ChemicalBook >> CAS DataBase List >>3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
- CAS No.
- 881386-01-2
- Chemical Name:
- 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
- Synonyms
- Apixaban Impurity 65;Apixaban Impurity 60;RRSYY(Fasoracetam)-4;3,3-dichloro-1-(4-nitrophenyl)piperidin-2-one;3,3-Dichloro-1-(4-nitrophenyl)-2-piperidinone;3,3-dichloro-1-(4-nitrophenyl)2-2-piperidinone;2-Piperidinone, 3,3-dichloro-1-(4-nitrophenyl)-;2-Piperidinone, 3,3-dichloro-1-(4-nitrophenyl)-,881386-01-2;3,3-Dichloro-1-(4-Nitrophenyl)piperidin-2-one2-Piperidinone, 3,3-dichloro-1-(4-nitrophenyl);3,3-dichloro-1-(4-nitrophenyl)piperidin-2-one 3,3-dichloro-1-(4-nitrophenyl)piperidin-2-one
- CBNumber:
- CB92594346
- Molecular Formula:
- C11H10Cl2N2O3
- Molecular Weight:
- 289.11
- MDL Number:
- MFCD23142941
- MOL File:
- 881386-01-2.mol
Last updated:2023-08-15 17:37:19
Boiling point | 520.2±50.0 °C(Predicted) |
---|---|
Density | 1.50 |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly, Sonicated) |
form | Solid |
pka | -7.38±0.40(Predicted) |
color | Light Yellow to Yellow |
InChI | InChI=1S/C11H10Cl2N2O3/c12-11(13)6-1-7-14(10(11)16)8-2-4-9(5-3-8)15(17)18/h2-5H,1,6-7H2 |
InChIKey | KKVYXBZVPRSWHE-UHFFFAOYSA-N |
SMILES | N1(C2=CC=C([N+]([O-])=O)C=C2)CCCC(Cl)(Cl)C1=O |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-M2357 | 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one 99.73% | 881386-01-2 | 10g | $50 | 2021-12-16 | Buy |
Ambeed | A985233 | 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one 97% | 881386-01-2 | 25g | $67 | 2021-12-16 | Buy |
aablocks | AA00GTWP | 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one 98% | 881386-01-2 | 10g | $87 | 2021-12-16 | Buy |
Crysdot | CD11035802 | 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one 97% | 881386-01-2 | 5g | $90 | 2021-12-16 | Buy |
aablocks | AA00GTWP | 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one 98% | 881386-01-2 | 25g | $127 | 2021-12-16 | Buy |
3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one Chemical Properties,Uses,Production
Physical Form
Light Yellow to Yellow Solid
Description
3, 3-dichloro-1 -(4-nitrophenyl) -2-piperidinone is an important pharmaceutical intermediate, as it can be used to prepare apixaban derivatives. Apixaban is a small molecular selective FXa inhibitor of pyrazole derivatives. Similar to Rivaroxaban, apixaban has two binding sites to Factor Xa, where 4-methoxyphenyl in the apixaban structure partially binds the S1 pocket of Factor Xa and aryllactam partially binds the S4 pocket of Factor Xa.
Uses
3,??3-??Dichloro-??1-??(4-??nitrophenyl)??piperidin-??2-??one is a reagent used in the preparation of novel tetrahydropyrazolopyridone derivatives. Used in the preparation of anti-coagulants.
3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 134)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Jinan Million Pharmaceutical Co., Ltd | 0531-68659554 +8613031714605 | info@millionpharm.com | China | 200 | 58 |
Jinan Jianfeng Chemical Co., Ltd | +8615562555968 | info@pharmachemm.com | China | 243 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Jinan Chenghui-Shuangda Chemical Co.,Ltd | +86-531-58897082 | ericqiao@jnchsd.com | CHINA | 158 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
Synbest Biotech(Hangzhou) Co., Ltd | 86-571-88737065 | sales@synbestech.com | CHINA | 171 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
View Lastest Price from 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-08-23 | 2-Piperidinone, 3,3-dichloro-1-(4-nitrophenyl)-
881386-01-2
|
US $20.00 / KG | 1KG | 98% | 20 tons | Speranza Chemical Co., Ltd. | |
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2024-08-23 | 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
881386-01-2
|
US $2.00 / kg | 1kg | 99% | 1200KG/M | Jinan Million Pharmaceutical Co., Ltd | |
![]() |
2022-10-01 | 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
881386-01-2
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 2-Piperidinone, 3,3-dichloro-1-(4-nitrophenyl)-
881386-01-2
- US $20.00 / KG
- 98%
- Speranza Chemical Co., Ltd.
-
- 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
881386-01-2
- US $2.00 / kg
- 99%
- Jinan Million Pharmaceutical Co., Ltd
-
- 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
881386-01-2
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
881386-01-2(3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one)Related Search:
Apixaban Impurity 16
(4,4'‐didodecyl‐2,2'‐
bithiophene‐5,5'‐
diyl)bis(triMethylstann
ane)
Apixaban-13C-D3
Apixaban IMpurity 5 (BMS-591329-01)
Apixaban IMpurity(BMS-778960-01)
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate
1-(4-Methoxyphenyl)-6-(4-iodophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
1-(4-Methoxyphenyl)-6-(4-(2-Methyl-6-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxaMide
1of4
3,3-Dichloro-1-(4-nitrophenyl)-2-piperidinone
3,3-dichloro-1-(4-nitrophenyl)piperidin-2-one
3,3-dichloro-1-(4-nitrophenyl)piperidin-2-one
3,3-dichloro-1-(4-nitrophenyl)piperidin-2-one
2-Piperidinone, 3,3-dichloro-1-(4-nitrophenyl)-
Apixaban Impurity 60
Apixaban Impurity 65
3,3-dichloro-1-(4-nitrophenyl)2-2-piperidinone
2-Piperidinone, 3,3-dichloro-1-(4-nitrophenyl)-,881386-01-2
RRSYY(Fasoracetam)-4
3,3-Dichloro-1-(4-Nitrophenyl)piperidin-2-one2-Piperidinone, 3,3-dichloro-1-(4-nitrophenyl)
881386-01-2