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Shikalkin

Shikalkin structure

CAS No.: 54952-43-1

Chemical Name:: Shikalkin

Synonyms: shiconin;Arnebin-4;SHIKALKIN;Nsc 291845;(+-)-Shikonin;(Rac)-Shikonin;Shikonin >=98% (HPLC);Shikonin (mixture of optical isomers, about 1:1);5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione;5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione

CBNumber:: CB3273506

Molecular Formula:: C16H16O5

Molecular Weight:: 288.3

MDL Number:: MFCD00016668

MOL File:: 54952-43-1.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

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Shikalkin Properties

Melting point	144-145 °C
Boiling point	567.4±50.0 °C(Predicted)
Density	1.373±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	methanol: soluble1mg/mL
pka	7.34±0.20(Predicted)
form	powder or solid
color	red to brown
LogP	4.350 (est)
UNSPSC Code	12352200
NACRES	NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Signal word

Warning

Hazard statements

H302-H400

Precautionary statements

P273-P301+P312+P330

Hazard Codes

Xn,N

Risk Statements

22-50/53

Safety Statements

RIDADR

UN 3077 9 / PGIII

WGK Germany

NFPA 704

	0
2		0

Shikalkin price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S7576	Shikonin ≥98% (HPLC)	54952-43-1	10mg	$473	2024-03-01	Buy
Sigma-Aldrich	S7576	Shikonin ≥98% (HPLC)	54952-43-1	50mg	$1620	2024-03-01	Buy
TRC	S357605	(±)-Shikonin	54952-43-1	5mg	$85	2021-12-16	Buy
AK Scientific	0282AQ	Shikonin	54952-43-1	10mg	$162	2021-12-16	Buy
Arctom	SY232843	(±)-Shikonin ≥98%	54952-43-1	10mg	$74.45	2021-12-16	Buy

Product number	Packaging	Price	Buy
S7576	10mg	$473	Buy
S7576	50mg	$1620	Buy
S357605	5mg	$85	Buy
0282AQ	10mg	$162	Buy
SY232843	10mg	$74.45	Buy

Shikalkin Chemical Properties,Uses,Production

Uses

Shikonin has been used:

to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells
as an inhibitor of renal aerobic glycosis and a potential
as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction
to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death

Definition

ChEBI: C.I. Natural Red 20 is a naphthoquinone.

General Description

Shikonin is a major phytochemical compound extracted from the roots of Lithospermum erythrorhizon. It is a natural anthraquinone derivative.

Biochem/physiol Actions

Shikonin is a potent anti-fungal agent against C. albicans biofilms. It displays anti-oxidant and chemotherapeutic properties on human glioma cells.

Shikalkin Preparation Products And Raw materials

Raw materials

Preparation Products

Shikalkin Suppliers

Global( 71)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	997	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	sales@dogechemical.com	China	4128	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	+8618829768577	gao490372054@gamil.com	China	1249	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Henan Allgreen Chemical Co.,LTD	+86-37155567971 +86-13633837469	info@allgreenchem.com	China	5996	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58

Supplier	Advantage
Shaanxi Haibo Biotechnology Co., Ltd	58
Shanghai Standard Technology Co., Ltd.	58
Wuhan ChemNorm Biotech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Nanjing Doge Biomedical Technology Co., Ltd	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Henan Allgreen Chemical Co.,LTD	58
LEAPCHEM CO., LTD.	58

View Lastest Price from Shikalkin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-19	(±)-Shikonin 54952-43-1	US $70.00-48.00 / mg		99.73%	10g	TargetMol Chemicals Inc.
2024-04-12	Shikalkin 54952-43-1	US $0.00 / kg	1kg	99%	2000ton	Shaanxi Haibo Biotechnology Co., Ltd
2023-02-24	Shikalkin 54952-43-1	US $0.00 / mg	5mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.

(±)-Shikonin
54952-43-1
US $70.00-48.00 / mg
99.73%
TargetMol Chemicals Inc.

Shikalkin
54952-43-1
US $0.00 / kg
99%
Shaanxi Haibo Biotechnology Co., Ltd

Shikalkin
54952-43-1
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

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5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione SHIKALKIN 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)- (9ci) Arnebin-4 Nsc 291845 shiconin Shikonin (mixture of optical isomers, about 1:1) 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-penten-1-yl)- Shikonin >=98% (HPLC) (+-)-Shikonin (Rac)-Shikonin 5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione Inhibitor,inhibit,Shikalkin,(Rac) Shikonin,(Rac)Shikonin,(Rac)-Shikonin 54952-43-1 Inhibitors Coronavirus