BHPI

BHPI 구조식 이미지
카스 번호:
56632-39-4
상품명:
BHPI
동의어(영문):
BHPI;CS-2134;1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one;2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-
CBNumber:
CB33041388
분자식:
C21H17NO3
포뮬러 무게:
331.36
MOL 파일:
56632-39-4.mol

BHPI 속성

녹는점
272-274 °C
끓는 점
557.7±50.0 °C(Predicted)
밀도
1.320±0.06 g/cm3(Predicted)
용해도
DMF: 5 mg/ml; DMSO: 11 mg/ml; Ethanol: 14 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
물리적 상태
결정성 고체
산도 계수 (pKa)
9.43±0.30(Predicted)
색상
White to off-white

안전

BHPI C화학적 특성, 용도, 생산

개요

BHPI is an antagonist of estrogen receptor α (ERα) that blocks 17β-estradiol-induced proliferation of drug-resistant breast, endometrial, and ovarian cancer cell lines at concentrations ranging from 10 to 1,000 nM. It is effective in vivo, driving tumor regression in mice bearing MCF-7 xenografts at a dose of 15 mg/kg daily. BHPI specifically inhibits ERα-dependent gene expression and protein synthesis by activating the unfolded protein response in cells.

BHPI 준비 용품 및 원자재

원자재

준비 용품


BHPI 공급 업체

글로벌( 49)공급 업체
공급자 전화 이메일 국가 제품 수 이점
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131980 58
Haoyuan Chemexpress Co., Ltd. 021-58950125
info@chemexpress.com China 7553 61
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9707 58
Guangzhou QiYun Biotechnology Co., Ltd. 020-61288194 61288195
505721671@qq.com China 3868 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
klq@cw-bio.com China 3769 55
Musechem +1-800-259-7612
info@musechem.com United States 4662 60
Aikon International Limited 025-58859352 18068836627
sales01@aikonchem.com China 15085 58
DC Chemicals 021-58447131 13564518121
sales@dcchemicals.com China 9412 58

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