ChemicalBook >> CAS DataBase List >>N-Boc-L-tert-Leucine

N-Boc-L-tert-Leucine

N-Boc-L-tert-Leucine structure

CAS No.: 62965-35-9

Chemical Name:: N-Boc-L-tert-Leucine

Synonyms: BOC-L-TERT-LEUCINE;BOC-TLE-OH;N-(TERT-BUTOXYCARBONYL)-L-TERT-LEUCINE;BOC-TLE;BOC-L-ALPHA-T-BUTYLGLYCINE;N-Boc-L-tert-leucine,99%e.e.;N-(METHOXYCARBONYL)-L-TERT-LEUCINE;BOC-L-TLE-OH;Boc-Tle-OH-d9;BOC-TBU-GLY-OH

CBNumber:: CB3225606

Molecular Formula:: C11H21NO4

Molecular Weight:: 231.29

MDL Number:: MFCD00065574

MOL File:: 62965-35-9.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

Request For Quotation

N-Boc-L-tert-Leucine Properties

Melting point	118-121 °C
alpha	-4.2 º (c=1% in glacial acetic acid)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	Crystalline Powder
color	White to slightly yellow
optical activity	[α]20/D 4.2±0.5°, c = 1% in glacial acetic acid
BRN	1962763
InChI	InChI=1/C11H21NO4/c1-10(2,3)7(8(13)14)12-9(15)16-11(4,5)6/h7H,1-6H3,(H,12,15)(H,13,14)/t7-/s3
InChIKey	LRFZIPCTFBPFLX-SSDOTTSWSA-N
SMILES	[C@@H](C(=O)O)(C(C)(C)C)NC(=O)OC(C)(C)C \|&1:0,r\|
CAS DataBase Reference	62965-35-9(CAS DataBase Reference)
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314-H290

Precautionary statements

P501-P260-P234-P264-P280-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P406-P405

Safety Statements

24/25

WGK Germany

HS Code

2924 19 00

HazardClass

IRRITANT

NFPA 704

	1
0		0

N-Boc-L-tert-Leucine price More Price(57)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	15451	Boc-Tle-OH ≥99.0% (T)	62965-35-9	5G	$83.2	2024-03-01	Buy
Sigma-Aldrich	8.53068	Boc-L-α-t-butylglycine Novabiochem?	62965-35-9	5G	$153	2024-03-01	Buy
Sigma-Aldrich	15451	Boc-Tle-OH ≥99.0% (T)	62965-35-9	25g	$303	2024-03-01	Buy
TCI Chemical	B3754	N-(tert-Butoxycarbonyl)-L-tert-leucine >98.0%(HPLC)(T)	62965-35-9	5g	$68	2024-03-01	Buy
TCI Chemical	B3754	N-(tert-Butoxycarbonyl)-L-tert-leucine >98.0%(HPLC)(T)	62965-35-9	25g	$239	2024-03-01	Buy

Product number	Packaging	Price	Buy
15451	5G	$83.2	Buy
8.53068	5G	$153	Buy
15451	25g	$303	Buy
B3754	5g	$68	Buy
B3754	25g	$239	Buy

N-Boc-L-tert-Leucine Chemical Properties,Uses,Production

Description

N-Boc-L-tert-Leucine is a white to slightly yellow crystalline powder. The carboxyl group in its structure can be condensed with alcohol compounds under the catalysis of acid or base to obtain the corresponding ester derivatives. This substance can be used for the synthesis of amino acid drugs due to the various chemical transformation properties of its amine and carboxyl groups. The Boc protective group is able to protect the amino group of the amino acid from non-specific reactions with other reactants. This compound is a derivative of L-tert-Leucine, which is a non-polar amino acid. Its tert-butyl group exhibits significant hydrophobicity and steric hindrance, enabling effective control of molecular conformation in chemical reactions, leading to the formation of chiral compounds. As a crucial chiral intermediate, L-tert-leucine is widely employed in the synthesis of anti-cancer, anti-viral, and biological inhibitors. Additionally, L-tert-leucine serves as an essential additive in the food and cosmetic industry.

