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JC-1

JC-1 Structure
JC-1 structure
CAS No.
47729-63-5
Chemical Name:
JC-1
Synonyms
CBIC2;D 383;NK 1420;CBIC2(3);D 383 (DYE);JC-1 IODIDE;6' - tetrachloro - 1;3' - tetraethylbenzimidazolylcarbocyanine iodide;1,1',3,3'-TETRAETHYL-5,5',6,6'-TETRACHLOROIMIDACARBOCYANINE IODIDE;IMIDACARBOCYANINE IODIDE, 1,1',3,3'-TETRAETHYL-5,5',6,6'-TETRACHLORO-
CBNumber:
CB3168099
Molecular Formula:
C25H27Cl4IN4
Molecular Weight:
652.22
MDL Number:
MFCD00188475
MOL File:
47729-63-5.mol
Last updated:2024-03-29 18:52:01
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JC-1 Properties

storage temp. -20C
form solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  22-24/25
WGK Germany  3
F  10-21
HS Code  2933998090

JC-1 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 420200 JC-1 - CAS 47729-63-5 - Calbiochem 47729-63-5 5mg $476 2024-03-01 Buy
Usbiological 452847 JC-1 iodide 47729-63-5 1mg $425 2021-12-16 Buy
AK Scientific 1809AH 5,6-Dichloro-2-(1-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolylidene)propenyl))-1,3-diethylbenzimidazoliumiodide 47729-63-5 10mg $178 2021-12-16 Buy
Apolloscientific BISN0055 JC-1 99% 47729-63-5 5mg $254 2021-12-16 Buy
Product number Packaging Price Buy
420200 5mg $476 Buy
452847 1mg $425 Buy
1809AH 10mg $178 Buy
BISN0055 5mg $254 Buy

JC-1 Chemical Properties,Uses,Production

Uses

JC-1 is commonly used to determine mitochondrial membrane potential. It is a cationic carbocyanine dye that is membrane permeable and is often used for flow cytometry and fluorescent microscopy. This dye changes color as the membrane potential increases. At higher potentials, JC-1 forms aggregates, which changes the fluorescence emission color from green to red. Dyes and metabolites.

Definition

ChEBI: 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide is a cyanine dye and an organic iodide salt. It has a role as a fluorochrome. It contains a 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine.

General Description

A cationic, fluorescent, carbocyanine dye that can be used as a ratiometric indicator of mitochondrial potential ΔΨm in cells, tissues, and isolated mitochondria. It labels mitochondria with high membrane potential orange and mitochondria with low membrane potential green. Mitochondrial depolarization is indicated by a decrease in the red/green fluorescence intensity ratio. Ideal for detection of collapse of ΔΨm induced by uncouplers of mitochondrial respiration. The potential-sensitive color shift is due to concentration-dependent formation of red fluorescent J-aggregates. JC-1 has also been used in a functional assay of multidrug-resistance cells and in apoptosis-related mitochondrial modifications.

Biochem/physiol Actions

Product does not compete with ATP.

storage

-20°C

JC-1 Preparation Products And Raw materials

Raw materials

Preparation Products

JC-1 Suppliers

Global( 67)Suppliers
Supplier Tel Email Country ProdList Advantage
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2995 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Synchem OHG +49 5662 408730 info@synchem.de Germany 4705 70
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51456 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4824 58
Shanghai Han-Xiang Chemical Co., Ltd. 15971444841 amber@biochempartner.com China 3061 58
Suzhou Adelaide Chemical Technology Co., Ltd. 15995785122 3003020078@qq.com China 1198 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684; sales@rrkchem.com China 57412 58
Supplier Advantage
Xian confluore Biological Technology Co., Ltd. 		58
Aladdin Scientific 		58
J & K SCIENTIFIC LTD. 76
Synchem OHG 70
Sigma-Aldrich 80
Shanghai EFE Biological Technology Co., Ltd. 58
Xi'an Confluore Biological Technology Co., Ltd. 58
Shanghai Han-Xiang Chemical Co., Ltd. 58
Suzhou Adelaide Chemical Technology Co., Ltd. 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58

View Lastest Price from JC-1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
JC-1 pictures 2024-03-29 JC-1
47729-63-5
 US $0.00 / mg 25mg >99.00% 25mg Xian confluore Biological Technology Co., Ltd.
  • JC-1 pictures
  • JC-1
    47729-63-5
  • US $0.00 / mg
  • >99.00%
  • Xian confluore Biological Technology Co., Ltd.

