ChemicalBook >> CAS DataBase List >>(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]-
N-cyclohexylpiperidine-3-carboxamide
(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide
- CAS No.
- 872506-67-7
- Chemical Name:
- (3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide
- Synonyms
- 11β-HSD1-IN-12;(S)-1-((3-Chloro-2-methylphenyl)sulfonyl)-N-cyclohexylpiperidine-3-carboxamide;(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide;3-Piperidinecarboxamide, 1-[(3-chloro-2-methylphenyl)sulfonyl]-N-cyclohexyl-, (3S)-
- CBNumber:
- CB31874274
- Molecular Formula:
- C19H27ClN2O3S
- Molecular Weight:
- 398.95
- MDL Number:
- MFCD11226407
- MOL File:
- 872506-67-7.mol
- MSDS File:
- SDS
Last updated:2023-03-31 09:12:57
(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide price More Price(2)
(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide Chemical Properties,Uses,Production
Description
INCB13739 is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) for the treatment of type 2 diabetes. INCB-13739 has high selectivity for 11beta-HSD1 over other dehydrogenases and glucocorticoid and mineralocorticoid receptors, with prolonged pharmacodynamic activity and good pharmacokinetic/pharmacodynamic properties. INCB-13739 demonstrated improved hepatic and peripheral insulin sensitivity with a satisfactory reduction in fasting plasma glucose and cholesterol
(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide Suppliers
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(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]-
N-cyclohexylpiperidine-3-carboxamide
11β-HSD1-IN-12
3-Piperidinecarboxamide, 1-[(3-chloro-2-methylphenyl)sulfonyl]-N-cyclohexyl-, (3S)-
(S)-1-((3-Chloro-2-methylphenyl)sulfonyl)-N-cyclohexylpiperidine-3-carboxamide
872506-67-7