Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate
- CAS No.
- 473927-63-8
- Chemical Name:
- Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate
- Synonyms
- Apixaban I;Apixaban int;Apixaban Impurity O;Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]acetate;Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate;Acetic acid, chloro[(4-methoxyphenyl)hydrazono]-, ethyl este...;Ethyl (2Z)-2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene]acetate;ethyl (2Z)-2-chloro-2-[2-(4-methoxyphenyl)hydrazin-1-ylidene]acetate;Acetic acid, chloro[(4-Methoxyphenyl)hydrazono]-, ethyl ester, (2Z)-;(2Z)-2-Chloro-2-[2-(4-methoxyphenyl)hydrazinylidene]acetic acid ethyl ester
- CBNumber:
- CB32514108
- Molecular Formula:
- C11H13ClN2O3
- Molecular Weight:
- 256.69
- MDL Number:
- MOL File:
- 473927-63-8.mol
- MSDS File:
- SDS
Boiling point | 349.0±44.0 °C(Predicted) |
---|---|
Density | 1.23 |
vapor pressure | 0.008Pa at 25℃ |
pka | 11.63±0.10(Predicted) |
InChI | InChI=1S/C11H13ClN2O3/c1-3-17-11(15)10(12)14-13-8-4-6-9(16-2)7-5-8/h4-7,13H,3H2,1-2H3/b14-10- |
InChIKey | ATNPZEGMKLGIFA-UVTDQMKNSA-N |
SMILES | C(OCC)(=O)/C(/Cl)=N/NC1=CC=C(OC)C=C1 |
LogP | 2.53 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06,GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H301-H311-H331-H341 |
Precautionary statements | P201-P202-P261-P264-P270-P271-P280-P302+P352-P304+P340-P308+P313-P310-P330-P361-P403+P233-P405-P501 |
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Crysdot | CD12069983 | (Z)-Ethyl2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 95+% | 473927-63-8 | 5g | $360 | 2021-12-16 | Buy |
Alichem | 473927638 | (Z)-Ethyl2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate | 473927-63-8 | 10g | $523.8 | 2021-12-16 | Buy |
Crysdot | CD12069983 | (Z)-Ethyl2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 95+% | 473927-63-8 | 10g | $540 | 2021-12-16 | Buy |
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate Chemical Properties,Uses,Production
Uses
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development and chemical and pharmaceutical production processes.
Synthesis
Preparation of ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate To p-anisidine (16 g, 0.129 mol) in conc. HCL (40 mL), 100 mL) H2O, cooled to -5?? C. and sodium nitrite (9.4 g, 0.136 mol) in H2O (60 mL) was added. The reaction mixture was stirred at -5?? C. for 20 min and a mixture of ethylchloroacetoacetate (22 g, 0.133 mol), ethanol (100 mL), sodiumacetate (32 g, 0.389 mmol), and H2O (400 mL) was added. The reaction was allowed to warm up to room temperature and stirred for 2h. The product precipitated as a black solid. It was filtered and dried (30 g). 1H-NMR (CDCl3) |? 8.28 (s, 1H), 7.18 (d, 2H), 6.90 (d, 2H), 4.41 (q, 2H), 3.80 (s, 3H), 1.42 (t, 3H) ppm.
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Jinan Million Pharmaceutical Co., Ltd | 0531-68659554 +8613031714605 | info@millionpharm.com | China | 213 | 58 |
Jinan Jianfeng Chemical Co., Ltd | +8615562555968 | info@pharmachemm.com | China | 247 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18656 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 801 | 55 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2965 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
Shenzhen Excellent Biotech Co., Ltd. | 13480692018 | ramyan@ex-biotech.com | CHINA | 954 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49403 | 58 |
View Lastest Price from Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-18 | Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate
473927-63-8
|
US $2.00 / kg | 1kg | 99% | 1200KG/M | Jinan Million Pharmaceutical Co., Ltd | ||
2024-10-18 | Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate
473927-63-8
|
US $30.00 / KG | 1KG | 99% | 300MT/year | Speranza Chemical Co., Ltd. | ||
2019-12-20 | Ethyl(2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate
473927-63-8
|
US $1.00 / g | 1g | 99% | g/kg/T | Career Henan Chemical Co |
- Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate
473927-63-8
- US $2.00 / kg
- 99%
- Jinan Million Pharmaceutical Co., Ltd
- Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate
473927-63-8
- US $30.00 / KG
- 99%
- Speranza Chemical Co., Ltd.
- Ethyl(2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate
473927-63-8
- US $1.00 / g
- 99%
- Career Henan Chemical Co
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