Desonide
- CAS No.
- 638-94-8
- Chemical Name:
- Desonide
- Synonyms
- Tridesilon;PREDNACINOLONE;d-2083;Topifug;The Ned;DESONIDE;Locapred;Desonade;steroderm;Be Consolide
- CBNumber:
- CB2783466
- Molecular Formula:
- C24H32O6
- Molecular Weight:
- 416.51
- MDL Number:
- MFCD00866151
- MOL File:
- 638-94-8.mol
Melting point | 272-274?C |
---|---|
Boiling point | 580.1±50.0 °C(Predicted) |
Density | 1.30±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | DMF (Slightly, Sonicated), DMSO (Sparingly), Methanol (Slightly, Heated) |
form | Solid |
pka | 12.87±0.10(Predicted) |
color | White to Off-White |
CAS DataBase Reference | 638-94-8(CAS DataBase Reference) |
FDA UNII | J280872D1O |
ATC code | D07AB08,S01BA11 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS08 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H372-H312 | |||||||||
Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P260-P264-P270-P314-P501 | |||||||||
HS Code | 2937290000 | |||||||||
Toxicity | LD50 in rats (mg/kg): 93 s.c. (Phillips) | |||||||||
NFPA 704 |
|
Desonide price More Price(42)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | CDS021596 | Desonide | 638-94-8 | 50MG | $37.8 | 2022-05-15 | Buy |
TCI Chemical | D5578 | Desonide | 638-94-8 | 250MG | $27 | 2024-03-01 | Buy |
TCI Chemical | D5578 | Desonide | 638-94-8 | 1G | $75 | 2024-03-01 | Buy |
Cayman Chemical | 21368 | Desonide ≥98% | 638-94-8 | 50mg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 21368 | Desonide ≥98% | 638-94-8 | 100mg | $176 | 2024-03-01 | Buy |
Desonide Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Originator
Tridesilon,Dome,US,1972
Uses
antifungal
Uses
Desonide(Budesonide EP Impurity F) is an impurity of Budesonide (B689490), an anti-inflammatory.
Uses
Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490).
Indications
Desonide (DesOwen, Tridesilon) is a synthetic corticosteroid.
Definition
ChEBI: Triamcinolone acetonide with hydrogen instead of the fluorine substituent at position 9. A corticosteroid anti-inflammatory, it is used topically as a cream, ointment or lotion for the treatment of various skin disorders.
Manufacturing Process
Preparation of 11β,21-Dihydroxy-16α,17α-Isopropylidenedioxy-1,4- Pregnadiene-3,20-Dione: A solution of 11β,16α,17α,21-tetrahydroxy-1,4- pregnadiene-3,20-dione (40 mg) in acetone (10 ml) containing hydrochloric acid (three drops; d 1.19) is boiled 3n the steam bath for two minutes and then allowed to stand for eighteen hours at room temperature. The reaction mixture is diluted with water (50 ml) and extracted with chloroform (3x25 ml), the combined extracts then being washed with water (30 ml) and dried over anhydrous sodium sulfate. The residue obtained by removal of solvent crystallized from ethyl acetate-petroleum ether as small plates (25 mg), melting point 257°-260°C.
brand name
Desowen (Galderma); Tridesilon (Perrigo).
Therapeutic Function
Antiinflammatory
Desonide Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10986 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1001 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Related articles
- Desonide: Topical Corticosteroid Efficacy and Pharmacokinetics
- Desonide, a nonfluorinated corticosteroid, treats conditions like psoriasis and atopic dermatitis with enhanced absorption in ....
- Nov 29,2024
View Lastest Price from Desonide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-12-13 | Desonide
638-94-8
|
US $0.00 / g | 10g | 97.0-103.0%,USP30 | 50kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-11-19 | Desonide
638-94-8
|
US $40.00 / mg | 99.5% | 10g | TargetMol Chemicals Inc. | |||
2024-11-19 | Desonide
638-94-8
|
US $40.00 / mg | 99.5% | 10g | TargetMol Chemicals Inc. |
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