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3,4-Dimethoxy-3-cyclobutene-1,2-dione

CAS No.
5222-73-1
Chemical Name:
3,4-Dimethoxy-3-cyclobutene-1,2-dione
Synonyms
3,4-DIMETHOXYCYCLOBUT-3-ENE-1,2-DIONE;DIMETHYL SQUARATE;diMethoxycyclobut-3-ene-1,2-dione;3,4-Dimethoxy-3-cycl;Squaric acid dimethyl e;SQUARIC ACID DIMETHYL ESTER;3,4-DIMETHOXYCYCLOBUTANE-1,2-DIONE;1,2-Dimethoxycyclobutene-3,4-dione;1,2-Dimethoxy-1-cyclobutene-3,4-dione;3,4-DIMETHOXY-3-CYCLOBUTENE-1,2-DIONE
CBNumber:
CB3165164
Molecular Formula:
C6H6O4
Molecular Weight:
142.11
MDL Number:
MFCD00101316
MOL File:
5222-73-1.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

3,4-Dimethoxy-3-cyclobutene-1,2-dione Properties

Melting point 55-57 °C (lit.)
Boiling point 219.65°C (rough estimate)
Density 1.3863 (rough estimate)
refractive index 1.5800 (estimate)
storage temp. 2-8°C
solubility DMSO, Methanol (Slightly)
form Solid
color Off-White to Pale Brown
Water Solubility Very soluble in water.
InChIKey SZBNZTGCAMLMJY-UHFFFAOYSA-N
CAS DataBase Reference 5222-73-1(CAS DataBase Reference)
NIST Chemistry Reference 3,4-Dimethoxy-3-cyclobutene-1,2-dione(5222-73-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H317-H334
Precautionary statements  P261-P280-P342+P311
Risk Statements  42/43
Safety Statements  22-24/25-26-36/37/39
WGK Germany  3
HS Code  29145090
NFPA 704
1
2 0

3,4-Dimethoxy-3-cyclobutene-1,2-dione price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 377406 3,4-Dimethoxy-3-cyclobutene-1,2-dione 99% 5222-73-1 1g $16.5 2024-03-01 Buy
Sigma-Aldrich 377406 3,4-Dimethoxy-3-cyclobutene-1,2-dione 99% 5222-73-1 5g $104 2024-03-01 Buy
TCI Chemical D2099 3,4-Dimethoxy-3-cyclobutene-1,2-dione >98.0%(GC) 5222-73-1 1g $44 2024-03-01 Buy
TCI Chemical D2099 3,4-Dimethoxy-3-cyclobutene-1,2-dione >98.0%(GC) 5222-73-1 5g $134 2024-03-01 Buy
Alfa Aesar A18186 3,4-Dimethoxy-3-cyclobutene-1,2-dione, 98% 5222-73-1 1g $50.65 2024-03-01 Buy
Product number Packaging Price Buy
377406 1g $16.5 Buy
377406 5g $104 Buy
D2099 1g $44 Buy
D2099 5g $134 Buy
A18186 1g $50.65 Buy

3,4-Dimethoxy-3-cyclobutene-1,2-dione Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

3,4-Dimethoxy-3-cyclobutene-1,2-dione (Dimethyl squarate) finds it uses in the synthesis of chiral squaramides, highly enantioselective catalyst for the Friedel-Crafts reactions of indoles, 3-(hydroxyamino)-4-methoxy-3-cyclobutene-1,2-dione, squarate derivatives of the O-SP-core antigens, methyl squarate derivative of the Ogawa O-SP-core antigen, o-quinodimethanes, benzocyclobutenes, quinones. It is employed as a starting material in the preparation of o-quinodimethanes, benzocyclobutenes, and quinones.

General Description

3,4-Dimethoxy-3-cyclobutene-1,2-dione (Dimethyl squarate) is a cyclobutene derivative. It reacts with hydroxylamine derivatives to afford 3-hydroxyamino-4-methoxy-3-cyclobutene-1,2-diones.

67-56-1
2892-51-5
5222-73-1
Synthesis of 3,4-Dimethoxy-3-cyclobutene-1,2-dione from Methanol and Squaric acid
Global( 213)Suppliers
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Capot Chemical Co.,Ltd.
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Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
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View Lastest Price from 3,4-Dimethoxy-3-cyclobutene-1,2-dione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,4-Dimethoxy-3-cyclobutene-1,2-dione pictures 2024-11-29 3,4-Dimethoxy-3-cyclobutene-1,2-dione
5222-73-1
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
3,4-Dimethoxy-3-cyclobutene-1,2-dione pictures 2022-09-20 3,4-Dimethoxy-3-cyclobutene-1,2-dione
5222-73-1
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
3,4-Dimethoxy-3-cyclobutene-1,2-dione pictures 2019-07-06 3,4-Dimethoxy-3-cyclobutene-1,2-dione
5222-73-1
US $7.00 / kg 1kg 99% 100kg Career Henan Chemical Co
3-Cyclobutene-1,2-dione,3,4-dimethoxy- 3,4-Dimethoxycyclobut-3-ene-1,2-dione 98% Dimethyl squarate, 1,2-Dimethoxy-3,4-dioxocyclobut-1-ene Dimethyl squarate 3,4-Dimethoxy-3-cyclobutene-1,2-dione SQUARIC ACID DIMETHYL ESTER 3,4-DIMETHOXY-3-CYCLOBUTENE-1,2-DIONE Squaric acid dimethyl ester,(Dimethyl squarate, 3,4-Dimethoxy-3-cyclobutene-1,2-dione) 3,4-DIMETHOXYCYCLOBUTANE-1,2-DIONE Dimethyl squarate, Squaric acid dimethyl ester 1,2-Dimethoxy-1-cyclobutene-3,4-dione 1,2-Dimethoxycyclobutene-3,4-dione 3,4-DIMETHOXY-3-CYCLOBUTENE-1,2-DIONE, 9 9% 3,4-Dimethoxy-3-cycl 3.4-diMethoxycyclobutane-1.2-dione. DiMethyl squarate Squaric acid dimethyl e 8,9-dimethoxy-2-[[2-(4-morpholinyl)ethylamino]-oxomethyl]-5,6-dihydropyrrolo[2,1-a]isoquinoline-3-carboxylic acid 3,4-Dimethoxy-3-cyclobutene-1,2-dione> DIMETHYL SQUARATE diMethoxycyclobut-3-ene-1,2-dione 3,4-DIMETHOXYCYCLOBUT-3-ENE-1,2-DIONE 5222-73-1 CH3O2C4O2 C6H6O4 Ketones Organic Building Blocks C3 to C6 Simple 4-Membered Ring Compounds Cyclobutanes & Cyclobutenes Carbonyl Compounds Building Blocks Cyclobutanes & Cyclobutenes Simple 4-Membered Ring Compounds Ring Systems Aluminium foil bag/Fluoride bottle or on your request Pyrimidines