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ROR agonist-1

ROR agonist-1 Structure
ROR agonist-1 structure
CAS No.
2361528-74-5
Chemical Name:
ROR agonist-1
Synonyms
ROR agonist-1;ROR agonist1,ROR agonist 1;Benzeneacetamide, α-(acetylamino)-4-(ethylsulfonyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-, (αR)-
CBNumber:
CB28054522
Molecular Formula:
C21H20F6N2O5S
Molecular Weight:
526.45
MDL Number:
MFCD32174299
MOL File:
2361528-74-5.mol
Last updated:2024-10-23 13:36:13
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ROR agonist-1 Properties

Boiling point 743.4±60.0 °C(Predicted)
Density 1.455±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 9.24±0.15(Predicted)

ROR agonist-1 Chemical Properties,Uses,Production

Description

ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5[1]. pIC 50: 7.5 (human primary TH 17 cells)[1]

References

[1]. von Berg S, et al. Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2. ACS Med Chem Lett. 2019 May 29;10(6):972-977.

ROR agonist-1 Preparation Products And Raw materials

Raw materials

Preparation Products

ROR agonist-1 Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32072 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38466 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19863 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19711 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
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View Lastest Price from ROR agonist-1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ROR agonist-1 pictures 2024-10-24 ROR agonist-1
2361528-74-5
 US $2500.00-1520.00 / mg 10g TargetMol Chemicals Inc.
  • ROR agonist-1 pictures
  • ROR agonist-1
    2361528-74-5
  • US $2500.00-1520.00 / mg
  • TargetMol Chemicals Inc.
ROR agonist-1 ROR agonist1,ROR agonist 1 Benzeneacetamide, α-(acetylamino)-4-(ethylsulfonyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-, (αR)- 2361528-74-5