7-ISOPROPYLISATIN

CAS No.
57816-97-4
Chemical Name:
7-ISOPROPYLISATIN
Synonyms
7-ISOPROPYLISATIN;UKRORGSYN-BB BBV-030970;7-Isopropylindoline-2,3-dione;7-(1-Methylethyl)-1H-indole-2,3-dione;1H-Indole-2,3-dione, 7-(1-methylethyl)-
CBNumber:
CB32449855
Molecular Formula:
C11H11NO2
Molecular Weight:
189.21
MDL Number:
MFCD09737499
MOL File:
57816-97-4.mol
Last updated:2023-04-13 16:42:53

7-ISOPROPYLISATIN Properties

Melting point 196-198 °C(Solv: dichloromethane (75-09-2))
Density 1.200±0.06 g/cm3(Predicted)
pka 9.81±0.20(Predicted)
InChI InChI=1S/C11H11NO2/c1-6(2)7-4-3-5-8-9(7)12-11(14)10(8)13/h3-6H,1-2H3,(H,12,13,14)
InChIKey XWJSENVAAAAHBN-UHFFFAOYSA-N
SMILES N1C2=C(C=CC=C2C(C)C)C(=O)C1=O

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

7-ISOPROPYLISATIN price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC I873468 7-Isopropyl-1H-indole-2,3-dione 57816-97-4 50mg $55 2021-12-16 Buy
TRC I873468 7-Isopropyl-1H-indole-2,3-dione 57816-97-4 500mg $275 2021-12-16 Buy
American Custom Chemicals Corporation CHM0384086 7-ISOPROPYLISATIN 95.00% 57816-97-4 5MG $504.61 2021-12-16 Buy
AK Scientific 4708CT 7-Isopropylindoline-2,3-dione 57816-97-4 2.5g $853 2021-12-16 Buy
Matrix Scientific 177953 7-Isopropyl-1H-indole-2,3-dione 57816-97-4 0.500g $160 2021-12-16 Buy
Product number Packaging Price Buy
I873468 50mg $55 Buy
I873468 500mg $275 Buy
CHM0384086 5MG $504.61 Buy
4708CT 2.5g $853 Buy
177953 0.500g $160 Buy

7-ISOPROPYLISATIN Chemical Properties,Uses,Production

Uses

7-Isopropyl-1H-indole-2,3-dione is used in the synthetic preparation of 2-aminoquinazoline derivatives as PLK1 inhibitor useful in treatment of various diseases.

Synthesis

To concentrated sulfuric acid at 80° C. was added 2-hydroxyimino-N-(2-isopropyl-phenyl)-acetamide in several small portions over 10 minutes. After addition it was heated at 80° C. for 30 minutes., then poured into ice. Filtration, washing with water, and drying under vacuum over P2O5 provided 2.974 g (84%) of 7-Isopropyl-1H-indole-2,3-dione as a solid. 
synthesis of 7-Isopropyl-1H-indole-2,3-dione

7-ISOPROPYLISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

7-ISOPROPYLISATIN Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
Energy Chemical 021-021-58432009 400-005-6266 sales8178@energy-chemical.com China 44700 61
Shanghai ChuangYan Chemical Technology Co., Ltd. 021-11111111 11111111111 546919421@qq.com China 3075 55
Aikon International Limited 025-66113011 18112977050 sales01@aikonchem.com China 16028 58
Shanghai WangFa Chemical Technology Co., Ltd. 13918479294 xiebenfa@163.com China 3351 58
Changzhou Kechem Bio-Scientific Co., LTD. 0519-68985668 13685222090 sales@kechem.cn China 26033 58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd 2383948258 19172820304 2383948258@qq.com China 12994 58
Hefei Mokai Pharmaceutical Technology Co., Ltd 18130062233 3362556465@qq.com China 8000 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 63720 58
Heze Aiding Pharmaceutical Co., Ltd 17661365138 2845578351@qq.com China 7100 58
Shanghai Jieshikai Biotechnology Co. , Ltd. 021-57520305 15026420323 guojianing@jskchem.com China 49242 58
UKRORGSYN-BB BBV-030970 7-ISOPROPYLISATIN 7-Isopropylindoline-2,3-dione 1H-Indole-2,3-dione, 7-(1-methylethyl)- 7-(1-Methylethyl)-1H-indole-2,3-dione 57816-97-4