Chemical Properties

White crystalline powder

Uses

Atazanavir Related Compound A

reaction suitability

reaction type: Boc solid-phase peptide synthesis
reaction type: C-H Activation
reagent type: ligand
reaction type: Peptide Synthesis

N-Boc-L-tert-Leucine synthesis

Synthesis of N-Boc-L-tert-Leucine from L-tert-Leucine and Di-tert-butyl dicarbonate

N-Boc-L-tert-Leucine Preparation Products And Raw materials

Raw materials

Preparation Products

methyl (2S)-2-amino-3,3-dimethylbutanoate Methoxycarbonyl-L-tert-leucine Asunaprevir (S)-tert-butyl (3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)carbamate(WXC08256) L-tert-Leucine methyl ester hydrochloride

(S)-benzyl 2-amino-3,3-dimethylbutanoate(WXG02404) L-tert-Leucine

1of2

N-Boc-L-tert-Leucine Suppliers

Global( 489)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8615965530500	nickzhang@hangyubiotech.com	China	10983	58
Firsky International Trade (Wuhan) Co., Ltd	+8615387054039	admin@firsky-cn.com	China	427	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29730	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-+86-371-66670886	info@dakenam.com	China	19843	58
Taizhou Tianhong Biochemistry Technology Co., Ltd.	0523-86132544	sales@thbiochem.com	CHINA	305	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21628	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29858	58
Anhui Dexinjia Biopharm Co., Ltd	+86-531-82371986 +86-15064117275	sales01@jndxj.com	China	290	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58

Supplier	Advantage
Zibo Hangyu Biotechnology Development Co., Ltd	58
Firsky International Trade (Wuhan) Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Taizhou Tianhong Biochemistry Technology Co., Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Anhui Dexinjia Biopharm Co., Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58

View Lastest Price from N-Boc-L-tert-Leucine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-28	N-Boc-L-tert-Leucine 62965-35-9	US $0.00 / Kg/Drum	1KG	98%min	1000kg	WUHAN FORTUNA CHEMICAL CO., LTD
2025-04-22	N-Boc-L-tert-Leucine 62965-35-9	US $65.00-650.00 / KG	1KG	0.99	20 tons	Zibo Hangyu Biotechnology Development Co., Ltd
2025-04-04	N-Boc-L-tert-Leucine 62965-35-9	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

N-Boc-L-tert-Leucine
62965-35-9
US $0.00 / Kg/Drum
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

N-Boc-L-tert-Leucine
62965-35-9
US $65.00-650.00 / KG
0.99
Zibo Hangyu Biotechnology Development Co., Ltd

N-Boc-L-tert-Leucine
62965-35-9
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

62965-35-9(N-Boc-L-tert-Leucine)Related Search:

3-Aminophenol tert-Butanol ALTRENOGEST N-Carbobenzyloxyglycine L-tert-Leucine

6-Aminocaproic acid Glycine N-CARBOBENZOXY-DL-LEUCINE Tris(hydroxymethyl)aminomethane N-Boc-L-Phenylalaninol

BOC-L-Prolinol N-Boc-L-alaninol BOC-L-NORLEUCINE Methoxycarbonyl-L-tert-leucine BOC-D-TERT-LEUCINE,N-BOC-D-TERT-LEUCINE

(2S,4R)-N-Boc-4-hydroxy-3,3-dimethylpyrrolidine-2-carboxylic acid (S)-N-Boc-3,3-dimethylpyrrolidine-2-carboxylic acid (S)-Boc-1-adamantyl-glycine

