PALMITOYL COENZYME A POTASSIUM SALT
- CAS No.
- 1763-10-6
- Chemical Name:
- PALMITOYL COENZYME A POTASSIUM SALT
- Synonyms
- Palmityl-CoA;PALMITOYL-COA;Palmityl coenzyme A;Palmitoyl Coenzyme A;S-palmitoylcoenzyme A;Coenzyme A S-palmitate;Coenzyme A S-hexadecanoate;PALMITOYL COENZYME A, K SALT;coenzyme A palmitoyl derivative;PALMITOYL COENZYME A POTASSIUM SALT
- CBNumber:
- CB3200160
- Molecular Formula:
- C37H66N7O17P3S
- Molecular Weight:
- 1005.94
- MDL Number:
- MFCD02259056
- MOL File:
- 1763-10-6.mol
- MSDS File:
- SDS
PALMITOYL COENZYME A POTASSIUM SALT price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Usbiological | 296397 | Palmitoyl Coenzyme A Potassium Salt | 1763-10-6 | 1mg | $333 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | ENZ0000731 | S-PALMITOYL COENZYME A POTASSIUM SALT 95.00% | 1763-10-6 | 5MG | $499.98 | 2021-12-16 | Buy |
Biosynth Carbosynth | NP46059 | Palmitoyl coenzyme A potassium salt | 1763-10-6 | 25mg | $525 | 2021-12-16 | Buy |
Biosynth Carbosynth | NP46059 | Palmitoyl coenzyme A potassium salt | 1763-10-6 | 1mg | $65 | 2021-12-16 | Buy |
Biosynth Carbosynth | NP46059 | Palmitoyl coenzyme A potassium salt | 1763-10-6 | 2mg | $110 | 2021-12-16 | Buy |
PALMITOYL COENZYME A POTASSIUM SALT Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
Palmitoyl coenzyme A is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A can also be used as a substrate for sphingosine biosynthesis[1][2].
Definition
ChEBI: Palmitoyl-CoA is a long-chain fatty acyl-CoA resulting from the formal condensation of the carboxy group of hexadecanoic acid with the thiol group of coenzyme A. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a long-chain fatty acyl-CoA, a palmitoyl bioconjugate, an 11,12-saturated fatty acyl-CoA and a 3-substituted propionyl-CoA. It is functionally related to a coenzyme A, a hexadecanoic acid and a hexadecanoate. It is a conjugate acid of a palmitoyl-CoA(4-).
Purification Methods
Possible impurities are palmitic acid, S-palmitoyl thioglycolic acid and S-palmitoyl glutathione. These are removed by placing ca 200mg in a centrifuge tube and extracting with Me2CO (20mL), followed by two successive extractions with Et2O (15mL) to remove S-palmitoyl thioglycolic acid and palmitic acid. The residue is dissolved in H2O (4 x 4 mL), adjusted to pH 5 and centrifuged to remove insoluble S-palmitoyl glutathione and other insoluble impurities. To the clear supernatant is added 5% HClO4 (6mL) whereby S-palmitoyl CoA precipitates. The precipitate is washed with 0.8% HClO4 (10mL) and finally with Me2CO (3x 5mL) and dried in vacuo. It is stable for at least one year in dry form at 0o in a desiccator (dark). Solutions are stable for several months at -15o. Its solubility in H2O is 4%. The adenine content is used as the basis of purity with max at 260 and 232nm ( 6.4 x 106 and 9.4 x 106 cm2/mol, respectively). Higher absorption at 232nm would indicate other thio ester impurities, e.g. S-palmitoyl glutathione, which absorb highly at this wavelength. Also the phosphate content should be determined, and acid phosphate can be titrated potentiometrically. [Seubert Biochemical Preparations 7 80 1960, Srer et al. Biochim Biophys Acta 33 31 1959, Kornberg & Pricer J Biol Chem 204 329 , 345 1953, Beilstein 26 III/IV 3665.]
References
[1] A G Goodridge, et al. Regulation of the activity of acetyl coenzyme A carboxylase by palmitoyl coenzyme A and citrate. J Biol Chem. 1972 Nov 10;247(21):6946-52. PMID:5082134
[2] L A Fahien, et al. Regulation of glutamate dehydrogenase by palmitoyl-coenzyme A. Arch Biochem Biophys. 1981 Nov;212(1):247-53. DOI:10.1016/0003-9861(81)90364-7
PALMITOYL COENZYME A POTASSIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
PALMITOYL COENZYME A POTASSIUM SALT Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
Chizhou Kailong Import and Export Trade Co., Ltd. | xg01_gj@163.com | China | 9484 | 50 | |
BOC Sciences | 16314854226 | inquiry@bocsci.com | United States | 9713 | 58 |
Hubei Guangao Biotechnology Co., Ltd | 027-027-59223056 18162699093 | 1208480011@qq.com | China | 9888 | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 13675144456 | alan.chow@synzest.com | China | 9470 | 58 |
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 029-81120477 17792793610 | 1033@dideu.com | China | 9763 | 58 |
Shanghai Kaisen Biotechnology Co., Ltd | 17558870519 | 3549952815@qq.com | China | 2979 | 58 |