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Slv320

CAS No.
251945-92-3
Chemical Name:
Slv320
Synonyms
Slv320;SC-204288;Derenofylline;SLV320 >=98% (HPLC);SLV320; SLV-320; SLV 320; DERENOFYLLINE;4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol;4-[(2-phenyl-7H-pyrrolo[2, 3-d]pyrimidin-4-yl)amino]cyclohexan-1-ol;(1R,4R)-4-(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanol;trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol;Cyclohexanol, 4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-, trans-
CBNumber:
CB32492503
Molecular Formula:
C18H20N4O
Molecular Weight:
308.38
MDL Number:
MOL File:
251945-92-3.mol
Last updated:2024-11-19 23:02:33

Slv320 Properties

Boiling point 532.3±60.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Soluble to 100 mM in DMSO and to 50 mM in ethanol
form Powder
pka 15.15±0.40(Predicted)
color White to off-white
FDA UNII O1Q96UZ63W

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

Slv320 price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27666 Derenofylline 251945-92-3 5mg $92 2024-03-01 Buy
Cayman Chemical 27666 Derenofylline 251945-92-3 25mg $371 2024-03-01 Buy
Cayman Chemical 27666 Derenofylline 251945-92-3 1mg $34 2024-03-01 Buy
Cayman Chemical 27666 Derenofylline 251945-92-3 10mg $166 2024-03-01 Buy
Tocris 3344 SLV320 ≥99%(HPLC) 251945-92-3 10 $181 2021-12-16 Buy
Product number Packaging Price Buy
27666 5mg $92 Buy
27666 25mg $371 Buy
27666 1mg $34 Buy
27666 10mg $166 Buy
3344 10 $181 Buy

Slv320 Chemical Properties,Uses,Production

Description

Derenofylline is an adenosine A1 receptor antagonist (Ki = 1 nM). It is selective for adenosine A1 over A2A, A2B, and A3 receptors (Kis = 398, 3,981, and 200 nM, respectively). It decreases adenosine A1 receptor-mediated adenosine-induced bradycardia in rats (ED50 = 0.49 mg/kg) but reduces A2 receptor-mediated adenosine-induced hypotension by only 44.6% when administered at an intravenous dose of 5 mg/kg. It prevents increases in heart levels of collagen I and III in nephrectomized rats when administered at a dose of 10 mg/kg per day. Derenofylline also reduces relative plaque counts in a Zika virus plaque-forming assay in A549 cells (IC50 = 58.6 nM) in an adenosine A1 receptor-independent manner without inducing cytotoxicity when used at concentrations less than 10 μM.

Uses

SLV 320 is an A1 antagonist.

Slv320 Preparation Products And Raw materials

Raw materials

Preparation Products

Slv320 Suppliers

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30239 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58

View Lastest Price from Slv320 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Derenofylline pictures 2024-11-19 Derenofylline
251945-92-3
US $42.00-152.00 / mg 98.09% 10g TargetMol Chemicals Inc.
  • Derenofylline pictures
  • Derenofylline
    251945-92-3
  • US $42.00-152.00 / mg
  • 98.09%
  • TargetMol Chemicals Inc.
Cyclohexanol, 4-((2-phenyl-1H-pyrrolo(2,3-D)pyrimidin-4-yl)amino)-, trans- Slv320 trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol (1R,4R)-4-(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanol SC-204288 Derenofylline 4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol SLV320; SLV-320; SLV 320; DERENOFYLLINE Cyclohexanol, 4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-, trans- SLV320 >=98% (HPLC) rel-(1r,4r)-4-((2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexan-1-ol Inhibitor,P1 receptor,Derenofylline,Adenosine Receptor,SLV320,fibrosis,uraemic,SLV-320,cardiomyopathy,SLV 320,inhibit,Nephrectomy 4-[(2-phenyl-7H-pyrrolo[2, 3-d]pyrimidin-4-yl)amino]cyclohexan-1-ol 251945-92-3