ANTI-CALPASTATIN
- CAS No.
- Chemical Name:
- ANTI-CALPASTATIN
- Synonyms
- Anti-BS-17;Anti-MGC9402;ANTI-CALPASTATIN;Anti-Calpain inhibitor;ANTI-CALPASTATIN, HUMAN;ANTI-CALPASTATIN MOUSE MAB;Anti-Calpastatin isoform a;ANTI-CALPASTATIN (DOMAIN IV);ANTI-CALPASTATIN (DOMAIN II);ANTI-CALPASTATIN, HUMAN (MOUSE)
- CBNumber:
- CB3143962
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00164555
- MOL File:
- Mol file
ANTI-CALPASTATIN price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C270 | Monoclonal Anti-Calpastatin antibody produced in mouse clone 1F7E3D10, ascites fluid, buffered aqueous solution | 100μL | $581 | 2024-03-01 | Buy | |
| American Custom Chemicals Corporation | ATB0010642 | ANTI-CALPASTATIN 95.00% | 5MG | $495.36 | 2021-12-16 | Buy |
ANTI-CALPASTATIN Chemical Properties,Uses,Production
Uses
Monoclonal Anti-Calpastatin antibody produced in mouse is suitable for indirect immunofluorescence at a dilution of 1:200 and for western blotting at a dilution of 1:5,000.
General Description
Calpastatin is a protein encoded by the CAST gene in humans. Calpastatin is an endogenous inhibitor of the ubiquitous calcium dependent proteinases μ- and m-calpain. It plays a key role in many cellular physiological and pathological processes. Calpastatin level is very important for controlling calpain activity.
Biochem/physiol Actions
Calpastatin availability in cytosol is controlled by Ca2+ and cyclic AMP. Prolonged calpain activation promotes degradation of calpastatin. Calpastatin is found to be overexpressed in mycoplasma-contaminated cultured cells. CAST gene is found to be involved in genetic susceptibility to Keratoconus (KC), a genetically heterogeneous corneal dystrophy. It is also found to be associated with Parkinson′s disease (PD) and single nucleotide polymorphisms (SNPs).
ANTI-CALPASTATIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-CALPASTATIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai guandao biology engineering co., ltd | 18818239863 18818239863 | 3171921642@qq.com | China | 8889 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Shanghai guandao biology engineering co., ltd | 58 |