2-Cyanobenzyl bromide

2-Cyanobenzyl bromide Properties

Melting point	72-74 °C(lit.)
Boiling point	111 °C / 1.5mmHg
Density	1.5466 (rough estimate)
refractive index	1.6550 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Water Solubility	Slightly soluble in water
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
form	Crystalline Powder or Chunks
color	White to gray-brown
BRN	742605
InChIKey	QGXNHCXKWFNKCG-UHFFFAOYSA-N
CAS DataBase Reference	22115-41-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363

Hazard Codes

C

Risk Statements

34

Safety Statements

26-36/37/39-45-28A

RIDADR

UN 3261 8/PG 2

WGK Germany

3

F

10-19-21

Hazard Note

Corrosive

HazardClass

8

PackingGroup

II

HS Code

29269090

NFPA 704

	0
3		0

2-Cyanobenzyl bromide price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	144711	2-(Bromomethyl)benzonitrile ≥97%	22115-41-9	5g	$49.1	2024-03-01	Buy
Sigma-Aldrich	144711	2-(Bromomethyl)benzonitrile ≥97%	22115-41-9	25g	$64	2024-03-01	Buy
TCI Chemical	C1556	2-Cyanobenzyl Bromide >98.0%(GC)	22115-41-9	10g	$68	2024-03-01	Buy
TCI Chemical	C1556	2-Cyanobenzyl Bromide >98.0%(GC)	22115-41-9	25g	$132	2024-03-01	Buy
Alfa Aesar	B24278	2-(Bromomethyl)benzonitrile, 98%	22115-41-9	25g	$135.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
144711	5g	$49.1	Buy
144711	25g	$64	Buy
C1556	10g	$68	Buy
C1556	25g	$132	Buy
B24278	25g	$135.65	Buy

2-Cyanobenzyl bromide Chemical Properties,Uses,Production

Description

2-(Bromomethyl)benzonitrile reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)meth-yl]benzonitrile. It undergoes base-promoted condensation reaction with homophthalic anhydride to yield 6,11-dihydro-5H-indeno[1,2-c]isoquinolin-5-one.

Chemical Properties

White to light yellow crystal powder

Uses

2-(Bromomethyl)benzonitrile is an intermediate in the synthesis of Alogliptin, an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package.

General Description

2-(Bromomethyl)benzonitrile reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)meth-yl]benzonitrile. It undergoes base-promoted condensation reaction with homophthalic anhydride to yield 6,11-dihydro-5H-indeno[1,2-c]isoquinolin-5-one.

Purification Methods

Purify the nitrile by steam distillation. Extract the distillate with Et2O, dry the extract (Na2SO4), evaporate and distil the residue. The solidified distillate can be recrystallised from pet ether or cyclohexane. NMR (CDCl3) : 7.8-7.2 (m 4H), 4.62 (s, 2H), IR max 2238 cm1 . [Drory Chem Ber 24 2570 1891, Borsche et al. Chem Ber 74 685 1934, Buckley et al. Aust J Chem 22 594 1969, Beilstein 9 III 2312.] LACHRYMATORY.

2-Cyanobenzyl bromide Preparation Products And Raw materials

Raw materials

Preparation Products

2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h)-pyriMidinyl)Methyl]benzonitrile 2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE 2-(Hydroxymethyl)benzonitrile Dibenzo[b,e]thiepin-11(6H)-one 2,3-dihydro-1-oxo-1H-indene-4-carbonitrile

2-[(2-formylpyrrol-1-yl)methyl]benzonitrile N-[2-(AMINOMETHYL)BENZYL]-N,N-DIETHYLAMINE 2-Cyanobenzyl acetate 2-(4-HYDROXY-PIPERIDIN-1-YLMETHYL)-BENZONITRILE

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2-Cyanobenzyl bromide Suppliers

Global( 533)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5857	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2472	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	10986	58
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	sales03@chemcn.cn	China	970	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	9210	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Henan Bao Enluo International TradeCo.，LTD	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
hebei hongtan Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Shanghai Yingrui Biopharma Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60

