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ChemicalBook >> CAS DataBase List >>1,4-Dioxaspiro[4.5]decan-8-one

1,4-Dioxaspiro[4.5]decan-8-one

1,4-Dioxaspiro[4.5]decan-8-one Structure
1,4-Dioxaspiro[4.5]decan-8-one structure
CAS No.
4746-97-8
Chemical Name:
1,4-Dioxaspiro[4.5]decan-8-one
Synonyms
1,4-CYCLOHEXANEDIONE MONOETHYLENE ACETAL;1,4-CYCLOHEXANEDIONE MONOETHYLENE KETAL;1,4-Cyclohexanedione ethylene ketal;cyclohexanedione monoethylene ketal;KEHK;4-Cyclohexanedione Mo;cyclohexanedione monoacetal;4-Dioxaspiro[4.5]decan-8-one;1,4-Dioxiro[4.5]decan-8-one.;1,4-Cyclohexanedion Monoethyl
CBNumber:
CB3496677
Molecular Formula:
C8H12O3
Molecular Weight:
156.18
MDL Number:
MFCD00010214
MOL File:
4746-97-8.mol
MSDS File:
SDS
Last updated:2024-04-22 19:50:33
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1,4-Dioxaspiro[4.5]decan-8-one Properties

Melting point 70-73 °C (lit.)
Boiling point 112C
Density 1.0887 (rough estimate)
refractive index 1.4430 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in chloroform & methanol.
form Crystalline Powder or Crystals
color White to beige
Sensitive Moisture Sensitive
BRN 117631
InChI InChI=1S/C8H12O3/c9-7-1-3-8(4-2-7)10-5-6-11-8/h1-6H2
InChIKey VKRKCBWIVLSRBJ-UHFFFAOYSA-N
SMILES O1C2(CCC(=O)CC2)OCC1
CAS DataBase Reference 4746-97-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36/37/39-26
WGK Germany  3
F  8-10-21
Hazard Note  Irritant
HS Code  29110000
NFPA 704
1
2 0

1,4-Dioxaspiro[4.5]decan-8-one price More Price(64)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 274879 1,4-Cyclohexanedione monoethylene acetal 97% 4746-97-8 5g $42 2024-03-01 Buy
Sigma-Aldrich 274879 1,4-Cyclohexanedione monoethylene acetal 97% 4746-97-8 25g $77.6 2024-03-01 Buy
TCI Chemical C1292 1,4-Cyclohexanedione Monoethyleneketal >98.0%(GC) 4746-97-8 5g $17 2024-03-01 Buy
TCI Chemical C1292 1,4-Cyclohexanedione Monoethyleneketal >98.0%(GC) 4746-97-8 25g $42 2024-03-01 Buy
Alfa Aesar A10408 1,4-Cyclohexanedione monoethylene acetal, 97% 4746-97-8 5g $40.65 2024-03-01 Buy
Product number Packaging Price Buy
274879 5g $42 Buy
274879 25g $77.6 Buy
C1292 5g $17 Buy
C1292 25g $42 Buy
A10408 5g $40.65 Buy

1,4-Dioxaspiro[4.5]decan-8-one Chemical Properties,Uses,Production

Chemical Properties

1,4-Dioxaspiro[4.5]decan-8-one is white to beige crystalline powder or crystals

Uses

1,4-Dioxaspiro[4.5]decan-8-one is used in the preparation of series of potent analgesic compounds. 1,4-Cyclohexanedione Monoethylene Acetal is also used as a building block in the synthesis of tritium labelled probes for the autoradiography study of the dopamine reuptake complex.

Uses

Intermediates of Liquid Crystals

Uses

1,4-Cyclohexanedione is used in the preparation of series of potent analgesic compounds. 1,4-Cyclohexanedione is also used as a building block in the synthesis of tritium labelled probes for the autoradiography study of the dopamine reuptake complex.

Application

1,4-Dioxaspiro[4.5]decan-8-one can be used:
(1) Used in a study of microwave-assisted reductive amination.
(2) Via a novel aromatization process, this bicyclic frame can be converted into a series of 5-alkoxytryptamine derivatives including serotonin, melatonin and bufotenin.

