(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide
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- $503.65 - $1067.85
- Product name: (3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide
- CAS: 872506-67-7
- MF: C19H27ClN2O3S
- MW: 398.95
- EINECS:
- MDL Number:MFCD11226407
- Synonyms:(3S)-1-[(3-chloro-2-methylbenzene)sulfonyl]- N-cyclohexylpiperidine-3-carboxamide;11β-HSD1-IN-12;3-Piperidinecarboxamide, 1-[(3-chloro-2-methylphenyl)sulfonyl]-N-cyclohexyl-, (3S)-;(S)-1-((3-Chloro-2-methylphenyl)sulfonyl)-N-cyclohexylpiperidine-3-carboxamide
2 prices
Selected condition:
Brand
- American Custom Chemicals Corporation
Package
- 5MG
- 1G
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000438
- Product descriptionINCB-13739 95.00%
- Packaging5MG
- Price$503.65
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000438
- Product descriptionINCB-13739 95.00%
- Packaging1G
- Price$1067.85
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
American Custom Chemicals Corporation | KIN0000438 | INCB-13739 95.00% | 5MG | $503.65 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000438 | INCB-13739 95.00% | 1G | $1067.85 | 2021-12-16 | Buy |
Properties
Density :1.29±0.1 g/cm3(Predicted)
pka :15.29±0.20(Predicted)
pka :15.29±0.20(Predicted)
Safety Information
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Description
INCB13739 is a potent, selective, oral 11βHSD1 inhibitor (IC50=1.1 nM) for the treatment of type 2 diabetes. INCB-13739 has high selectivity for 11beta-HSD1 over other dehydrogenases and glucocorticoid and mineralocorticoid receptors, with prolonged pharmacodynamic activity and good pharmacokinetic/pharmacodynamic properties. INCB-13739 demonstrated improved hepatic and peripheral insulin sensitivity with a satisfactory reduction in fasting plasma glucose and cholesterolSuppliers and manufacturers
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