ChemicalBook >> CAS DataBase List >>1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester

1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester

CAS No.
503614-91-3
Chemical Name:
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
Synonyms
Apixaban Ester Impurity;Apixaban Ethyl ester Impurity;1H-Pyrazolo[3,4-c]pyridine-3-carboxylicacid,4,5,6,7-tetrahydro-1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-,ethylester;TECO-008;FaX-IN-1;Apixaban V;Apixaban-3;BMS-589154);Apixaban N-1;BMS-589154))
CBNumber:
CB32516218
Molecular Formula:
C27H28N4O5
Molecular Weight:
488.54
MDL Number:
MFCD18072444
MOL File:
503614-91-3.mol
MSDS File:
SDS
Last updated:2024-11-17 08:48:38

1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester Properties

Melting point 175 - 180°C
Boiling point 758.7±60.0 °C(Predicted)
Density 1.34
vapor pressure 0.001Pa at 25℃
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
pka 0.78±0.20(Predicted)
form Solid
color White to Pale Beige
InChI InChI=1S/C27H28N4O5/c1-3-36-27(34)24-22-15-17-30(19-9-7-18(8-10-19)29-16-5-4-6-23(29)32)26(33)25(22)31(28-24)20-11-13-21(35-2)14-12-20/h7-14H,3-6,15-17H2,1-2H3
InChIKey PULNLYVCJSOXKS-UHFFFAOYSA-N
SMILES C1(=O)N(C2=CC=C(N3CCCCC3=O)C=C2)CCC2C(C(OCC)=O)=NN(C3=CC=C(OC)C=C3)C1=2
LogP 172 at 22.8℃
FDA UNII Q9LMP4ZJ6N

SAFETY

Risk and Safety Statements

Hazard statements  H412
Precautionary statements  P273-P501

1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A726710 ApixabanV 503614-91-3 100mg $65 2021-12-16 Buy
ChemScene CS-M3061 ethyl1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 99.65% 503614-91-3 10g $91 2021-12-16 Buy
AK Scientific X5908 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylicacidethylester 503614-91-3 5g $135 2021-12-16 Buy
ChemScene CS-M3061 ethyl1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 99.65% 503614-91-3 25g $183 2021-12-16 Buy
AK Scientific X5908 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylicacidethylester 503614-91-3 25g $303 2021-12-16 Buy
Product number Packaging Price Buy
A726710 100mg $65 Buy
CS-M3061 10g $91 Buy
X5908 5g $135 Buy
CS-M3061 25g $183 Buy
X5908 25g $303 Buy

1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester Chemical Properties,Uses,Production

Uses

Apixaban V is a derivative of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation

545445-44-1
27143-07-3
503614-91-3
Synthesis of 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester from 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one and Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate

1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 304)Suppliers
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Jinan Jianfeng Chemical Co., Ltd
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PT CHEM GROUP LIMITED
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hebei hongtan Biotechnology Co., Ltd
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Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester pictures 2024-12-25 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
503614-91-3
US $2.00 / kg 1kg 99% 1200KG/M Jinan Million Pharmaceutical Co., Ltd
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester pictures 2024-12-25 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
503614-91-3
US $25.00 / KG 1KG 98% 20 tons Speranza Chemical Co., Ltd.
Apixaban Intermediate 4,5,6,7 pictures 2024-12-24 Apixaban Intermediate 4,5,6,7
503614-91-3
US $30.00 / kg 1kg 99% 2000kg hebei hongtan Biotechnology Co., Ltd
ethyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate -4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate -7-oxo-6-(4-(2-oxopiperidin-1-yl) Ethyl 1-(4-methoxyphenyl) Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazo 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester 4,5,6,7-Tetrahydro-1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1h-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester Apixaba inretMediate C 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester Apixaban V 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid e BMS-589149-01 Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[ ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H- Apixaban-3 Apixaban Ethyl Ester Imp Apixaban N-1 Apixaban Impurity C ethyl ApixabanIm purit 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4 4-c]pyridine-3-carboxylic acid ethyl ester Impurity of apixaban381 Apixaban Intermediate 4,5,6,7 1H-Pyrazolo[3,4-c]pyridine-3-carboxylicacid,4,5,6,7-tetrahydro-1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-,ethylester Apixaban Ethyl ester Impurity Apixaban Ester Impurity TECO-008 1-(4-Methoxyphenyl)-7-oxo -6-[4-(2-oxopiperidin-1-yl) phenyl]-4,5,6,7-tetrahydro- 1H-pyrazolo[3,4-c]pyridine -3-carboxylic acid ethyl este Apixaban Impurity BZ Apixaban Impurity 9 (BMS-589149-01) BMS-589154) BMS-589154)) Apixaban INT 02 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyr Apixaban ethyl ester impuity Ethyl 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1- yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3- carboxylate Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1yl)phenyl)-4,5,6,7-tetrahydro-1H- pyrozolo[3,4-c] pyridine-3-carboxylate 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo FaX-IN-1 Ethyl 1-(4-Methoxyphenyl)-7-Oxo-6-(4-(2-Oxopiperidin-1-Yl 503614-91-3 API