1-Adamantanecarboxylic acid
- CAS No.
- 828-51-3
- Chemical Name:
- 1-Adamantanecarboxylic acid
- Synonyms
- ADAMANTANE-1-CARBOXYLIC ACID;1-Adamantyl Carboxylic Acid;Adamantoic acid;1-AdamantanecarboxyL;adamantanecarboxylic acid;1-Adamantanecarboxylic;Adamantane-1-carboxylic acid 99%;Saxaint-K;AKOS BC-0655;1-ADAMANTOIC ACID
- CBNumber:
- CB3145173
- Molecular Formula:
- C11H16O2
- Molecular Weight:
- 180.24
- MDL Number:
- MFCD00074720
- MOL File:
- 828-51-3.mol
- MSDS File:
- SDS
| Melting point | 172-174 °C (lit.) |
|---|---|
| Boiling point | 253.08°C (rough estimate) |
| Density | 0.9976 (rough estimate) |
| refractive index | 1.4910 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 4.86±0.20(Predicted) |
| color | White to off-white |
| Water Solubility | Insoluble in water. Solubility in methanol gives very faint turbidity. Soluble in ethanol, chloroform, and dichloromethane. |
| BRN | 1910637 |
| InChI | InChI=1S/C11H16O2/c12-10(13)11-4-7-1-8(5-11)3-9(2-7)6-11/h7-9H,1-6H2,(H,12,13) |
| InChIKey | JIMXXGFJRDUSRO-UHFFFAOYSA-N |
| SMILES | C12(C(O)=O)CC3CC(CC(C3)C1)C2 |
| CAS DataBase Reference | 828-51-3(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NIST Chemistry Reference | Adamantane-1-carboxylic acid(828-51-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AU4452200 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29162000 | |||||||||
| NFPA 704 |
|
1-Adamantanecarboxylic acid price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 106399 | 1-Adamantanecarboxylic acid 99% | 828-51-3 | 25g | $71.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | 106399 | 1-Adamantanecarboxylic acid 99% | 828-51-3 | 100g | $114 | 2024-03-01 | Buy |
| TCI Chemical | A0742 | 1-Adamantanecarboxylic Acid >98.0%(GC)(T) | 828-51-3 | 25g | $26 | 2024-03-01 | Buy |
| TCI Chemical | A0742 | 1-Adamantanecarboxylic Acid >98.0%(GC)(T) | 828-51-3 | 100g | $75 | 2024-03-01 | Buy |
| Alfa Aesar | A12959 | Adamantane-1-carboxylic acid, 99% | 828-51-3 | 25g | $59.65 | 2024-03-01 | Buy |
1-Adamantanecarboxylic acid Chemical Properties,Uses,Production
Chemical Properties
white to off-white crystalline powder
Uses
1-Adamantanecarboxylic acid can be used as:
- A stabilizer in the synthesis of monodisperse, highly crystalline CoPt3?nanoparticles and porous platinum nanoparticles.
- An additive in polycondensation reactions to yield conjugated polymers as possible optoelectronic materials.
- An additive in the allylic substitution reaction, which is catalyzed by palladium in an aqueous medium.
Uses
It can be used as a stabilizer in the synthesis of monodisperse, highly crystalline CoPt3 nanoparticles1 and porous platinum nanoparticles. It is a potent and reversible CerK inhibitor.
Uses
Adamantoic Acid is an inhibitor of chorismate mutase activity and hydroxyphenylpyruvate synthase. It inhibits TTR conformational changes facilitating amyloid fibril formation.
Synthesis Reference(s)
Synthetic Communications, 18, p. 545, 1988 DOI: 10.1080/00397918808060749
Biochem/physiol Actions
1-Adamantanecarboxylic acid undergoes complexation reactions with cyclohexaamylose. It is an inhibitor of phenyl ester hydrolysis of cycloheptaamylose.
Purification Methods
Possible impurities are trimethylacetic acid and C9 and C13 acids. Dissolve 15g of the acid in CCl4 (300mL) and shake with 110mL of 15N aqueous NH3 whereby the ammonium salt separates and is collected. Acid impurities form soluble ammonium salts. The salt is washed with cold Me2CO (20mL) and suspended in H2O (250mL). This is treated with 12N HCl and extracted with CHCl3 (100mL). The dried (Na2SO4) extract was evaporated and the residue was recrystallised from a mixture of MeOH (30mL) and H2O (ca 10mL) to give the pure acid (10-11g). [Koch & Haaf Org Synth Coll Vol V 20 1973.] It was also recrystallised from absolute EtOH and dried under vacuum at 100o. Alternatively, the acid (5g) is refluxed for 2hours with 15mL of MeOH and 2mL of 98% H2SO4 (cool when mixing this solution). Pour into 10 volumes of H2O and extract with the minimum volume of CHCl3 to give clear separation of phases. The extract is washed with H2O, dried (CaCl2) and distilled. The methyl ester is collected at 77-79o/1mm, m 38-39o. The ester is hydrolysed with the calculated amount of N KOH and refluxed until clear. Acidification with HCl provides the pure acid with 90% recovery. The amide crystallises from cyclohexane, m 189o. [Stetter et al. Chem Ber 92 1629 1959.] [Beilstein 9 IV 253.]
1-Adamantanecarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Huzhou Chenxi Environmental Protection Technology Co. , Ltd. | +8616762203950 | 1034385273@qq.com | China | 55 | 58 |
| Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 | info@allgreenchem.com | China | 5983 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8812 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
| Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | clara@hbshengyang.com | China | 874 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019 +86-15383190639 | admin@86-ss.com | China | 1000 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18779 | 58 |
View Lastest Price from 1-Adamantanecarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-22 | 1-Adamantanecarboxylic acid
828-51-3
|
US $99.00-66.00 / kg | 0.001kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2024-11-22 | 1-Adamantanecarboxylic acid
828-51-3
|
US $100.00 / kg | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-11-14 | 1-Adamantanecarboxylic acid
828-51-3
|
US $1.00 / kg | 1kg | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd |
-
- 1-Adamantanecarboxylic acid
828-51-3
- US $99.00-66.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 1-Adamantanecarboxylic acid
828-51-3
- US $100.00 / kg
- 99
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- 1-Adamantanecarboxylic acid
828-51-3
- US $1.00 / kg
- 99%
- Hebei Weibang Biotechnology Co., Ltd
1-Adamantanecarboxylic acid Spectrum
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