View Lastest Price from 2-Cyanobenzyl bromide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-25	2-Cyanobenzyl bromide 22115-41-9	US $0.00-0.00 / kg	1kg	98%	1 ton	Nanjing Fred Technology Co., Ltd
2024-11-25	2-Cyanobenzyl bromide 22115-41-9	US $42.00 / KG	1KG	99%	100MT	Jinan Finer Chemical Co., Ltd
2024-11-22	2-Cyanobenzyl bromide 22115-41-9	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD

2-Cyanobenzyl bromide
22115-41-9
US $0.00-0.00 / kg
98%
Nanjing Fred Technology Co., Ltd

2-Cyanobenzyl bromide
22115-41-9
US $42.00 / KG
99%
Jinan Finer Chemical Co., Ltd

2-Cyanobenzyl bromide
22115-41-9
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

2-Cyanobenzyl bromide Spectrum

2-Cyanobenzyl bromide(22115-41-9)¹HNMR 2-Cyanobenzyl bromide(22115-41-9)IR 2-Cyanobenzyl bromide(22115-41-9)FT-IR 2-Cyanobenzyl bromide(22115-41-9)Raman

22115-41-9(2-Cyanobenzyl bromide)Related Search:

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2-cyano-5-fluorobenzylbroMide Bromine Methyl bromide

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Adjacent cyano benzyl broMide O-CYANOBENZYL BROMIDE ALPHA-BROMO-O-TOLUONITRILE AKOS 92624 AKOS BBS-00000052 A-BROMO-O-TOLUNITRILE alpha-bromo-ortho-tolunitrile 2-CYANOBENZYL BROMIDE 2-(Bromomethyl)benzonitrile >=97% α-Bromo-o-toluntrile a-Bromo-o-tolunitrile, (2-Cyanobenzyl bromide) ALPHA-BROMO-ORTHO-TOLUNITRILE, 97+% Alpha-Bromo-O-Tolunitrile98% Benzonitrile, 2-(bromomethyl)- à-bromo-o-tolunitrile α-bromo-o-tolunitrile 2-Cyanobenzyl bromide 98% 2-Cyanobenzylbromide98% 2-CYANIDE BENZYL BROMIDE 99+% 2-(Bromomethyl)benzonitrile, 97% - (See B24278) α-Bromo-o-tolunitrile, 2-Cyanobenzyl bromide 2-(bromomethy)benzonitrile 2-(Bromomethyl)benzonitrile,98% α-Bromo-o-tolunitrile ,97% -Cyano benzyl broMide (O-Cyano benzyl broMide) 2-(Bromomethyl)benzonitrile 98% 2-(Bromomethyl)benzonitrile alpha-Bromo-o-tolunitrile o-(Bromomethyl)benzonitrile (2-Cyanophenyl)Methyl broMide 2-Cyanobenzyl bromide 2-(Bromomethyl)benzonitrile o-Cyanobenzyl Bromid 2-(Bromomethyl)Benzonitrile Alogliptin-2 2-CyanobenzylBromide> Cyanobenzyl bromide alogliptin impurities160 alogliptin impurities13 alpha-Bromo-o-tolunitrile,2-Cyano benzyl bromide ALPHA-BROMO-O-TOLUNITRILE 2-(BROMOMETHYL)BENZONITRILE Ortho Cyano Benzyl Bromide 1-Pyrrolidinepropanoicacid,2,11-dioxo- Alpha bromo toluoyl nitrile (2-Cyanophenyl)methyl bromide (Alogliptin Impurity) Alogliptin intermediate 2-Cyanobenzyl bromide 22115-41-9 22115-14-9 2215-41-9 BrCH2C6H4CN Cyanides/Nitriles Organic Building Blocks Nitrogen Compounds C8 to C9 Building Blocks cyanide| alkyl bromide 22115-41-9