4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid
- CAS No.
- 216167-82-7
- Chemical Name:
- 4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid
- Synonyms
- AGZ-1067;AGI 1067;SUCCINOBUCOL;Flunixin Monomer;SUCCINOBUCOL, >98%;Probucol Monosuccinate;Succinobucol(AGI 1067);Succinobucol, 10 mM in DMSO;Probucol monosuccinate, >98%;AGZ1067. Probucol monosuccinae
- CBNumber:
- CB31458896
- Molecular Formula:
- C35H52O5S2
- Molecular Weight:
- 616.91
- MDL Number:
- MFCD08690469
- MOL File:
- 216167-82-7.mol
- MSDS File:
- SDS
4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Properties
Melting point | 139 - 142°C |
---|---|
Boiling point | 659.5±55.0 °C(Predicted) |
Density | 1.13±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
pka | 4.27±0.17(Predicted) |
form | Solid |
color | White to Light Yellow |
FDA UNII | J1J54V24R4 |
UNSPSC Code | 12352200 |
NACRES | NA.77 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid price More Price(12)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | S688775 | Succinobucol | 216167-82-7 | 25mg | $135 | 2021-12-16 | Buy |
TRC | S688775 | Succinobucol | 216167-82-7 | 50mg | $175 | 2021-12-16 | Buy |
TRC | S688775 | Succinobucol | 216167-82-7 | 100mg | $320 | 2021-12-16 | Buy |
Usbiological | 289222 | Succinobucol | 216167-82-7 | 25mg | $460 | 2021-12-16 | Buy |
TRC | S688775 | Succinobucol | 216167-82-7 | 250mg | $790 | 2021-12-16 | Buy |
4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Chemical Properties,Uses,Production
Uses
An antioxidant and anti-inflammatory.
Definition
ChEBI: Succinobucol is a benzoate ester and a member of phenols.
Biological Activity
Succinobucol is a metabolically stable derivative of the antioxidant drug probucol th at poses a distinct pharmacological from. Succinobucol is an orally active vascular protectant th at exhibits antiatherosclerotic properties in multiple animal models and in humans. It inhibits the release of proinflammatory cytokines, TNF-a, IL-1b, and IL-6 in hPBMC activated by LPS.
in vivo
Succinobucol (50, 100, and 150 mg/kg, i.v.) has no significant effect on either heart rate or MAP, but the blood removed 15 minutes after the final injection of succinobucol shows significantly less aggregation in response to collagen at both 5 μg/mL and 20 μg/mL in rats[1]. Succinobucol (40 mg/kg) by tail injection significantly reduces the average number of metastatic nodules in lung metastatic breast cancer mice[3].
4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
Shochem(Shanghai) Co.,Ltd | 86-21-50800795 | info@shochem.com | CHINA | 288 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
DAYANG CHEM (HANGZHOU) CO.,LTD | +8617705817739 | info@dycnchem.com | China | 53881 | 58 |
View Lastest Price from 4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-11-19 | Succinobucol
216167-82-7
|
US $30.00-98.00 / mg | 99.96% | 10g | TargetMol Chemicals Inc. |
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- Succinobucol
216167-82-7
- US $30.00-98.00 / mg
- 99.96%
- TargetMol Chemicals Inc.