ChemicalBook >> CAS DataBase List >>5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE

5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE

5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE structure

CAS No.: 158848-32-9

Chemical Name:: 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE

Synonyms: GR 159897;5-Fluoro-3-[2-[4-methoxy-4-[[-phenylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indole;(R)-5-Fluoro-3-[2-[4-methoxy-4-[(phenylsulfinyl)methyl]-1-piperidinyl]ethyl]-1H-indole;5-Fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]-1-piperidinyl]ethyl]-1H-indole;5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE;1H-Indole, 5-fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]-1-piperidinyl]ethyl]-

CBNumber:: CB3376531

Molecular Formula:: C23H27FN2O2S

Molecular Weight:: 414.54

MDL Number:: MFCD05665140

MOL File:: 158848-32-9.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Properties

Boiling point	600.2±55.0 °C(Predicted)
Density	1.29±0.1 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMSO: ~24 mg/mL, soluble
pka	16.46±0.30(Predicted)
form	solid
color	off-white

SAFETY

Risk and Safety Statements

WGK Germany	3

5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	1274	GR159897 ≥97%(HPLC)	158848-32-9	10	$224	2021-12-16	Buy
Tocris	1274	GR159897 ≥97%(HPLC)	158848-32-9	50	$915	2021-12-16	Buy
TRC	G779510	GR159897	158848-32-9	25mg	$950	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000295	5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE 95.00%	158848-32-9	50MG	$1327.97	2021-12-16	Buy
Biosynth Carbosynth	FF101805	GR 159897	158848-32-9	5mg	$250	2021-12-16	Buy

Product number	Packaging	Price	Buy
1274	10	$224	Buy
1274	50	$915	Buy
G779510	25mg	$950	Buy
KIN0000295	50MG	$1327.97	Buy
FF101805	5mg	$250	Buy

5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Chemical Properties,Uses,Production

Uses

GR 159897 is an NK2 receptor antagonist which aids in the treatment of IBS.

Biological Activity

A potent, selective, non-peptide, orally active neurokinin NK 2 receptor antagonist. Competes for binding of [ 3 H]GR100679 to hNK 2 -transfected CHO cells with a pK i of 9.5. Inhibits NK 2 receptor-mediated contraction of guinea pig trachea with a pA 2 of 8.7. Anxiolytic in vivo .

storage

Desiccate at -20°C

5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Suppliers

Global( 28)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	0571-85361029	synstar518@163.com	China	1990	58
BOC Sciences	--	info@bocsci.com	USA	0	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44918	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8617	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223;	psaitong@jm-bio.com	China	29774	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
EMMX Biotechnology LLC	60
Shanghai EFE Biological Technology Co., Ltd.	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	58
BOC Sciences	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Energy Chemical	58
Changzhou Furuisi Biotechnology Co., Ltd	58
Beijing Jin Ming Biotechnology Co., Ltd.	58

158848-32-9(5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE)Related Search:

5-FLUORO-N,N-DIMETHYLTRYPTAMINE 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE

5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE 5-Fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]-1-piperidinyl]ethyl]-1H-indole 5-Fluoro-3-[2-[4-methoxy-4-[[-phenylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indole GR 159897 (R)-5-Fluoro-3-[2-[4-methoxy-4-[(phenylsulfinyl)methyl]-1-piperidinyl]ethyl]-1H-indole 1H-Indole, 5-fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]-1-piperidinyl]ethyl]- 158848-32-9 C23H27O2N2SF C23H27FN2O2S