1of4

BOC-TBU-GLYCINE BOC-TBU-GLY-OH BOC-ALPHA-BUTYLGLYCINE BOC-ALPHA-T-BUTYLGLYCINE BOC-ALPHA-T-BUTYLGLYCINE-OH BOC-ALPHA-T-BUTYL-GLY-OH BOC-L-TLE-OH BOC-L-T-BUTYLGLYCINE RARECHEM EM WB 0082 (S)-N-(TERT-BUTOXYCARBONYL)-TERT-LEUCINE (S)-N-BOC-2-AMINO-3,3-DIMETHYLBUTYRIC ACID N-ALPHA-TERT-BUTYLOXYCARBONYL-L-TERT-BUTYLGLYCINE N-ALPHA-TERT-BUTYLOXYCARBONYL-L-T-LEUCINE N-ALPHA-T-BUTOXYCARBONYL-L-ALPHA-T-BUTYL-GLYCINE N-ALPHA-T-BUTOXYCARBONYL-L-T-BUTYLGLYCINE N-ALPHA-T-BUTOXYCARBONYL-L-T-LEUCINE N-ALPHA-T-BUTYLOXYCARBONYL-L-T-LEUCINE N-ALPHA-T-BUTOXYCARBONYL-(S)-2-AMINO-3,3-DIMETHYL-BUTYRIC ACID N-ALPHA-T-BOC-L-T-LEUCINE N-ALPHA-T-BOC-L-ALPHA-T-BUTYL-GLYCINE N-BOC-(L)-T-LEUCINE N-BOC-L-TERT-LEUCINE L-Valine, N-(1,1-dimethylethoxy)carbonyl-3-methyl- BOC-L-T-LEUCINE Boc-L-α-tert-butylglycine≥ 98% (HPLC) Boc-L-α-tert-butyl-Gly-OH Boc-L-α-t-butylglycine Novabiochem BOC-L-2-AMINO-3,3-DIMETHYLBUTANOIC ACID N-alpha-t-Butyloxycarbonyl-L-t-leucine, N-alpha-t-Butyloxycarbonyl-L-t-butylglycine Boc--t-Butylglycine (S)-2-(tert-butoxycarbonyl)-3,3-dimethylbutanoic a BOC-L-TERT-BUTYLGLYCINE (S)-N-Boc-2-amino-3,3-dimethylbutyric acid, Boc-L-tert-leucine Boc-a-tert-Butyl-Gly-OH N-BOC-L-tert-Leucine,98% N-BOC-L-tert-LeucineN-(tert-Butoxycarbonyl)-L-leucine Boc-Tle-OH (Boc-tertleucine) N-BOC-L-tert-Leucine, 98% 5GR (2S)-2-(tert-ButoxycarbonylaMino)-3,3-diMethylbutanoic Acid (S)-2-(((tert-Butoxy)carbonyl)aMino)-3,3-diMethylbutanoic Acid (S)-2-tert-ButoxycarbonylaMino-3,3-diMethylbutyric Acid N-tert-Butoxyc (S)-2-(tert-Butoxycarbonylamino)-3,3-dimethylbutyric Acid (S)-2-(Boc-amino)-3,3-dimethylbutyric Acid N-Boc-L-tert-leucine Boc-Tle-OH BOC-L-tert-Leucine,Boc-Alpha-ButylGlycine (Tert-Butoxy)Carbonyl Tle-OH Boc-Tle-OH-d9 N-(tert-Butoxycarbonyl)-L-tert-leucine > Boc-Tle-OH Boc-?-tert-butyl-Gly-OH (S)-2-(Boc-amino)-3,3-dimethylbutyric Acid N-Boc-L-tert-Leucine USP/EP/BP Boc-L-α-tert-butylglycine Tert butoxycarbonyl-l-tert leucine (2S)-3,3-dimethyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid BOC-Tert-leu-OH Nirmatrelvir Impurity 21 Boc-Tle-OH, ≥99% TIANFU-CHEM 62965-35-9 N-Boc-L-tert-Leucine Paxlovid Impurity 4