ChemicalBook >> CAS DataBase List >>4-Hydroxybenzyl alcohol

4-Hydroxybenzyl alcohol

CAS No.
623-05-2
Chemical Name:
4-Hydroxybenzyl alcohol
Synonyms
4-(Hydroxymethyl)phenol;P-HYDROXYBENZYL ALCOHOL;Gastrodigenin;p-Hydroxybenzyl;p-Methylolphenol;4-hydroxyphenyl Methanol;P-hydroxylbenzyl alcohol;Benzenemethanol, 4-hydroxy-;FEMA 3987;ω-Hydroxycresol
CBNumber:
CB3224331
Molecular Formula:
C7H8O2
Molecular Weight:
124.14
MDL Number:
MFCD00004658
MOL File:
623-05-2.mol
MSDS File:
SDS
Last updated:2024-11-17 16:00:36

4-Hydroxybenzyl alcohol Properties

Melting point 114-122 °C(lit.)
Boiling point 251-253°C
Density 1.1006 (rough estimate)
refractive index 1.5035 (estimate)
FEMA 3987 | 4-HYDROXYBENZYL ALCOHOL
Flash point 251-253°C
storage temp. Store below +30°C.
solubility 6.7g/l soluble
form Crystalline Powder
pka pK1:9.82 (25°C)
color Pink to beige
Odor at 100.00 %. fruity bitter almond sweet coconut
Odor Type fruity
Water Solubility Soluble in water (6.7 mg/ml at 20°C), dioxane (100 mg/ml), 1N NaOH (50 mg/ml), DMSO, and methanol.
Sensitive Light Sensitive/Air Sensitive
JECFA Number 955
BRN 1858967
InChIKey BVJSUAQZOZWCKN-UHFFFAOYSA-N
LogP 0.21
CAS DataBase Reference 623-05-2(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) 4-HYDROXYBENZYL ALCOHOL
EWG's Food Scores 5
FDA UNII 1A3AH1FP1B
NIST Chemistry Reference Benzenemethanol, 4-hydroxy-(623-05-2)
EPA Substance Registry System 4-Hydroxybenzenemethanol (623-05-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H412
Precautionary statements  P264-P273-P280-P305+P351+P338-P337+P313-P501
Hazard Codes  Xi
Risk Statements  36-36/37/38
Safety Statements  26-24/25-36
WGK Germany  3
RTECS  DA4796800
8-9-23
Hazard Note  Irritant/Keep Cold/Air Sensitive/Light Sensitive
HS Code  29072900
NFPA 704
1
2 0

4-Hydroxybenzyl alcohol price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H20806 4-Hydroxybenzyl alcohol 99% 623-05-2 10g $58.9 2024-03-01 Buy
TCI Chemical H0224 4-Hydroxybenzyl Alcohol >97.0%(GC) 623-05-2 25g $30 2024-03-01 Buy
TCI Chemical H0224 4-Hydroxybenzyl Alcohol >97.0%(GC) 623-05-2 100g $115 2024-03-01 Buy
Alfa Aesar A13132 4-Hydroxybenzyl alcohol, 99% 623-05-2 50g $82.3 2024-03-01 Buy
Alfa Aesar A13132 4-Hydroxybenzyl alcohol, 99% 623-05-2 100g $145.65 2024-03-01 Buy
Product number Packaging Price Buy
H20806 10g $58.9 Buy
H0224 25g $30 Buy
H0224 100g $115 Buy
A13132 50g $82.3 Buy
A13132 100g $145.65 Buy

4-Hydroxybenzyl alcohol Chemical Properties,Uses,Production

Chemical Properties

Pink to beige crystalline powder

Chemical Properties

4-Hydroxybenzyl alcohol is a white crystalline powder with slightly fruity-sweet coconut odor

Occurrence

Reportedly found in vanilla, Bourbon (Vanilla plantifolia Andrew

Uses

4-Hydroxybenzyl alcohol is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Definition

ChEBI: P-hydroxybenzyl alcohol is a member of the class of benzyl alcohols that is benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from Arcangelisia gusanlung. It has a role as a plant metabolite. It is a member of phenols and a member of benzyl alcohols.

Preparation

Prepared from p-cresol by using the microorganism, Pseudomonas putida.

General Description

4-Hydroxybenzyl alcohol (HBA) is a phenolic compound found in Gastrodia elata. It is as an antioxidant and anti-asthmatic agent.

