ChemicalBook >> CAS DataBase List >>ML218 hydrochloride
ML218 hydrochloride
- CAS No.
- 2319922-08-0
- Chemical Name:
- ML218 hydrochloride
- Synonyms
- ML218 hydrochloride,ML-218 hydrochloride
- CBNumber:
- CB28054461
- Molecular Formula:
- C19H27Cl3N2O
- Molecular Weight:
- 405.79
- MDL Number:
- MFCD22683841
- MOL File:
- 2319922-08-0.mol
Last updated:2023-06-30 15:45:59
ML218 hydrochloride Chemical Properties,Uses,Production
Biological Activity
ML 218 hydrochloride is a selective inhibitor of T-type calcium channels (IC50 values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Decreases burst activity in STN neurons; reduces cataleptic behaviour in an in vivo rat model of Parkinson's disease. Displays no significant inhibition of L- or N-type calcium channels, Kir6 (KATP) or KV11.1 (hERG) potassium channels. ML 218 hydrochloride inhibits oral cancer cell proliferation. Orally active.
storage
Store at +4°C
ML218 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
ML218 hydrochloride Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23980 | 58 |
| Shanghai Tachizaki Biomedical Research Center | 18014399201 | sales@chemlab-tachizaki.com | China | 2542 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Aladdin Scientific | 58 |
| TargetMol Chemicals Inc. | 58 |
| Shanghai Tachizaki Biomedical Research Center | 58 |
ML218 hydrochloride,ML-218 hydrochloride
2319922-08-0