4-Hydroxybenzyl alcohol
- CAS No.
- 623-05-2
- Chemical Name:
- 4-Hydroxybenzyl alcohol
- Synonyms
- 4-(Hydroxymethyl)phenol;P-HYDROXYBENZYL ALCOHOL;Gastrodigenin;p-Hydroxybenzyl;p-Methylolphenol;4-hydroxyphenyl Methanol;P-hydroxylbenzyl alcohol;Benzenemethanol, 4-hydroxy-;FEMA 3987;ω-Hydroxycresol
- CBNumber:
- CB3224331
- Molecular Formula:
- C7H8O2
- Molecular Weight:
- 124.14
- MDL Number:
- MFCD00004658
- MOL File:
- 623-05-2.mol
- MSDS File:
- SDS
Melting point | 114-122 °C(lit.) |
---|---|
Boiling point | 251-253°C |
Density | 1.1006 (rough estimate) |
refractive index | 1.5035 (estimate) |
FEMA | 3987 | 4-HYDROXYBENZYL ALCOHOL |
Flash point | 251-253°C |
storage temp. | Store below +30°C. |
solubility | 6.7g/l soluble |
form | Crystalline Powder |
pka | pK1:9.82 (25°C) |
color | Pink to beige |
Odor | at 100.00 %. fruity bitter almond sweet coconut |
Odor Type | fruity |
Water Solubility | Soluble in water (6.7 mg/ml at 20°C), dioxane (100 mg/ml), 1N NaOH (50 mg/ml), DMSO, and methanol. |
Sensitive | Light Sensitive/Air Sensitive |
JECFA Number | 955 |
BRN | 1858967 |
InChIKey | BVJSUAQZOZWCKN-UHFFFAOYSA-N |
LogP | 0.21 |
CAS DataBase Reference | 623-05-2(CAS DataBase Reference) |
Substances Added to Food (formerly EAFUS) | 4-HYDROXYBENZYL ALCOHOL |
EWG's Food Scores | 5 |
FDA UNII | 1A3AH1FP1B |
NIST Chemistry Reference | Benzenemethanol, 4-hydroxy-(623-05-2) |
EPA Substance Registry System | 4-Hydroxybenzenemethanol (623-05-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H319-H412 | |||||||||
Precautionary statements | P264-P273-P280-P305+P351+P338-P337+P313-P501 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36-36/37/38 | |||||||||
Safety Statements | 26-24/25-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | DA4796800 | |||||||||
F | 8-9-23 | |||||||||
Hazard Note | Irritant/Keep Cold/Air Sensitive/Light Sensitive | |||||||||
HS Code | 29072900 | |||||||||
NFPA 704 |
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4-Hydroxybenzyl alcohol price More Price(46)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | H20806 | 4-Hydroxybenzyl alcohol 99% | 623-05-2 | 10g | $58.9 | 2024-03-01 | Buy |
TCI Chemical | H0224 | 4-Hydroxybenzyl Alcohol >97.0%(GC) | 623-05-2 | 25g | $30 | 2024-03-01 | Buy |
TCI Chemical | H0224 | 4-Hydroxybenzyl Alcohol >97.0%(GC) | 623-05-2 | 100g | $115 | 2024-03-01 | Buy |
Alfa Aesar | A13132 | 4-Hydroxybenzyl alcohol, 99% | 623-05-2 | 50g | $82.3 | 2024-03-01 | Buy |
Alfa Aesar | A13132 | 4-Hydroxybenzyl alcohol, 99% | 623-05-2 | 100g | $145.65 | 2024-03-01 | Buy |
4-Hydroxybenzyl alcohol Chemical Properties,Uses,Production
Chemical Properties
Pink to beige crystalline powder
Chemical Properties
4-Hydroxybenzyl alcohol is a white crystalline powder with slightly fruity-sweet coconut odor
Occurrence
Reportedly found in vanilla, Bourbon (Vanilla plantifolia Andrew
Uses
4-Hydroxybenzyl alcohol is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
Definition
ChEBI: P-hydroxybenzyl alcohol is a member of the class of benzyl alcohols that is benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from Arcangelisia gusanlung. It has a role as a plant metabolite. It is a member of phenols and a member of benzyl alcohols.
Preparation
Prepared from p-cresol by using the microorganism, Pseudomonas putida.
General Description
4-Hydroxybenzyl alcohol (HBA) is a phenolic compound found in Gastrodia elata. It is as an antioxidant and anti-asthmatic agent.
Flammability and Explosibility
Not classified
Contact allergens
Methylol phenols are sensitizers contained in resins based on phenol and formaldehyde of the resol type. Cross-reactivity is possible with other phenol derivative molecules.
IC 50
IC50 >0.2 mM (human); ALDH5A1: IC50 >1 mM (human); ABAT: IC50 >1 mM (human); Tyrosinase: IC50 >1 mM (Agaricus bisporus)
Purification Methods
Crystallise the alcohol from H2O, *C6H6 (m 124o), *C6H6/EtOH or ClCH2CH2Cl (m 122o). [Beilstein 6 III 4546, 6 IV 5909.]
4-Hydroxybenzyl alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
PNP Biotech Co. Ltd | +8618516098983 | sales@pnpbiotech.com | China | 1001 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20287 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
JINING XINHE CHEMICAL CO., LTD | +8615318402391 | sales@xinhepharma.com | China | 809 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18779 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
View Lastest Price from 4-Hydroxybenzyl alcohol manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-22 | 4-Hydroxybenzyl Alcohol
623-05-2
|
US $100.00-45.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | ||
2024-11-21 | 4-Hydroxybenzyl alcohol
623-05-2
|
US $0.00-0.00 / Kg/Drum | 5KG | 99%min | 15tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-11-18 | 4-Hydroxybenzyl alcohol
623-05-2
|
US $50.00-500.00 / KG | 1KG | 98% | 20MT per month | Anhui Dexinjia Biopharm Co., Ltd |
- 4-Hydroxybenzyl Alcohol
623-05-2
- US $100.00-45.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
- 4-Hydroxybenzyl alcohol
623-05-2
- US $0.00-0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- 4-Hydroxybenzyl alcohol
623-05-2
- US $50.00-500.00 / KG
- 98%
- Anhui Dexinjia Biopharm Co., Ltd