2-Diethylaminoethylchloride hydrochloride
- CAS No.
- 869-24-9
- Chemical Name:
- 2-Diethylaminoethylchloride hydrochloride
- Synonyms
- DEC;2-Chlorotriethylamine hydrochloride;DEAC HCL;CCMO-39-002;oro-N,N-diethyL;CED 50% Solution;DEAC 65% Solution;(2-Chloroethyl)di;TRISMETHOXYBENZENE;3,5-DIMETHOXYANISOLE
- CBNumber:
- CB3371006
- Molecular Formula:
- C6H15Cl2N
- Molecular Weight:
- 172.1
- MDL Number:
- MFCD00012519
- MOL File:
- 869-24-9.mol
- MSDS File:
- SDS
Melting point | 50-53 °C(lit.) |
---|---|
Boiling point | 255 °C(lit.) |
Density | 1.1919 (rough estimate) |
vapor pressure | 0Pa at 25℃ |
refractive index | 1.6000 (estimate) |
Flash point | 186 °F |
storage temp. | Poison room |
solubility | methanol: 0.1 g/mL, clear, colorless |
form | Crystalline Powder |
color | White to slightly beige |
PH | 5 (100g/l, H2O, 20℃) |
Water Solubility | 2000 g/L (20 ºC) |
Sensitive | Moisture Sensitive |
BRN | 3591991 |
Stability | Hygroscopic, Moisture Sensitive |
InChIKey | RAGSWDIQBBZLLL-UHFFFAOYSA-N |
CAS DataBase Reference | 869-24-9(CAS DataBase Reference) |
Indirect Additives used in Food Contact Substances | BETA-DIETHYLAMINOETHYL CHLORIDE |
FDA UNII | YCY6EQT3WA |
EPA Substance Registry System | Diethyl-(2-chloroethyl)amine hydrochloride (869-24-9) |
UNSPSC Code | 12352100 |
NACRES | NA.22 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() ![]() GHS05,GHS06,GHS08 |
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Signal word | Danger | |||||||||
Hazard statements | H300-H314-H341-H412 | |||||||||
Precautionary statements | P201-P260-P280-P301+P310+P330-P303+P361+P353-P305+P351+P338 | |||||||||
Hazard Codes | Xn,T,Xi,T+ | |||||||||
Risk Statements | 22-36/37/38-26-24/25-23/24/25 | |||||||||
Safety Statements | 26-36-45-36/37/39-28A | |||||||||
RIDADR | UN 2811 6.1/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | DC2810000 | |||||||||
Hazard Note | Irritant/Very Toxic | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | II | |||||||||
HS Code | 29211980 | |||||||||
Hazardous Substances Data | 869-24-9(Hazardous Substances Data) | |||||||||
NFPA 704 |
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2-Diethylaminoethylchloride hydrochloride Chemical Properties,Uses,Production
Chemical Properties
2-Diethylaminoethylchloride hydrochloride is colourless to beige crystals
Uses
2-Chloro-N,N-diethylethylamine hydrochloride (65% in water) (DEC 65) is used as intermediate for the syntheses of pharmaceuticals (e.g. amiodarone, butetamate citrate, flurazepam and naftidrofuryl). Product Data Sheet
Uses
2-Chloro-N,N-diethylethylamine hydrochloride can be used as an alkylating reagent for the synthesis of:
- Substituted oxindole derivatives to be used as growth hormone secretagogs.
- 1-Substituted-5,6-dinitrobenzimidazoles with antimicrobial and antiprotozoal activities.
- Thiophene containing triarylmethane (TRAM) derivatives to be used as antitubercular agents.
- Tris(2-(diethylamino)ethyl)amine to be used as a catalyst in combination with CuBr (Et6TREN/CuBr) for atom transfer radical polymerization of n-butyl acrylate.
It can also be used for the derivatization of chitosan to incorporate aminofunctionality onto it at C-6 position.
Uses
2-Diethylaminoethylchloride hydrochloride is used as intermediate for the syntheses of pharmaceuticals (e.g. amiodarone, butetamate citrate, flurazepam and naftidrofuryl). Product Data Sheet
Purification Methods
Crystallise the salt from absolute MeOH (to remove highly coloured impurities). [Beilstein 4 III 240.]
2-Diethylaminoethylchloride hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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