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BHPI
- CAS No.
- 56632-39-4
- Chemical Name:
- BHPI
- Synonyms
- BHPI;CS-2134;1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one;2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-
- CBNumber:
- CB33041388
- Molecular Formula:
- C21H17NO3
- Molecular Weight:
- 331.36
- MDL Number:
- MOL File:
- 56632-39-4.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| Melting point | 272-274 °C |
|---|---|
| Boiling point | 557.7±50.0 °C(Predicted) |
| Density | 1.320±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: 5 mg/ml; DMSO: 11 mg/ml; Ethanol: 14 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml |
| form | A crystalline solid |
| pka | 9.43±0.30(Predicted) |
| color | White to off-white |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
BHPI price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17750 | BHPI ≥95% | 56632-39-4 | 500μg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 17750 | BHPI ≥95% | 56632-39-4 | 1mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 17750 | BHPI ≥95% | 56632-39-4 | 5mg | $412 | 2024-03-01 | Buy |
| Tocris | 6116 | BHPI ≥98%(HPLC) | 56632-39-4 | 50 | $745 | 2021-12-16 | Buy |
| Tocris | 6116 | BHPI ≥98%(HPLC) | 56632-39-4 | 10 | $177 | 2021-12-16 | Buy |
BHPI Chemical Properties,Uses,Production
Description
BHPI is an antagonist of estrogen receptor α (ERα) that blocks 17β-estradiol-induced proliferation of drug-resistant breast, endometrial, and ovarian cancer cell lines at concentrations ranging from 10 to 1,000 nM. It is effective in vivo, driving tumor regression in mice bearing MCF-7 xenografts at a dose of 15 mg/kg daily. BHPI specifically inhibits ERα-dependent gene expression and protein synthesis by activating the unfolded protein response in cells.
Uses
BHPI is an antagonist of estrogen receptor α (ERα) that blocks 17β-estradiol-induced proliferation of drug-resistant breast, endometrial and ovarian cancer cell lines.
storage
Store at -20°C
BHPI Preparation Products And Raw materials
Raw materials
Preparation Products
BHPI Suppliers
Global( 55)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19881 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7552 | 61 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9805 | 58 |
| Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 | 505721671@qq.com | China | 3866 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 5960 | 55 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4660 | 60 |
BHPI
2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-
1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one
CS-2134
56632-39-4