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BC 11-38

BC 11-38 structure

CAS No.: 686770-80-9

Chemical Name:: BC 11-38

Synonyms: 6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one;3-phenyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one;Thieno[3,2-d]pyrimidin-4(3H)-one, 6,7-dihydro-3-phenyl-2-(propylthio)-;cortisol,adrenocortical,Phosphodiesterase (PDE),cAMP,BC 11 38,Inhibitor,production,inhibit,levels,cells,BC11-38,BC 1138

CBNumber:: CB33037165

Molecular Formula:: C15H16N2OS2

Molecular Weight:: 304.43

MDL Number:

MOL File:: 686770-80-9.mol

Last updated:2023-05-18 11:31:06

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BC 11-38 Properties

storage temp.	RT
solubility	Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 14 mg/ml with warming).
form	solid
color	White
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

BC 11-38 price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	20167	BC-11-38 ≥98%	686770-80-9	5mg	$68	2024-03-01	Buy
Cayman Chemical	20167	BC-11-38 ≥98%	686770-80-9	10mg	$109	2024-03-01	Buy
Cayman Chemical	20167	BC-11-38 ≥98%	686770-80-9	25mg	$252	2024-03-01	Buy
TRC	B129345	BC11-38	686770-80-9	25mg	$285	2021-12-16	Buy
ApexBio Technology	B7673	BC11-38	686770-80-9	10mg	$291	2021-12-16	Buy

Product number	Packaging	Price	Buy
20167	5mg	$68	Buy
20167	10mg	$109	Buy
20167	25mg	$252	Buy
B129345	25mg	$285	Buy
B7673	10mg	$291	Buy

BC 11-38 Chemical Properties,Uses,Production

Description

BC-11-38 (686770-80-9) is a? potent and selective inhibitor of phosphodiesterase PDE11 (IC50=0.28 μM).1? IC50s for PDE1-10 are greater than 100 μM. Restores the ability of p54nrb / NONOKD cells to generate cAMP in response to ACTH stimulation and the production of cortisol and DHEA in response to cAMP signaling.2

Uses

BC 11-38 is a selective inhibitor of phosphodiesterase 11. Potent PDE-11 inhibitor

References

1) Ceyhan et al. (2012), Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen; Chem. Biol., 19 155 2) Lu and Sewer (2015), p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation; Mol. Cell. Biol. 35 1223

BC 11-38 Preparation Products And Raw materials

Raw materials

Preparation Products

BC 11-38 Suppliers

Global( 27)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Pharmacodia (Beijing) Co.,Ltd	+86-400-851-9921	sales@pharmacodia.com	China	2317	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9707	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3717	55
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4587	58
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4381	58
BOC Sciences	--	info@bocsci.com	USA	0	65

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
EMMX Biotechnology LLC	60
Pharmacodia (Beijing) Co.,Ltd	55
Shanghai EFE Biological Technology Co., Ltd.	58
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Lynnchem	58
Novachemistry	58
BOC Sciences	65

686770-80-9(BC 11-38)Related Search:

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3-phenyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one 6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one Thieno[3,2-d]pyrimidin-4(3H)-one, 6,7-dihydro-3-phenyl-2-(propylthio)- cortisol,adrenocortical,Phosphodiesterase (PDE),cAMP,BC 11 38,Inhibitor,production,inhibit,levels,cells,BC11-38,BC 1138 686770-80-9