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CAY10726

CAY10726 Structure
CAY10726 structure
CAS No.
1611446-66-2
Chemical Name:
CAY10726
Synonyms
CAY10726;16-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-hexadecanoicacid;Hexadecanoic acid, 16-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-
CBNumber:
CB34666984
Molecular Formula:
C24H36ClF3N2O3
Molecular Weight:
493
MDL Number:
MOL File:
1611446-66-2.mol
Last updated:2023-07-14 17:34:42
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CAY10726 Properties

Boiling point 560.9±50.0 °C(Predicted)
Density 1.176±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 5 mg/ml; Ethanol: 12 mg/ml
form A crystalline solid
pka 4.78±0.10(Predicted)

CAY10726 price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23859 CAY10726 ≥98% 1611446-66-2 1mg $32 2024-03-01 Buy
Cayman Chemical 23859 CAY10726 ≥98% 1611446-66-2 5mg $139 2024-03-01 Buy
Cayman Chemical 23859 CAY10726 ≥98% 1611446-66-2 10mg $243 2024-03-01 Buy
Cayman Chemical 23859 CAY10726 ≥98% 1611446-66-2 25mg $533 2024-03-01 Buy
AK Scientific 8471DW 16-[[4-Chloro-3-(trifluoromethyl)phenyl]carbamoylamino]hexadecanoicacid 1611446-66-2 5mg $252 2021-12-16 Buy
Product number Packaging Price Buy
23859 1mg $32 Buy
23859 5mg $139 Buy
23859 10mg $243 Buy
23859 25mg $533 Buy
8471DW 5mg $252 Buy

CAY10726 Chemical Properties,Uses,Production

Description

CAY10726 is an arylurea fatty acid.1 It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 μM. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane. In vivo, CAY10726 (2.5-40 mg/kg) reduces tumor volume and increases tumor cell apoptosis in a mouse MDA-MB-231 breast cancer xenograft model in a dose-dependent manner.

References

1. Rawling, T., Choucair, H., Koolaji, N., et al. A novel arylurea fatty acid that targets the mitochondrion and depletes cardiolipin to promote killing of breast cancer cells J. Med. Chem. 60(20),8661-8666(2017).

CAY10726 Preparation Products And Raw materials

Raw materials

Preparation Products

CAY10726 Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7979 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8736 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28070 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
CAY10726 Hexadecanoic acid, 16-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]- 16-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-hexadecanoicacid 1611446-66-2 C24H36ClF3N2O3