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BENZIMIDAZOLOCARBOCYANINE IODIDE, 5,5',6,6'-TETRACHLORO-1,1',3,3'-TETRAETHYL- BIS(5,6-DICHLORO-1,3-DIETHYL-2-BENZIMIDAZOLE)TRIMETHINECYANINE IODIDE IMIDACARBOCYANINE IODIDE, 1,1',3,3'-TETRAETHYL-5,5',6,6'-TETRACHLORO- CBIC2 CBIC2(3) D 383 D 383 (DYE) NK 1420 5,5’,6,6’-tetrachloro-1,1’,3,3’-tetraethylbenzimidazolylcarbocyanineiodide(jc-1 (E)-5,6-Dichloro-2-(3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzo[d]imidazol-2-ylidene)prop CBIC2(3) 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolylcarbocyanine iodide JC-1 IODIDE 1,1',3,3'-TETRAETHYL-5,5',6,6'-TETRACHLOROBENZIMIDAZOLOCARBOCYANINE IODIDE 1,1',3,3'-TETRAETHYL-5,5',6,6'-TETRACHLOROIMIDACARBOCYANINE IODIDE 1H-BENZIMIDAZOLIUM, 5,6-DICHLORO-2-[3-(5,6-DICHLORO-1,3-DIETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-YLIDENE)-1-PROPENYL]-1,3-DIETHYL-, IODIDE 1-DODECYL-2-[(E)-3-(1-DODECYL-3,3-DIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)-1-PROPENYL]-3,3-DIMETHYL-3H-INDOLIUM PERCHLORATE 3H-INDOLIUM, 1-DODECYL-2-[3-(1-DODECYL-1,3-DIHYDRO-3,3-DIMETHYL-2H-INDOL-2-YLIDENE)-1-PROPENYL]-3,3-DIMETHYL-, PERCHLORATE 5,5',6,6'-TETRACHLORO-1,1',3,3'-TETRAETHYLBENZIMIDAZOLYLCARBOCYANINE IODIDE 5,6-DICHLORO-2-[3-(5,6-DICHLORO-1,3-DIETHYL-2-BENZIMIDAZOLINYLIDENE)PROPENYL]-1,3-DIETHYLBENZIMIDAZOLIUM IODIDE 5,6-DICHLORO-2-[(E)-3-(5,6-DICHLORO-1,3-DIETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-YLIDENE)-1-PROPENYL]-1,3-DIETHYL-3H-BENZIMIDAZOL-1-IUM IODIDE BENZIMIDAZOLIUM, 5,6-DICHLORO-2-[3-(5,6-DICHLORO-1,3-DIETHYL-2-BENZIMIDAZOLINYLIDENE)PROPENYL]-1,3-DIETHYL-, IODIDE 3' - tetraethylbenzimidazolylcarbocyanine iodide 6' - tetrachloro - 1 (E)-5,6-Dichloro-2-(3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzo[d]imidazol-2-ylidene)prop-1-en-1-yl)-1,3-diethyl-1H-benzo[d]imidazol-3-ium iodide 47729-63-5 C25H27Cl4IN4 C25H27Cl4N4I C25H27N4Cl4I Lipophilic and Membrane Probes Alphabetical Fluorescent Indicators and Probes Fluorescent Probes, Labels, Particles and Stains BioChemical Biochemicals and Reagents