5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
- CAS No.
- 124750-53-4
- Chemical Name:
- 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
- Synonyms
- TTMB;ENTERPRISESTANDARD;Losartan Impurity 9;Olmesartan TTMB impurity;5-[2-(4-methylphenyl)phenyl]-1-trityltetrazole;5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole;5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole;Olmesartan Medoxomil Impurity 24(Losartan Impurity 9);N-(TRIPHENYLMETHYL)-5-(4'-METHYLBIPHENYL-2-YL)TETRAZOLE;n-(triphenylmethyl)-5-(4'-methylbiphenyl-2-yl-)terazole
- CBNumber:
- CB3438158
- Molecular Formula:
- C33H26N4
- Molecular Weight:
- 478.59
- MDL Number:
- MFCD00665220
- MOL File:
- 124750-53-4.mol
- MSDS File:
- SDS
Melting point | 166-169 °C(Solv: ethyl acetate (141-78-6); dichloromethane (75-09-2)) |
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Boiling point | 681.6±65.0 °C(Predicted) |
Density | 1.13±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform (Slightly) |
form | Solid |
pka | 0.30±0.10(Predicted) |
color | Off-White |
CAS DataBase Reference | 124750-53-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Danger |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c |
5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | T889172 | N-Triphenylmethyl-5-[4''-methylbiphenyl-2-yl]tetrazole-d4 | 124750-53-4 | 10mg | $165 | 2021-12-16 | Buy |
Matrix Scientific | 093682 | 5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 95+% | 124750-53-4 | 250mg | $341 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | D62492 | N-Triphenylmethyl-5-[4??-methylbiphenyl-2-yl]tetrazole-d4 | 124750-53-4 | 10mg | $650 | 2021-12-16 | Buy |
Matrix Scientific | 093682 | 5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 95+% | 124750-53-4 | 1g | $756 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | APN0000403 | 5-(4'-METHYLBIPHENYL-2-YL)-1-TRITYL-1H-TETRAZOLE 95.00% | 124750-53-4 | 1G | $780.15 | 2021-12-16 | Buy |
5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Chemical Properties,Uses,Production
Chemical Properties
Off-white Solid
Uses
An intermediate in the preparation of labelled Candesartan.
Uses
5-?(4''-?Methyl-?[1,?1''-?biphenyl]?-?2-?yl)?-?1-?trityl-?1H-?tetrazole is a reactant in the synthesis of anti-microbial agents.
Synthesis
5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole is prepared by the reaction of trityl chloride and 2-(tetrazol-5-yl)-4'-methyl-1,1'-biphenyl. The specific synthesis steps are as follows:
Dissolve compound 2 (200 g) with stirring at 40°C 700mL of acetone, Aqueous sodium hydroxide solution (40.67 g sodium hydroxide dissolved in 160 mL water) is added, Continue stirring for 1h, A solution of triphenylchloromethane in acetone (270.8 g of triphenylmethyl chloride dissolved in 800 mL of acetone) was initially added dropwise. The solid was added dropwise and gradually evolved into a white turbid liquid. The reaction was monitored by TLC until it was completely filtered off and washed with water to give a solid as intermediate 3. The solid was blow dried at 50°C to give white intermediate 3 (385 g), yield: 95.2%, HPLC: 99.44%.
5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13214 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-08-22 | Olmesartan Medoxomil Impurity 19
124750-53-4
|
US $0.00-0.00 / mg | 10mg | 98% | 500mg | ShenZhen H&D Pharmaceutical Technology Co., LTD | |
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2022-09-21 | 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
124750-53-4
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
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2020-05-10 | 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
124750-53-4
|
US $0.00-0.00 / Kg | 1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
-
- Olmesartan Medoxomil Impurity 19
124750-53-4
- US $0.00-0.00 / mg
- 98%
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
- 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
124750-53-4
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
124750-53-4
- US $0.00-0.00 / Kg
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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