SPERMINE TETRAHYDROCHLORIDE
- CAS No.
- 306-67-2
- Chemical Name:
- SPERMINE TETRAHYDROCHLORIDE
- Synonyms
- NEURIDINE HYDROCHLORIDE;MUSCULAMINE HYDROCHLORIDE;Spermidine Tetrahydrochloride;Spermine4HCl;SPERMINE HCL;SperMine tetra;Spermidine 4HCl;Spermine, TetraHCl;Spermine-[2H8].4HCl;4-BUTANEDIAMINE 4 HCL
- CBNumber:
- CB3275333
- Molecular Formula:
- C10H30Cl4N4
- Molecular Weight:
- 348.18
- MDL Number:
- MFCD00012914
- MOL File:
- 306-67-2.mol
- MSDS File:
- SDS
Melting point | 310-311 °C (dec.)(lit.) |
---|---|
Density | 1.01 g/mL at 20 °C |
storage temp. | room temp |
solubility | H2O: 1 M at 20 °C, clear, colorless |
form | powder |
color | White to Almost white |
PH | 4.5-7.0 (25℃, 1M in H2O) |
Water Solubility | Soluble in water (348.2 g/L at 20°C). |
λmax |
λ: 260 nm Amax: 0.2 λ: 280 nm Amax: 0.15 |
BRN | 3911771 |
InChI | InChI=1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H |
InChIKey | XLDKUDAXZWHPFH-UHFFFAOYSA-N |
SMILES | C(CNCCCN)CCNCCCN.Cl.Cl.Cl.Cl |
CAS DataBase Reference | 306-67-2(CAS DataBase Reference) |
FDA UNII | 9CI1570O48 |
EPA Substance Registry System | Spermine tetrahydrochloride (306-67-2) |
SPERMINE TETRAHYDROCHLORIDE price More Price(43)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 5677 | Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem | 306-67-2 | 5G | $318 | 2024-03-01 | Buy |
TCI Chemical | B1468 | N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride >98.0%(N)(T) | 306-67-2 | 5g | $178 | 2024-03-01 | Buy |
TCI Chemical | B1468 | N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride >98.0%(N)(T) | 306-67-2 | 25g | $827 | 2024-03-01 | Buy |
Alfa Aesar | J63060 | Spermine tetrahydrochloride, 99% | 306-67-2 | 1g | $35.6 | 2024-03-01 | Buy |
Alfa Aesar | J63060 | Spermine tetrahydrochloride, 99% | 306-67-2 | 5g | $132 | 2024-03-01 | Buy |
SPERMINE TETRAHYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
White to off-white powder
Uses
Used to precipitate DNA from low salt aqueous buffers.
Uses
Spermine tetrahydrochloride was used to precipitate DNA for flow cytometric analysis from fresh frozen breast cancer tissue, archival tissue of salivary gland, renal and thyroid tumors and red blood cells of chicken.
Uses
Spermine Tetrahydrochloride is an inhibitor of NOS1, NMDA, GluR, and PLCα. A useful reactant for Surface-?enhanced Raman spectroscopy (SERS) characterization of abasic sites in DNA duplexes.
Biological Activity
Polyamine which produces a variety of modulatory effects on the NMDA receptor channel, acting through a specific site on the complex which can cause both agonist and antagonist effects.
Biochem/physiol Actions
Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
storage
Desiccate at +4°C
Purification Methods
Its pK values are similar to those of spermidine above. Purify it as for spermidine trihydrochloride above. [Beilstein 4 IV 1301.]
SPERMINE TETRAHYDROCHLORIDE Preparation Products And Raw materials
SPERMINE TETRAHYDROCHLORIDE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
PNP Biotech Co. Ltd | +8618516098983 | sales@pnpbiotech.com | China | 1001 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5857 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18148 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3009 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20274 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 1169 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
View Lastest Price from SPERMINE TETRAHYDROCHLORIDE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2025-01-07 | Spermine tetrahydrochloride
306-67-2
|
US $0.00-0.00 / box | 1box | 99.99% | 1000 | Shandong Huizhihan Supply Chain Co., Ltd | ||
2024-11-19 | Spermine tetrahydrochloride
306-67-2
|
US $41.00 / mg | 99.82% | 10g | TargetMol Chemicals Inc. | |||
2024-10-28 | Spermine Tetrahydrochloride
306-67-2
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd |
- Spermine tetrahydrochloride
306-67-2
- US $0.00-0.00 / box
- 99.99%
- Shandong Huizhihan Supply Chain Co., Ltd
- Spermine tetrahydrochloride
306-67-2
- US $41.00 / mg
- 99.82%
- TargetMol Chemicals Inc.
- Spermine Tetrahydrochloride
306-67-2
- US $0.00-0.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
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