1,4-Dioxaspiro[4.5]decan-8-one
- CAS No.
- 4746-97-8
- Chemical Name:
- 1,4-Dioxaspiro[4.5]decan-8-one
- Synonyms
- 1,4-CYCLOHEXANEDIONE MONOETHYLENE ACETAL;1,4-CYCLOHEXANEDIONE MONOETHYLENE KETAL;1,4-Cyclohexanedione ethylene ketal;cyclohexanedione monoethylene ketal;KEHK;4-Cyclohexanedione Mo;cyclohexanedione monoacetal;4-Dioxaspiro[4.5]decan-8-one;1,4-Dioxiro[4.5]decan-8-one.;1,4-Cyclohexanedion Monoethyl
- CBNumber:
- CB3496677
- Molecular Formula:
- C8H12O3
- Molecular Weight:
- 156.18
- MDL Number:
- MFCD00010214
- MOL File:
- 4746-97-8.mol
- MSDS File:
- SDS
Melting point | 70-73 °C (lit.) |
---|---|
Boiling point | 112C |
Density | 1.0887 (rough estimate) |
refractive index | 1.4430 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | Soluble in chloroform & methanol. |
form | Crystalline Powder or Crystals |
color | White to beige |
Sensitive | Moisture Sensitive |
BRN | 117631 |
InChI | InChI=1S/C8H12O3/c9-7-1-3-8(4-2-7)10-5-6-11-8/h1-6H2 |
InChIKey | VKRKCBWIVLSRBJ-UHFFFAOYSA-N |
SMILES | O1C2(CCC(=O)CC2)OCC1 |
CAS DataBase Reference | 4746-97-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 22-24/25-36/37/39-26 | |||||||||
WGK Germany | 3 | |||||||||
F | 8-10-21 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29110000 | |||||||||
NFPA 704 |
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1,4-Dioxaspiro[4.5]decan-8-one price More Price(64)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 274879 | 1,4-Cyclohexanedione monoethylene acetal 97% | 4746-97-8 | 5g | $42 | 2024-03-01 | Buy |
Sigma-Aldrich | 274879 | 1,4-Cyclohexanedione monoethylene acetal 97% | 4746-97-8 | 25g | $77.6 | 2024-03-01 | Buy |
TCI Chemical | C1292 | 1,4-Cyclohexanedione Monoethyleneketal >98.0%(GC) | 4746-97-8 | 5g | $17 | 2024-03-01 | Buy |
TCI Chemical | C1292 | 1,4-Cyclohexanedione Monoethyleneketal >98.0%(GC) | 4746-97-8 | 25g | $42 | 2024-03-01 | Buy |
Alfa Aesar | A10408 | 1,4-Cyclohexanedione monoethylene acetal, 97% | 4746-97-8 | 5g | $40.65 | 2024-03-01 | Buy |
1,4-Dioxaspiro[4.5]decan-8-one Chemical Properties,Uses,Production
Chemical Properties
1,4-Dioxaspiro[4.5]decan-8-one is white to beige crystalline powder or crystals
Uses
1,4-Dioxaspiro[4.5]decan-8-one is used in the preparation of series of potent analgesic compounds. 1,4-Cyclohexanedione Monoethylene Acetal is also used as a building block in the synthesis of tritium labelled probes for the autoradiography study of the dopamine reuptake complex.
Uses
Intermediates of Liquid Crystals
Uses
1,4-Cyclohexanedione is used in the preparation of series of potent analgesic compounds. 1,4-Cyclohexanedione is also used as a building block in the synthesis of tritium labelled probes for the autoradiography study of the dopamine reuptake complex.
Application
1,4-Dioxaspiro[4.5]decan-8-one can be used:
(1) Used in a study of microwave-assisted reductive amination.
(2) Via a novel aromatization process, this bicyclic frame can be converted into a series of 5-alkoxytryptamine derivatives including serotonin, melatonin and bufotenin.
Purification Methods
Recrystallise it from pet ether. It sublimes slowly on attempted distillation. Also purify it by dissolving it in Et2O and adding pet ether (b 60-80o) until turbid and cooling. [Gardner et al. J Am Chem Soc 22 1206 1957, Britten & Lockwood J Chem Soc Perkin Trans 1 1824 1974.] [Beilstein 19/4 V 93.]
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![4746-97-8](/CAS/GIF/4746-97-8.gif)
1,4-Dioxaspiro[4.5]decan-8-one Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Xi'an Tuochao Biotechnology Co., Ltd | +86-02988764766 +86-18092957403 | chen.zeshan@xatuochao.com | China | 110 | 58 |
Nanjing Hengbei Chemicals Co., Ltd. | +86-25-58393656 | sales@hengbeichem.cn | China | 6856 | 58 |
Nanjing Yushan Wanfang Biotechnology Co., Ltd. | +86-025-84918180 +86-18014482516 | 3552541679@qq.com | China | 1001 | 58 |
Hebei Maison Chemical Co.,Ltd. | +8615511852758 | sales@maisonchem.com.cn | China | 484 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
QINGDAO HONG JIN CHEMCIAL CO.,LTD. | 532-83657313 | hjt@hong-jin.com | China | 228 | 58 |
View Lastest Price from 1,4-Dioxaspiro[4.5]decan-8-one manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-08-23 | 1,4-Cyclohexanedione monoethyleneacetal
4746-97-8
|
US $20.00 / KG | 1KG | 99% | 300 Tons/ year | Speranza Chemical Co., Ltd. | |
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2024-08-22 | 1,4-Dioxaspiro[4.5]decan-8-one
4746-97-8
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
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2024-08-20 | 1,4-Dioxaspiro[4.5]decan-8-one
4746-97-8
|
US $289.00 / KG | 1KG | 98% | 1-10MT | Baoji Guokang Bio-Technology Co., Ltd. |
-
- 1,4-Cyclohexanedione monoethyleneacetal
4746-97-8
- US $20.00 / KG
- 99%
- Speranza Chemical Co., Ltd.
-
- 1,4-Dioxaspiro[4.5]decan-8-one
4746-97-8
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 1,4-Dioxaspiro[4.5]decan-8-one
4746-97-8
- US $289.00 / KG
- 98%
- Baoji Guokang Bio-Technology Co., Ltd.