ChemicalBook >> CAS DataBase List >>Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]-
Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]-
- CAS No.
- 1454902-97-6
- Chemical Name:
- Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]-
- Synonyms
- Elevenostat;N-hydroxy-4-((3-(2-methoxyphenyl)ureido)methyl)benzamide;Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]-;Histone deacetylases,Elevenostat,JB3-22,multiple myeloma,inhibit,HDAC11,Inhibitor,HDAC
- CBNumber:
- CB310614294
- Molecular Formula:
- C16H17N3O4
- Molecular Weight:
- 315.32
- MDL Number:
- MOL File:
- 1454902-97-6.mol
Last updated:2024-07-02 08:55:04
Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- Chemical Properties,Uses,Production
Biological Activity
Elevenostat (JB3-22) is a selective HDAC11 inhibitor (IC50=0.235 μM). Anti-multiple myeloma (MM) activity[1].
References
[1]. Huang J, et al. Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function. Sci Rep. 2017;7(1):8626. Published 2017 Aug 17. [2]. Mostofa A, et al. Plasma cell dependence on histone/protein deacetylase 11 reveals a therapeutic target in multiple myeloma. JCI Insight. 2021;6(24):e151713. Published 2021 Dec 22.
Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- Suppliers
Global( 14)Suppliers
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Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | sales@tybiochem.com | China | 5587 | 58 |
Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]-
N-hydroxy-4-((3-(2-methoxyphenyl)ureido)methyl)benzamide
Elevenostat
Histone deacetylases,Elevenostat,JB3-22,multiple myeloma,inhibit,HDAC11,Inhibitor,HDAC
1454902-97-6