Flammability and Explosibility

Not classified

Contact allergens

Methylol phenols are sensitizers contained in resins based on phenol and formaldehyde of the resol type. Cross-reactivity is possible with other phenol derivative molecules.

IC 50

IC50 >0.2 mM (human); ALDH5A1: IC50 >1 mM (human); ABAT: IC50 >1 mM (human); Tyrosinase: IC50 >1 mM (Agaricus bisporus)

Purification Methods

Crystallise the alcohol from H2O, *C6H6 (m 124o), *C6H6/EtOH or ClCH2CH2Cl (m 122o). [Beilstein 6 III 4546, 6 IV 5909.]

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View Lastest Price from 4-Hydroxybenzyl alcohol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Hydroxybenzyl Alcohol pictures 2024-11-22 4-Hydroxybenzyl Alcohol
623-05-2
US $100.00-45.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
4-Hydroxybenzyl alcohol pictures 2024-11-21 4-Hydroxybenzyl alcohol
623-05-2
US $0.00-0.00 / Kg/Drum 5KG 99%min 15tons/month WUHAN FORTUNA CHEMICAL CO., LTD
4-Hydroxybenzyl alcohol pictures 2024-11-18 4-Hydroxybenzyl alcohol
623-05-2
US $50.00-500.00 / KG 1KG 98% 20MT per month Anhui Dexinjia Biopharm Co., Ltd
4-(Hydroxymethyl)phenol 98% 4-Hydroxybenzyl alcohol, (4-Hydroxyphenyl)methanol 4-Hydroxybenzyl alcohol, 97% 25GR The hydroxy benzyl alcohol P-(HYDROXYMETHYL)PHENOL RARECHEM AL BD 0098 4-METHYLOLPHENOL 4-HYDROXYBENZYL ALCOHOL 4-hydroxybenzenemethanol HYDROXYBENZYL-4 ALCOHOL FEMA 3987 alpha-Hydroxy-p-cresol Benzyl alcohol, p-hydroxy- p-Hydroxy Benzyl Alcohol 4-Hydroxy Benzyl Alcohol 4-HYDROXYBENZYL ALCOHOL 98+% 4-HydroxybenzylAlcohol99% PARA-HYDROXYBENZOYLALCOHOL PARA-ALCOHOLPHENOL 4-HYDROXYBENZYL ALCOHOL 99% p-Hydroxybenzenemethanol ω-Hydroxycresol 4-Hydroxybenzyl alcohol,97% 4-Hydroxbenzyl alcohol (4-hydroxybenzyl)ether 4-Hydroxybenzylic Alcohol Bisoprolol Impurity 19 α,4‐Dihydroxytoluene 4 Hydroxy benzyl alcohol (CAS No: 623-05-2) Bisoprolol Alcohol Impurity (Gastrodigenin) 4-Hydroxybenzyl Alcohol > 4-HYDROXYBENZYL ALCOHOL FOR SYNTHESIS Bisoprolol Impurity 13 (Gastrodigenin) Para Hydroxylbenzyl alcohol Bisoprolol Impurity 33 4-(Hydroxymethyl)phenol (BPL-I) 4-Hydroxy Benzyl Alcohol pure, 98% Bisoprolol Alcohol ImpurityQ: What is Bisoprolol Alcohol Impurity Q: What is the CAS Number of Bisoprolol Alcohol Impurity Q: What is the storage condition of Bisoprolol Alcohol Impurity Q: What are the applications of Bisoprolol Alcohol Impurity 4-hydroxyphenyl Methanol P-HYDROXYBENZYL ALCOHOL P-hydroxylbenzyl alcohol 4-(Hydroxymethyl)phenol Gastrodigenin p-Methylolphenol p-Hydroxybenzyl Benzenemethanol, 4-hydroxy- 4-HYDROXY BENZYLALCHOHOL PARA HYDROXY BENZYL ALCOHOL 4-Hydroxybenzyl alcohol, p-Hydroxybenzyl alcohol, 4-(Hydroxymethyl)phenol, Gastrodigenin, p-Hydroxybenzyl, p-Methylolphenol, 4-hydroxyphenyl Methanol, p-hydroxylbenzyl alcohol, Benzenemethanol, 4-hydroxy-, FEMA 3987, ω-Hydroxycresol 623-05-2 0623-05-02 Alcohols Building Blocks C7 to C8 Organic Building Blocks Oxygen Compounds Aromatics Benzhydrols, Benzyl & Special Alcohols Alphabetical Listings