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Propargyl-PEG12-amine

CAS No.
2264091-73-6
Chemical Name:
Propargyl-PEG12-amine
Synonyms
Propyne-PEG12-NH2;Propargyl-PEG12-amine;Propargyl-PEG13- Amine;3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxanonatriacont-38-yn-1-amine
CBNumber:
CB33373757
Molecular Formula:
C27H53NO12
Molecular Weight:
583.71
MDL Number:
MOL File:
2264091-73-6.mol
Last updated:2024-03-26 17:16:27

Propargyl-PEG12-amine Properties

Boiling point 608.1±50.0 °C(Predicted)
Density 1.084±0.06 g/cm3(Predicted)
pka 8.74±0.10(Predicted)

Propargyl-PEG12-amine Chemical Properties,Uses,Production

Biological Activity

Propargyl-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Propargyl-PEG12-amine Preparation Products And Raw materials

Raw materials

Preparation Products

Propargyl-PEG12-amine Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Alpha Biopharmaceuticals Co., Ltd
+86-15542445688 sales@alabiochem.com China 888 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Alabiochem Tech.Co., Ltd. 0512-58900862 400-0707518 sales@alabiochem.com China 997 59
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4824 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
Affinity(Wuhan)Ltd. 15841022315 sales@affinitytech.cn China 2485 58
Zhengzhou Converging Chemical Co. LTD 0371-0371-53399770 18037166334 2853031800@qq.com China 2957 58
shanghai yayu biomedical co.,ltd 021-54370211 18051886391 3007215920@qq.com China 2991 58
Shochem (Shanghai) Co.,Ltd 13611745246 13816874662 sales@shochem.com China 540 58

View Lastest Price from Propargyl-PEG12-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Propargyl-PEG12-amine pictures 2024-03-26 Propargyl-PEG12-amine
2264091-73-6
US $0.00 / g 1g >95.00% 1g Xian confluore Biological Technology Co., Ltd.
Propargyl-PEG12-amine Propyne-PEG12-NH2 Propargyl-PEG13- Amine 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxanonatriacont-38-yn-1-amine 2264091-73-6