024-03-01 Buy
Sigma-Aldrich 60930 Suberic acid purum, ≥98.0% (T) 505-48-6 1kg $280 2023-06-20 Buy
TCI Chemical O0023 Suberic Acid >99.0%(GC)(T) 505-48-6 25g $19 2024-03-01 Buy
Product number Packaging Price Buy
8.18800 100G $103 Buy
8.18800 500G $159 Buy
60930 100g $69 Buy
60930 1kg $280 Buy
O0023 25g $19 Buy

Suberic acid Chemical Properties,Uses,Production

Description

It was firstly produced by nitric acid oxidation of cork (Latin suber) material and then from castor oil. The oxidation of ricinoleic acid produces, by splitting at the level of the double bond and at the level of the OH group, at the same time, suberic acid (octanedioic acid) and the next homologue azelaic acid. Suberic acid was used in the manufacture of alkyd resins and in the synthesis of polyamides leading to nylon.

Chemical Properties

off-white crystalline powder

Uses

In the plastics industry.

Uses

Suberic Acid is used in the preparation of reduction-sensitive micelles affecting their cellular uptake. This has potential application in delivery of anticancer drugs. It is also used in the fluorescent detection of amidinium-carboxylate and amidinium formation.

Definition

ChEBI: An alpha,omega-dicarboxylic acid that is the 1,6-dicarboxy derivative of hexane.

Reactions

Suberic acid is an essential chemical widespread in softwood trees' trunk. Can there be reactions such as esterification, carboxylic acid halides, amidation and reduction in suberic acid, generation pyrolysis is heated. Its main application is to react with dibasic alcohol and diamine, produce polyester and polymeric amide, and also for organic synthesis.

Synthesis Reference(s)

Journal of the American Chemical Society, 81, p. 3677, 1959 DOI: 10.1021/ja01523a046

Synthesis

Industrial is to be obtained by Viscotrol C or ricinolic acid or cyclooctane oxidation, conventionally using 50% sulfuric acid to carry out catalysis. Suberic acid also can be oxidized and obtained by cyclooctene. A method for preparing suberic acid through cyclooctene oxidation comprises the following steps: mixing tetra-allkylammonium perrhenate and alkyl-imidazolim disulfate ionic liquid in a certain proportion to form a composite phase transfer catalyst and meanwhile carrying out catalytic oxidation reaction on cyclooctene in the presence of alkyl-imidazolim disulfate ionic liquid serving as a reaction solvent and a hydrogen peroxide solution serving as an oxidizing agent, wherein the reaction temperature is 40-70 DEG C, the pressure is normal, and the reaction time is 0.5-4 hours. After the reaction, the gas chromatography detection shows that the conversion rate of the cyclooctene is above 90%, and the cyclooctene yield is above 60%.

Purification Methods

Crystallise it from acetone. It sublimes at 300o without decomposition. [Beilstein 2 IV 2028.]

Toxics Screening Level

The initial threshold screening level (ITSL) for suberic acid is 17 μg/m3 based on an annual averaging time.

Global( 505)Suppliers
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Hebei Weibang Biotechnology Co., Ltd
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Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58

View Lastest Price from Suberic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Suberic acid pictures 2024-11-19 Suberic acid
505-48-6
US $56.00 / g 99.24% 10g TargetMol Chemicals Inc.
Suberic acid pictures 2024-11-14 Suberic acid
505-48-6
US $1.00 / kg 1kg 99% 10 mt Hebei Weibang Biotechnology Co., Ltd
Suberic acid pictures 2023-08-24 Suberic acid
505-48-6
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
  • Suberic acid pictures
  • Suberic acid
    505-48-6
  • US $56.00 / g
  • 99.24%
  • TargetMol Chemicals Inc.
  • Suberic acid pictures
  • Suberic acid
    505-48-6
  • US $1.00 / kg
  • 99%
  • Hebei Weibang Biotechnology Co., Ltd
  • Suberic acid pictures
  • Suberic acid
    505-48-6
  • US $0.00 / KG
  • 99%
  • Hebei Mujin Biotechnology Co.,Ltd
Subericacid,99% 142-144℃ STRYCHNINE (P) Hexane-1,6-dicarboxylic acid, Suberic acid Cork Acid 1,6-Hexanedicarboxylic Acid Kork Acid Octanedioic Acid Suberic aci 1.6-Hexanedica Suberic acid purum, >=98.0% (T) Octanedioic acid for synthesis RARECHEM AL BO 0184 HEXANE-1,6-DICARBOXYLIC ACID DICARBOXYLIC ACID C8 1,6-Dicarboxyhexane 1,8-octanedioicacid Hexamethylenedicarboxylic acid Octane-1,8-dioic acid subericacid(octanedioicacid) 1,6-HEXANEDICARBOXYLIC ACID Oktanedioic acid SUBERIC ACID OCTANEDIOC ACID SubericAcid> suberate (octanedioate) KORK ACID octandioic acid CORK ACID 1,8-Octanedioic acid suberic OCTANEDIOIC ACID Undecanediol Suberic Acid/ 1,6-Hexanedicarboxylic Acid / Octanedioic Acid. Octanedioic acid|||1,8-Octanedioic acid Suberic Acid (Impurity B) Repaglinide Impurity 21 Suberic acid, 10 mM in DMSO 505-48-6 CH26COOH2 HOOCCH26COOH HO2CCH26CO2H Organic Building Blocks Building Blocks C8 Carbonyl Compounds Carboxylic Acids 伪,蠅-Alkanedicarboxylic Acids Monofunctional & 伪,蠅-Bifunctional Alkanes 伪,蠅-Bifunctional Alkanes Pharmaceutical intermediates Dicarboxylic Acids Biochemicals and Reagents Building Blocks C8 Carbonyl Compounds Carboxylic Acids Chemical Synthesis Fatty Acids and conjugates Fatty Acyls Lipids