Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:GR 159897;5-Fluoro-3-[2-[4-Methoxy-4-[[(R)-phenylsulphinyl]Methyl]-1-piperidinyl]ethyl]-1H-indole CAS:158848-32-9 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
EMMX Biotechnology LLC
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Tel: |
888-539-0666 |
Email: |
info@emmx.com |
Products Intro: |
Product Name:GR 159897 CAS:158848-32-9 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Basic information |
Product Name: | 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE | Synonyms: | 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE;5-Fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]-1-piperidinyl]ethyl]-1H-indole;5-Fluoro-3-[2-[4-methoxy-4-[[-phenylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indole;GR 159897;(R)-5-Fluoro-3-[2-[4-methoxy-4-[(phenylsulfinyl)methyl]-1-piperidinyl]ethyl]-1H-indole;1H-Indole, 5-fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]-1-piperidinyl]ethyl]- | CAS: | 158848-32-9 | MF: | C23H27FN2O2S | MW: | 414.54 | EINECS: | | Product Categories: | | Mol File: | 158848-32-9.mol | ![5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Structure](CAS/GIF/158848-32-9.gif) |
| 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Chemical Properties |
Boiling point | 600.2±55.0 °C(Predicted) | density | 1.29±0.1 g/cm3(Predicted) | storage temp. | −20°C | solubility | DMSO: ~24 mg/mL, soluble | pka | 16.46±0.30(Predicted) | form | solid | color | off-white |
| 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Usage And Synthesis |
Uses | GR 159897 is an NK2 receptor antagonist which aids in the treatment of IBS. | Biological Activity | A potent, selective, non-peptide, orally active neurokinin NK 2 receptor antagonist. Competes for binding of [ 3 H]GR100679 to hNK 2 -transfected CHO cells with a pK i of 9.5. Inhibits NK 2 receptor-mediated contraction of guinea pig trachea with a pA 2 of 8.7. Anxiolytic in vivo . | storage | Desiccate at -20°C |
| 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Preparation Products And Raw materials |
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