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Perospirone hydrochloride

Perospirone hydrochloride Structure
Perospirone hydrochloride structure
CAS No.
129273-38-7
Chemical Name:
Perospirone hydrochloride
Synonyms
Lullan;PEROSPIRONE HYDROCHLORIDE HYDRATE;Lulla;sm-9018;2H8]-Perospirone HCl;SM-9018 hydrochloride;PEROSPIRONE HYDROCHLORIDE;Piropilone (hydrochloride);Perospirone HCl hydrate - Bio-X ?;monohydrochloride,cis-yl)hexahydro
CBNumber:
CB4192563
Molecular Formula:
C23H31ClN4O2S
Molecular Weight:
463.04
MDL Number:
MFCD08457543
MOL File:
129273-38-7.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24
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Perospirone hydrochloride Properties

Melting point 95-970C
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
CAS DataBase Reference 129273-38-7(CAS DataBase Reference)
FDA UNII T884I76TMN
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501

Perospirone hydrochloride price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P288900 PerospironeHydrochlorideHydrate 129273-38-7 1g $1185 2021-12-16 Buy
Matrix Scientific 094175 Perospirone hydrochloride 95+% 129273-38-7 250mg $1418 2021-12-16 Buy
American Custom Chemicals Corporation API0000759 PEROSPIRONE HYDROCHLORIDE TRIHYDRATE 95.00% 129273-38-7 100MG $1732.5 2021-12-16 Buy
American Custom Chemicals Corporation API0000759 PEROSPIRONE HYDROCHLORIDE TRIHYDRATE 95.00% 129273-38-7 250MG $2232.3 2021-12-16 Buy
Biosynth Carbosynth FP65128 Perospirone hydrochloride 129273-38-7 100mg $250 2021-12-16 Buy
Product number Packaging Price Buy
P288900 1g $1185 Buy
094175 250mg $1418 Buy
API0000759 100MG $1732.5 Buy
API0000759 250MG $2232.3 Buy
FP65128 100mg $250 Buy

Perospirone hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Serotonin (5-HT2) and dopamine (D2) antagonist (SDA).

Biological Activity

Perospirone (SM-9018) is a typical neuroleptic (antipsychotic) agent th at displays high affinity for 5-HT2, D2 and 5-HT1A receptors (Ki = 0.61, 1.4 and 2.9-1.8 nM, respectively), moderate affinity for alpha 1 and D1 receptors (Ki = 17 and 41 nM, respectively), while exhibiting much reduced affinity for alpha 2 (Ki = 408 nM) and little affinity toward muscarinic, opiate, glutamate, phencyclidine, benzodiazepine or GABAA receptors (Ki >1 μM). SM-9018 antagonizes both D2-dependent (e.g. methamphetamine-induced hyperactivity, apomorphine-induced stereotypy) and 5-HT2-mediated (e.g. tryptamine-induced clonic seizure) activities in vivo, while exhibiting very low cataleptogenic and central depressant activities commonly observed with two other neuroleptics, haloperidol and chlorpromazine.

IC 50

5-HT2A Receptor: 0.6 nM (Ki); D2 Receptor: 1.4 nM (Ki); 5-HT1A Receptor: 2.9 nM (Ki); 5-HT1 Receptor: 18 nM (Ki); D1 Receptor: 41 nM (Ki)

Perospirone hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Perospirone hydrochloride Suppliers

Global( 195)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21628 55
Hubei XinRunde Chemical Co., Ltd. 		+8615102730682 bruce@xrdchem.cn CHINA 566 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29856 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49732 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17357 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32265 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10244 58
Supplier Advantage
Henan Tianfu Chemical Co.,Ltd. 		55
Hubei XinRunde Chemical Co., Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
SIMAGCHEM CORP 		58
TargetMol Chemicals Inc. 		58
Hubei Ipure Biology Co., Ltd 		58

View Lastest Price from Perospirone hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Perospirone hydrochloride pictures 2025-05-01 Perospirone hydrochloride
129273-38-7
 US $64.00-137.00 / mg 99.37% 10g TargetMol Chemicals Inc.
Perospirone hydrochloride USP/EP/BP pictures 2021-07-24 Perospirone hydrochloride USP/EP/BP
129273-38-7
 US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
Perospirone hydrochloride pictures 2021-07-13 Perospirone hydrochloride
129273-38-7
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

Perospirone hydrochloride Spectrum

Perospirone hydrochloride(129273-38-7)1HNMR

129273-38-7(Perospirone hydrochloride)Related Search:

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Cyhalofop-butyl 2-Butoxyethanol PEROSPIRONE 2,2'-Dithiobis(benzothiazole) 2-Mercaptobenzothiazole
BUTYL OLEATE Butyl acrylate Butyl acetate

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PEROSPIRONE HYDROCHLORIDE PEROSPIRONE HYDROCHLORIDE DIHYDRATE 1h-isoindole-1,3(2h)-dione,2-(4-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)but monohydrochloride,cis-yl)hexahydro sm-9018 (3aR,7aS)-rel-2-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-1H- isoindole-1,3(2H)-dione Hydrochloride Trihydrate Lulla Perospirone Hydrochloride Trihydrate (3ar,7as)-2-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione hydrochloride SM-9018 hydrochloride (3aR,7aS)-2-(4-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)butyl)hexahydro-1H-isoindole-1,3(2H)-dione hydrochloride 1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, hydrochloride (1:1), (3aR,7aS)-rel- Perospirone hydrochloride USP/EP/BP Lullan PEROSPIRONE HYDROCHLORIDE HYDRATE 2H8]-Perospirone HCl Piropilone (hydrochloride) Perospirone hydrochloride, 10 mM in DMSO Perospirone HCl hydrate - Bio-X ? 129273-38-7 12973-38-7 C23H37ClN4O5S C23H30N4O2SHCl C23H30N4O2SHCl2H2O C24H33ClN4O2S Intermediates & Fine Chemicals Pharmaceuticals