ChemicalBook >> CAS DataBase List >>5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE

5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE

CAS No.
524-81-2
Chemical Name:
5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE
Synonyms
Mebhydrin.;MEBHYDROLIN;Mebhydroline;Mebhydrolin, 10 mM in DMSO;N-Methyl-9-benzyltetrahydro-γ-carboline;Mebhydrolin,inhibit,Histamine Receptor,Inhibitor;3-Benzyl-6-methyl-1,2,3,4-tetrahydro-gamma-carboline;5-benzyl-2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indole;5-benzyl-1,2,3,4-tetrahydro-2-methylpyrido(4,3-b)indole;5-Benzyl-1,3,4,5-tetrahydro-2-methyl-2H-pyrido[4,3-b]indole
CBNumber:
CB3167173
Molecular Formula:
C19H20N2
Molecular Weight:
276.38
MDL Number:
MFCD00865679
MOL File:
524-81-2.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:03

5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE Properties

Melting point 95°
Boiling point bp1 207-215°
Density 1.0246 (rough estimate)
refractive index 1.5640 (estimate)
storage temp. Store at -20°C
solubility DMSO : 83.33 mg/mL (301.51 mM)
form Solid
pka pKa 2.55 ± 0.18;7.63± 0.04(H2O,t undefined,I=0.30(NaCl)) (Uncertain)
color White to off-white
FDA UNII 9SUK9B7XVY
ATC code R06AX15

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B535318 5-Benzyl-2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indole 524-81-2 10mg $45 2021-12-16 Buy
ChemScene CS-0013654 Mebhydrolin 99.58% 524-81-2 100mg $70 2021-12-16 Buy
American Custom Chemicals Corporation CHM0027089 MEBHYDROLIN 95.00% 524-81-2 1G $765.23 2021-12-16 Buy
American Custom Chemicals Corporation CHM0027089 MEBHYDROLIN 95.00% 524-81-2 2.5G $1065.66 2021-12-16 Buy
American Custom Chemicals Corporation CHM0027089 MEBHYDROLIN 95.00% 524-81-2 5G $1295.03 2021-12-16 Buy
Product number Packaging Price Buy
B535318 10mg $45 Buy
CS-0013654 100mg $70 Buy
CHM0027089 1G $765.23 Buy
CHM0027089 2.5G $1065.66 Buy
CHM0027089 5G $1295.03 Buy

5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE Chemical Properties,Uses,Production

Uses

Mebhydrolin is a specific histamine H1 receptor antagonist.

Definition

ChEBI: Mebhydrolin is a member of indoles.

References

[1] O'Neill PA, et al. Chlorpromazine-a specific effect on breathlessness? Br J Clin Pharmacol. 1985 Jun;19(6):793-7. DOI:10.1111/j.1365-2125.1985.tb02716.x
[2] Franks HM, et al. Interaction between ethanol and antihistamines: 3. Mebhydrolin. Med J Aust. 1981 Oct 31;2(9):477-9. DOI:10.5694/j.1326-5377.1981.tb112944.x

34737-83-2
614-31-3
524-81-2
Synthesis of 5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE from 1-Methyl-4-piperidinol hydrochloride and 1-BENZYL-1-PHENYLHYDRAZINE

5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE Preparation Products And Raw materials

5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE Suppliers

Global( 51)Suppliers
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Shaanxi Dideu Medichem Co. Ltd
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View Lastest Price from 5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE pictures 2025-03-06 5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE
524-81-2
US $0.00 / kg 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
5-BENZYL-2-METHYL-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE MEBHYDROLIN 2,3,4,5-Tetrahydro-2-methyl-5-(phenylmethyl)-1H-pyrido[4,3-b]indole 2,3,4,5-Tetrahydro-2-methyl-5-phenylmethyl-1H-pyrido[4,3-b]indole N-Methyl-9-benzyltetrahydro-γ-carboline 1H-Pyrido[4,3-b]indole, 2,3,4,5-tetrahydro-2-methyl-5-(phenylmethyl)- 3-Benzyl-6-methyl-1,2,3,4-tetrahydro-gamma-carboline 5-Benzyl-1,3,4,5-tetrahydro-2-methyl-2H-pyrido[4,3-b]indole Mebhydroline 5-benzyl-1,2,3,4-tetrahydro-2-methylpyrido(4,3-b)indole 5-benzyl-2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indole Mebhydrolin,inhibit,Histamine Receptor,Inhibitor Mebhydrolin, 10 mM in DMSO Mebhydrin. 524-81-2 Intermediates of Sertraline