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ChemicalBook >> CAS DataBase List >>2,5-Pyrrolidinedione, 3-amino-, (3S)-

2,5-Pyrrolidinedione, 3-amino-, (3S)-

2,5-Pyrrolidinedione, 3-amino-, (3S)- Structure
2,5-Pyrrolidinedione, 3-amino-, (3S)- structure
CAS No.
73537-92-5
Chemical Name:
2,5-Pyrrolidinedione, 3-amino-, (3S)-
Synonyms
(S)-Aspartimide;(S)-3-Aminopyrrolidine-2,5-dione;2,5-Pyrrolidinedione, 3-amino-, (S)-;2,5-Pyrrolidinedione, 3-amino-, (3S)-
CBNumber:
CB28346717
Molecular Formula:
C4H6N2O2
Molecular Weight:
114.1
MDL Number:
MFCD11894500
MOL File:
73537-92-5.mol
Last updated:2023-04-23 13:52:06
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2,5-Pyrrolidinedione, 3-amino-, (3S)- Properties

Boiling point 337.0±35.0 °C(Predicted)
Density 1.337±0.06 g/cm3(Predicted)
solubility DMSO: soluble; Methanol: soluble
form A solid
pka 8.93±0.50(Predicted)

2,5-Pyrrolidinedione, 3-amino-, (3S)- Chemical Properties,Uses,Production

Description

(S)-Aspartimide is a byproduct formed during solid-phase peptide synthesis (SPPS) of aspartic acid-containing peptides.1 Aspartimide is formed by cyclization of aspartic acid during Fmoc removal or peptide coupling.2

References

1. Ruczyński, J., Lewandowska, B., Mucha, P., et al. Problem of aspartimide formation in Fmoc-based solid-phase peptide synthesis using Dmab group to protect side chain of aspartic acid J. Pept. Sci. 14(3),335-341(2008).
2. Neumann, K., Farnung, J., Baldauf, S., et al. Prevention of aspartimide formation during peptide synthesis using cyanosulfurylides as carboxylic acid-protecting groups Nat. Commun. 11(1),982(2020).

2,5-Pyrrolidinedione, 3-amino-, (3S)- Preparation Products And Raw materials

Raw materials

Preparation Products

2,5-Pyrrolidinedione, 3-amino-, (3S)- Suppliers

Global( 7)Suppliers
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BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
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Supplier Advantage
BOC Sciences 65
Shanghai EFE Biological Technology Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
Bejing Famous Pharmaceutical Technology Co., Ltd. 58
2,5-Pyrrolidinedione, 3-amino-, (3S)- (S)-Aspartimide (S)-3-Aminopyrrolidine-2,5-dione 2,5-Pyrrolidinedione, 3-amino-, (S)- 73537-92-5