ChemicalBook >> CAS DataBase List >>TGR-1202 (R-enantiomer)
TGR-1202 (R-enantiomer)
- CAS No.
- 1532533-69-9
- Chemical Name:
- TGR-1202 (R-enantiomer)
- Synonyms
- RP5264 R-enantiomer;TGR-1202 (R-enantiomer);Umbralisib (TGR-1202) R-enantiomer;TGR-1202 R-enantiomer|||RP5264 R-enantiomer;2-[(1R)-1-{4-amino-3-[3-fluoro-4-(propan-2-yloxy)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}ethyl]-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one;4H-1-Benzopyran-4-one, 2-[(1R)-1-[4-amino-3-[3-fluoro-4-(1-methylethoxy)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-6-fluoro-3-(3-fluorophenyl)-
- CBNumber:
- CB33160078
- Molecular Formula:
- C31H24F3N5O3
- Molecular Weight:
- 571.55
- MDL Number:
- MOL File:
- 1532533-69-9.mol
Last updated:2024-07-02 08:55:06
TGR-1202 (R-enantiomer) Chemical Properties,Uses,Production
Description
Umbralisib R-enantiomer (TGR-1202 R-enantiomer) is a PI3Kδ inhibitor, which is the less active enantiomer of TGR-1202. PI3Kδ
Umbralisib R-enantiomer (TGR-1202 R-enantiomer) (Formula A) exhibits a 50% inhibitory concentration (IC50) with respect to the δ type PI3-kinase that is at least 20-fold lower than the inhibitor's IC50 with respect to the rest of the other PI3K isoforms (i.e., a, β, and γ)[1].
References
[1]. Michael Weiss, et al. Combination of anti-cd20 antibody and pi3 kinase selective inhibitor. WO2014071125A1.
TGR-1202 (R-enantiomer) Preparation Products And Raw materials
TGR-1202 (R-enantiomer) Suppliers
Global( 13)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +8618168183658 | sales1@artkmedchem.com | China | 39009 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4662 | 60 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Zeye Biotechnology Co., Ltd. | 021-61998551 13122364865 | sale1@shzysw.net | China | 9771 | 58 |
| Absin Bioscience Inc. | 021-38015121 15000105423 | chenjw@absin.cn | China | 24734 | 58 |
| Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd. | 15720605021 | zhang_lei@jsnchem.com | China | 1546 | 58 |
| PharmaBlock Sciences (Nanjing), Inc. | 4000255188 | sun_dan@PharmaBlock.com | China | 7268 | 58 |
TGR-1202 (R-enantiomer)
Umbralisib (TGR-1202) R-enantiomer
RP5264 R-enantiomer
4H-1-Benzopyran-4-one, 2-[(1R)-1-[4-amino-3-[3-fluoro-4-(1-methylethoxy)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-6-fluoro-3-(3-fluorophenyl)-
2-[(1R)-1-{4-amino-3-[3-fluoro-4-(propan-2-yloxy)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}ethyl]-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one
TGR-1202 R-enantiomer|||RP5264 R-enantiomer
1532533-69-9
C31H24F3N5O3