STAT5 Inhibitor
- CAS No.
- 285986-31-4
- Chemical Name:
- STAT5 Inhibitor
- Synonyms
- MDK6314;CS-2509;STAT5-IN-1;STAT5 Inhibitor;STAT5 Inhibitor 1;Stat5 Inhibitor(STAT5-IN-1);N'-[(4-oxo-4H-chromen-3-yl)methylene]nicotinohydrazide;STAT-5-IN-1,STAT5IN1,inhibit,STAT5 IN 1,Inhibitor,STAT;N'-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide;(E)-N'-((4-oxo-4H-chromen-3-yl)methylene)nicotinohydrazide
- CBNumber:
- CB32515923
- Molecular Formula:
- C16H11N3O3
- Molecular Weight:
- 293.28
- MDL Number:
- MFCD00124694
- MOL File:
- 285986-31-4.mol
STAT5 Inhibitor price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 573108-M | STAT5 Inhibitor - CAS 285986-31-4 - Calbiochem The STAT5 Inhibitor, also referenced under CAS 285986-31-4, controls the biological activity of STAT5. | 285986-31-4 | 10MG | $148 | 2024-03-01 | Buy |
| Cayman Chemical | 15784 | STAT5 Inhibitor ≥95% | 285986-31-4 | 5mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 15784 | STAT5 Inhibitor ≥95% | 285986-31-4 | 10mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 15784 | STAT5 Inhibitor ≥95% | 285986-31-4 | 25mg | $286 | 2024-03-01 | Buy |
| ApexBio Technology | C4105 | STAT5Inhibitor | 285986-31-4 | 25mg | $324 | 2021-12-16 | Buy |
STAT5 Inhibitor Chemical Properties,Uses,Production
Description
Signal Transducers and Activators of Transcriptions (STATs) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. STAT5, which consists of two isoforms STAT5α and STAT5β, is known to be overactive in several kinds of leukemias and various solid tumors. STAT5 Inhibitor is a cell-
Uses
2-?[(4-?Oxo-?4H-?1-?benzopyran-?3-?yl)?methylene]?hydrazide-3-?pyridinecarboxylic Acid is a selective inhibitor of STAT5.
Definition
ChEBI: A carbohydrazide that is nicotinohydrazide in which the terminal nitrogen has undergone formal condensation with the aldehyde group of 4-oxo-4H-chromene-3-carbaldehyde. It is an inhibitor of STAT5 (Signal Transducer and Activator of Tran cription 5) protein.
References
[1]. müller j, sperl b, reindl w, et al. discovery of chromone-based inhibitors of the transcription factor stat5. chembiochem. 2008 mar 25;9(5):723-7.
[2]. leonard wj, o'shea jj. jaks and stats: biological implications. annu rev immunol. 1998;16:293-322.
[3]. schindler c, darnell je jr. transcriptional responses to polypeptide ligands: the jak-stat pathway. annu rev biochem. 1995;64:621-51.
STAT5 Inhibitor Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32956 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30238 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5221 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |