N-EPSILON-ACETYL-L-LYSINE
- CAS No.
- 692-04-6
- Chemical Name:
- N-EPSILON-ACETYL-L-LYSINE
- Synonyms
- H-LYS(AC)-OH;N-epsilon-acetyllysine;lys(ac);N6-Acetyllysine;N-EPSILON-ACETYL-L-LYS;NSC 102777;LYSINE(AC)-OH;H-L-LYS(AC)-OH;Nε-Ac-L-Lys-OH;Nε-Acetyllysine
- CBNumber:
- CB3308387
- Molecular Formula:
- C8H16N2O3
- Molecular Weight:
- 188.22
- MDL Number:
- MFCD00002639
- MOL File:
- 692-04-6.mol
Melting point | 250 °C (dec.)(lit.) |
---|---|
Boiling point | 323.23°C (rough estimate) |
Density | 1.1793 (rough estimate) |
refractive index | 1.4500 (estimate) |
storage temp. | -20°C |
solubility | Aqueous Base (Slightly), Water (Slightly) |
form | Powder |
pka | 2.53±0.24(Predicted) |
color | White |
Water Solubility | Soluble in water (miscible), and 80% acetic acid (50 mg/ml). |
Sensitive | Hygroscopic |
InChIKey | DTERQYGMUDWYAZ-ZETCQYMHSA-N |
CAS DataBase Reference | 692-04-6(CAS DataBase Reference) |
FDA UNII | 470AD5VY1X |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P280-P261 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 24/25-36-26 |
WGK Germany | 3 |
HS Code | 29241900 |
N-EPSILON-ACETYL-L-LYSINE price More Price(27)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | A4021 | Nω-Acetyl-L-lysine | 692-04-6 | 1g | $111 | 2024-03-01 | Buy |
Sigma-Aldrich | A4021 | Nω-Acetyl-L-lysine | 692-04-6 | 5g | $335 | 2024-03-01 | Buy |
TCI Chemical | A2652 | Nε-Acetyl-L-lysine >98.0%(T) | 692-04-6 | 1g | $51 | 2024-03-01 | Buy |
Alfa Aesar | J64139 | N(epsilon)-Acetyl-L-lysine, 99% | 692-04-6 | 1g | $56.65 | 2024-03-01 | Buy |
Alfa Aesar | J64139 | N(epsilon)-Acetyl-L-lysine, 99% | 692-04-6 | 5g | $195 | 2024-03-01 | Buy |
N-EPSILON-ACETYL-L-LYSINE Chemical Properties,Uses,Production
Description
Acetyllysine (or acetylated lysine) is an acetyl-derivative of the amino acid lysine. There are multiple forms of acetyllysine - this article refers to N-ε-acetyl-L-lysine. The other form is N-α-acetyl-Llysine.
In proteins, the acetylation of lysine residues is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Non-histone proteins are acetylated as well. Unlike the functionally similar methyllysine, acetyllysine does not carry a positive charge on its side chain.
Histone acetyltransferases (HATs) catalyze the addition of acetyl groups from acetyl-CoA onto certain lysine residues of histones and non-histone proteins. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from acetylated lysines.
Acetyllysine can be synthesized from lysine by the selective acetylation of the terminal amine group.
Chemical Properties
white crystalline powder
Uses
N-Epsilon-acetyl-l-lysine is used in the metabolomics study on the combined effect of cocaine and ethanol via liquid chromatography-mass spectrometry metabolomics approach.
Definition
ChEBI: An N6-acyl-L-lysine where the N6-acyl group is specified as acetyl.
Biochem/physiol Actions
Nε-Acetyl-L-lysine (L-AcK) is an R-chain N-acetylated α amino acid used together with other lysine analogues to differentiate and characterized various aminoacylases and regulator 2 (Sir2) enzymes/sirtuins.
N-EPSILON-ACETYL-L-LYSINE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16911 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
GenicBio Limited | +86-21-37621270 | service@genicbio.com | CHINA | 991 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29892 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 | CHINA | 3904 | 58 | |
GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
View Lastest Price from N-EPSILON-ACETYL-L-LYSINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
![]() |
2019-07-06 | N-EPSILON-ACETYL-L-LYSINE
692-04-6
|
US $1.00 / KG | 1KG | 99% | 20kg | Career Henan Chemical Co |
-
- N-EPSILON-ACETYL-L-LYSINE
692-04-6
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
692-04-6(N-EPSILON-ACETYL-L-LYSINE)Related Search:
1of4