ChemicalBook >> CAS DataBase List >>2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride

2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride

CAS No.
35604-67-2
Chemical Name:
2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride
Synonyms
Viloxazine HCl;Viloxazine hydrochloride;Vivalan;Vivilan;Vicilan;Catatrol;Vivarint;ICI-58834;Viloxazin Hydrochloride;Adrenaline Impurity 43-13C6
CBNumber:
CB2933621
Molecular Formula:
C13H20ClNO3
Molecular Weight:
273.7558
MDL Number:
MFCD00661100
MOL File:
35604-67-2.mol
Last updated:2024-04-08 16:27:35

2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride Properties

Melting point 178-180°C
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
FDA UNII OQW30I1332

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
HazardClass  IRRITANT
Toxicity LD50 in mice (mg/kg): 1000 orally, 60 i.v. (Brosnan)

2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC V312440 racViloxazineHydrochloride 35604-67-2 1mg $155 2021-12-16 Buy
TRC V312440 racViloxazineHydrochloride 35604-67-2 10mg $1230 2021-12-16 Buy
Matrix Scientific 058070 2-((2-Ethoxyphenoxy)methyl)morpholinehydrochloride 95% 35604-67-2 500mg $229 2021-12-16 Buy
Matrix Scientific 058070 2-((2-Ethoxyphenoxy)methyl)morpholinehydrochloride 95% 35604-67-2 1g $352 2021-12-16 Buy
American Custom Chemicals Corporation CHM0304667 2-((2-ETHOXYPHENOXY)METHYL)MORPHOLINE HYDROCHLORIDE 95.00% 35604-67-2 5MG $505.68 2021-12-16 Buy
Product number Packaging Price Buy
V312440 1mg $155 Buy
V312440 10mg $1230 Buy
058070 500mg $229 Buy
058070 1g $352 Buy
CHM0304667 5MG $505.68 Buy

2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Originator

Vivalan,I.C.I. ,UK,1974

Uses

Rac Viloxazine Hydrochloride is research useful chemical used as an antidepressant.

Manufacturing Process

2-Ethoxyphenol is first reacted with epichlorohydrin to give 1,2-epoxy-3-(o- ethoxyphenoxy)-propane.
A mixture of crude (83%) 1,2-epoxy-3-(o-ethoxyphenoxy)propane (19.4 grams), 70.5 grams 2-aminoethyl hydrogen sulfate, 40.0 grams sodium hydroxide, 400 ml ethanol and 200 ml water is stirred at 60°C for 18 hours and is then evaporated to dryness. The residue is dissolved in 200 ml water and the mixture is extracted three times with 150 ml of diethyl ether each time. The combined extracts are dried over magnesium sulfate and evaporated to dryness, The crude product (21.5 grams) is dissolved in isopropanol (20 ml), 10.5 ml concentrated aqueous hydrochloric acid and 75 ml ethyl acetate are added and the mixture is cooled. The mixture is filtered and there is thus obtained as solid product 2-(o-ethoxyphenoxymethyl) morpholine hydrochloride, MP 179° to 182°C (8.6 grams; 38% yield based on total epoxide used), according to US Patent 3,712,890.

Therapeutic Function

Psychotropic

94-71-3
35604-67-2
Synthesis of 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride from 2-Ethoxyphenol

2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride Preparation Products And Raw materials

Global( 77)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
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Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
Hubei Jusheng Technology Co.,Ltd.
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CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30240 58
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Wuhan Demeikai Biotechnology Co., Ltd
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GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49979 58
Zhengzhou Lingzhiyue Technology Co., Ltd
+86-0371-55074660 +86-13783527580 Lingzhiyue@aliyun.com China 3145 58

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View Lastest Price from 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride pictures 2024-04-08 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride
35604-67-2
US $8.00-0.80 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
Morpholine, 2-(2-ethoxyphenoxy)methyl-, hydrochloride ICI-58834 Vivalan rac Viloxazine Hydrochloride 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride (+/-)-2-(o-EthoxyphenoxyMethyl)Morpholine Catatrol Vicilan Viloxazin Hydrochloride Vivarint Vivilan Viloxazine hydrochloride Viloxazine HCl Viloxazine hydrochloride salt 2-[(2-Ethoxy phenoxy)methyl]morpholine HCl Adrenaline Impurity 43-13C6 35604-67-2 C13H19NO3HCl Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals