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PEROSPIRONE

PEROSPIRONE Structure
PEROSPIRONE structure
CAS No.
150915-41-6
Chemical Name:
PEROSPIRONE
Synonyms
Perospirine;PEROSPIRONE;PEROSPIRONE HCL;[14C]-Perospirone;PerospironeQ: What is Perospirone Q: What is the CAS Number of Perospirone;cis-N-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]-1,2-cyclohexanedicarboximide;(1R,2S)-N-[4-[4-(1,2-Benzisothiazole-3-yl)-1-piperazinyl]butyl]cyclohexane-1,2-dicarbimide;1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, cis-;(3aα,7aα)-2-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-1H-isoindole-1,3(2H)-dione;(3aR,7aS)-2-[4-[4-(1,2-benzothiazol-3-yl)-1-piperazinyl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione
CBNumber:
CB3101658
Molecular Formula:
C23H30N4O2S
Molecular Weight:
426.57
MDL Number:
MFCD00866669
MOL File:
150915-41-6.mol
MSDS File:
SDS
Last updated:2024-11-19 20:33:22
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PEROSPIRONE Properties

storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
color White to Off-White
FDA UNII N303OK87DT

PEROSPIRONE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P288903 Perospirone 150915-41-6 10mg $90 2021-12-16 Buy
AK Scientific M813 Perospirone 150915-41-6 25mg $95 2021-12-16 Buy
ChemScene CS-0019906 Perospirone 99.51% 150915-41-6 10mg $120 2021-12-16 Buy
American Custom Chemicals Corporation API0008732 PEROSPIRONE 95.00% 150915-41-6 25MG $225.75 2021-12-16 Buy
ChemScene CS-0019906 Perospirone 99.51% 150915-41-6 50mg $420 2021-12-16 Buy
Product number Packaging Price Buy
P288903 10mg $90 Buy
M813 25mg $95 Buy
CS-0019906 10mg $120 Buy
API0008732 25MG $225.75 Buy
CS-0019906 50mg $420 Buy

PEROSPIRONE Chemical Properties,Uses,Production

Description

Perospirone hydrochloride was launched in Japan as a new treatment of schizophrenia and other psychoses. This structurally-related analog of ziprasidone can be classically prepared by alkylation of 1-(3-benzisothiazolyl)-piperazine with the appropriate N- (chlorobutyl)-succinimide. As a result of an in vitro determination of its binding profile, perospirone demonstrated a high affinity for 5-HT2, 5-HT1A and D2 receptors as well as a significant but lower affinity for DI and al receptors. Interestingly, these differential effects on neurotransmitters with a high in vivo occupancy of 5-HT2A receptors with lower D2 occupancy seems to provide this new agent with a significantly lower propensity for the development of extrapyramidal symptoms (EPS) and tardive schizophrenia, the main sideeffects associated with classical antipsychotic therapy. Furthermore, perospirone exhibited anxiolytic-like effects in animal models. A long-term clinical trial (> 6 months) in a group of patients suffering from schizophrenia demonstrated the efficacy of perospirone over placebo for the treatment of the positive, negative and general symptoms of schizophrenia at doses of 12 mg to 96 mg t.i.d.

Originator

Sumitomo Pharm. (Japan)

Definition

ChEBI: (3aR,7aS)-2-[4-[4-(1,2-benzothiazol-3-yl)-1-piperazinyl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione is a N-arylpiperazine.

brand name

Lullan

PEROSPIRONE synthesis

7716-66-7
150915-41-6
Synthesis of PEROSPIRONE from 3-Chloro-1,2-benzisothiazole

PEROSPIRONE Preparation Products And Raw materials

Raw materials

3-Chloro-1,2-benzisothiazole 3-(1-Piperazinyl)-1,2-benzisothiazole

Preparation Products

PEROSPIRONE Suppliers

Global( 59)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739 info@dycnchem.com China 52849 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
PT CHEM GROUP LIMITED 		+86-85511178; +86-85511178; peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49978 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Henan Vcommend Consultrading Co., Ltd. 13393721940; 13393721940 sales@vcommend.com China 10005 58
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10186 62
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
PT CHEM GROUP LIMITED 		58
GIHI CHEMICALS CO.,LIMITED 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Henan Vcommend Consultrading Co., Ltd. 58
Pure Chemistry Scientific Inc. 62

View Lastest Price from PEROSPIRONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Perospirone pictures 2024-11-19 Perospirone
150915-41-6
 US $37.00-113.00 / mg 98.86% 10g TargetMol Chemicals Inc.
  • Perospirone pictures
  • Perospirone
    150915-41-6
  • US $37.00-113.00 / mg
  • 98.86%
  • TargetMol Chemicals Inc.

150915-41-6(PEROSPIRONE)Related Search:

1,2-Cyclohexanedicarboximide 1,2-Cyclohexanedicarboximide etisazole PEROSPIRONE 3-Piperazinobenzisothiazole hydrochloride
PEROSPIRONE HYDROCHLORIDE DIHYDRATE,PEROSPIRONE HYDROCHLORIDE HYDRATE,PEROSPIRONE HYDROCHLORIDE,Perospirone Hydrochloride Trihydrate cis-Octahydroisoindole 1,2-Benzisothiazol-3-amine

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PEROSPIRONE PEROSPIRONE HCL 1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, (3aR,7aS)-rel- (9CI) 1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, cis- cis-N-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]-1,2-cyclohexanedicarboximide Perospirine (1R,2S)-N-[4-[4-(1,2-Benzisothiazole-3-yl)-1-piperazinyl]butyl]cyclohexane-1,2-dicarbimide (3aα,7aα)-2-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-1H-isoindole-1,3(2H)-dione (3aS,7aR)-2-[4-[4-(1,2-Benzothiazol-3-Yl)Piperazin-1-Yl]Butyl]-3a,4,5,6,7,7a-Hexahydroisoindole-1,3-Dione (3aR,7aS)-2-[4-[4-(1,2-benzothiazol-3-yl)-1-piperazinyl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione [14C]-Perospirone 1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, (3aR,7aS)-rel- PerospironeQ: What is Perospirone Q: What is the CAS Number of Perospirone deficits,atypical,Perospirone,SM-9018,Dopamine Receptor,5-hydroxytryptamine Receptor,5-HT Receptor,Orally,SM9018,schizophrenic,disease,Serotonin Receptor,cognitive,Inhibitor,SM 9018,inhibit,antipsychotic 150915-41-6 C23H30N4O2S