a-Hydroxy Tamoxifen
- CAS No.
- 97151-02-5
- Chemical Name:
- a-Hydroxy Tamoxifen
- Synonyms
- α-OHTAM;α-OHTAM;α-hydroxy Tamoxifen;(E)-α-Hydroxy tamoxifen;(E)-α-Hydroxy Tamoxifen;(E)-(+/-)-alpha-Hydroxytamoxifen;Benzeneethanol,b-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-a-methyl-,(bE)-;Benzeneethanol, β-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-α-methyl-, (βE)-
- CBNumber:
- CB31176114
- Molecular Formula:
- C26H29NO2
- Molecular Weight:
- 387.52
- MDL Number:
- MFCD02101152
- MOL File:
- 97151-02-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H361 | |||||||||
| Precautionary statements | P201-P202-P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P304+P340-P308+P313-P321-P362+P364-P405-P501 | |||||||||
| NFPA 704 |
|
a-Hydroxy Tamoxifen price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17204 | α-hydroxy Tamoxifen ≥98% | 97151-02-5 | 500μg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 17204 | α-hydroxy Tamoxifen ≥98% | 97151-02-5 | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 17204 | α-hydroxy Tamoxifen ≥98% | 97151-02-5 | 5mg | $214 | 2024-03-01 | Buy |
| Cayman Chemical | 17204 | α-hydroxy Tamoxifen ≥98% | 97151-02-5 | 10mg | $335 | 2024-03-01 | Buy |
| TRC | H954700 | (E)-α-HydroxyTamoxifen | 97151-02-5 | 10mg | $145 | 2021-12-16 | Buy |
a-Hydroxy Tamoxifen Chemical Properties,Uses,Production
Description
Tamoxifen is a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. Although it is an antagonist of ER action in breast tissue, it acts as an ER agonist in bone and blood vessels and a partial ER agonist in uterine tissues. α-hydroxy Tamoxifen is a reactive metabolite of tamoxifen that is formed by the action of cytochrome P450 3A4 in human liver. It can be further converted into genotoxic DNA adducts though a mechanism involving reversible O-sulfonation of the hydroxyl moiety, which in rats has been linked with hepatocarcinoma.
Chemical Properties
Pale Yellow Solid
Uses
A metabolite of the chemotherapeutic drug Tamoxifen (T006000). Exhibits a more potent estrogen agonist/antagonist activity than the parent drug. Also active as an intramembranous inhibitor of lipid peroxidation.
Uses
A metabolite of the chemotherapeutic drug tamoxifen. Exhibits a more potent estrogen agonist/antagonist activity than the parent drug. Also active as an intramembranous inhibitor of lipid peroxidation.
Definition
ChEBI: Alpha-Hydroxytamoxifen is a stilbenoid.
a-Hydroxy Tamoxifen Preparation Products And Raw materials
Raw materials
Preparation Products
a-Hydroxy Tamoxifen Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94717 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 56070 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |