AC-5216
- CAS No.
- 226954-04-7
- Chemical Name:
- AC-5216
- Synonyms
- CS-2606;AC-5216;XBD-173;Mapunil;EMapunil;AC-5216,XBD-173;Emapunil(AC-5216);AC 5216 (Emapunil);XBD173 >=98% (HPLC);AC-5216;XBD-173;EMAPUNIL;AC5216;AC 5216
- CBNumber:
- CB32448636
- Molecular Formula:
- C23H23N5O2
- Molecular Weight:
- 401.46
- MDL Number:
- MFCD07772312
- MOL File:
- 226954-04-7.mol
storage temp. | 2-8°C |
---|---|
solubility | DMF: 30 mg/mL; DMF:PBS (pH 7.2) (1:20): 0.05 mg/mL; DMSO: 5 mg/mL |
form | powder |
color | white to beige |
FDA UNII | OG837L732J |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
NFPA 704 |
|
AC-5216 price More Price(20)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML1223 | XBD173 ≥98% (HPLC) | 226954-04-7 | 5MG | $118 | 2024-03-01 | Buy |
Sigma-Aldrich | SML1223 | XBD173 ≥98% (HPLC) | 226954-04-7 | 25MG | $462 | 2024-03-01 | Buy |
Cayman Chemical | 18522 | AC-5216 ≥98% | 226954-04-7 | 1mg | $34 | 2024-03-01 | Buy |
Cayman Chemical | 18522 | AC-5216 ≥98% | 226954-04-7 | 5mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 18522 | AC-5216 ≥98% | 226954-04-7 | 10mg | $183 | 2024-03-01 | Buy |
AC-5216 Chemical Properties,Uses,Production
Uses
Emapunil possesses anxiolytic and antidepressant-like effects and a ligand for translocator protein (TSPO), which plays an important role in the depression treatment.
Biochem/physiol Actions
XBD173 (emapunil, AC-5216) is a potent and selective translocator protein 18 kDa (TSPO) ligand with a Ki value of 0.297 nM. XBD173 acts at the TSPO translocator protein, formerly called the peripheral benzodiazepine receptor, which is involved in production of neuroactive steroids such as allopregnanolone in the brain. TSPO carries cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step of steroidogenesis. XBD173 enhances GABA-mediated neurotransmission via induction of neurosteroidogenesis and exhibits anti-anxiety and antidepressant-like effects.
storage
Store at +4°C
AC-5216 Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32956 | 60 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 11885 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
Chemia Biotechnology(Shanghai) Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9639 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9984 | 58 |