Purification Methods

Recrystallise it from pet ether. It sublimes slowly on attempted distillation. Also purify it by dissolving it in Et2O and adding pet ether (b 60-80o) until turbid and cooling. [Gardner et al. J Am Chem Soc 22 1206 1957, Britten & Lockwood J Chem Soc Perkin Trans 1 1824 1974.] [Beilstein 19/4 V 93.]

1,4-Dioxaspiro[4.5]decan-8-one synthesis

6289-46-9
107-21-1
4746-97-8
Synthesis of 1,4-Dioxaspiro[4.5]decan-8-one from 2,5-dioxo-1,4-cyclohexanedicarboxylic acid dimethyl ester and Ethylene glycol

1,4-Dioxaspiro[4.5]decan-8-one Preparation Products And Raw materials

Raw materials

Preparation Products

4,4-DIFLUOROCYCLOHEXANONE methyl 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate 4-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3-CYCLOHEXEN-1-YL]-MORPHOLINE Pramipexole impurity 7 4-(TERT-BUTYLDIMETHYLSILYLOXY)CYCLOHEXA&
4-Methoxycyclohexanol 4-(Benzyloxy)cyclohexanone 4-Pentylcyclohexanone INCB8761(PF-4136309) 4-Propylcyclohexanone
4-CYANOCYCLOHEXANONE CYCLIC ETHYLENE ACETAL 4-Methoxycyclohexanon

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1,4-Dioxaspiro[4.5]decan-8-one Suppliers

Global( 583)Suppliers
Supplier Tel Email Country ProdList Advantage
Xi'an Tuochao Biotechnology Co., Ltd 		+86-02988764766 +86-18092957403 chen.zeshan@xatuochao.com China 110 58
Nanjing Hengbei Chemicals Co., Ltd.
+86-25-58393656 sales@hengbeichem.cn China 6854 58
Nanjing Yushan Wanfang Biotechnology Co., Ltd.
+86-025-84918180 +86-18014482516 3552541679@qq.com China 997 58
Hebei Maison Chemical Co.,Ltd.
+8615511852758 sales@maisonchem.com.cn China 484 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 18779 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29884 58
QINGDAO HONG JIN CHEMCIAL CO.,LTD. 		532-83657313 hjt@hong-jin.com China 228 58
Supplier Advantage
Xi'an Tuochao Biotechnology Co., Ltd 		58
Nanjing Hengbei Chemicals Co., Ltd.
58
Nanjing Yushan Wanfang Biotechnology Co., Ltd.
58
Hebei Maison Chemical Co.,Ltd.
58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
career henan chemical co 		58
QINGDAO HONG JIN CHEMCIAL CO.,LTD. 		58

View Lastest Price from 1,4-Dioxaspiro[4.5]decan-8-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,4-Dioxaspiro[4.5]decan-8-one pictures 2024-11-22 1,4-Dioxaspiro[4.5]decan-8-one
4746-97-8
 US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
1,4-Cyclohexanedione monoethyleneacetal pictures 2024-11-22 1,4-Cyclohexanedione monoethyleneacetal
4746-97-8
 US $20.00 / KG 1KG 99% 300 Tons/ year Speranza Chemical Co., Ltd.
1,4-Dioxaspiro[4.5]decan-8-one pictures 2024-11-18 1,4-Dioxaspiro[4.5]decan-8-one
4746-97-8
 US $0.00 / KG 1KG 99.5% 1T Xi'an Tuochao Biotechnology Co., Ltd

1,4-Dioxaspiro[4.5]decan-8-one Spectrum

1,4-Dioxaspiro[4.5]decan-8-one(4746-97-8)MS1,4-Dioxaspiro[4.5]decan-8-one(4746-97-8)1HNMR1,4-Dioxaspiro[4.5]decan-8-one(4746-97-8)13CNMR1,4-Dioxaspiro[4.5]decan-8-one(4746-97-8)IR11,4-Dioxaspiro[4.5]decan-8-one(4746-97-8)IR21,4-Dioxaspiro[4.5]decan-8-one(4746-97-8)Raman

4746-97-8(1,4-Dioxaspiro[4.5]decan-8-one)Related Search:

Diethylene glycol DIOXOPROMETHAZINE HCL 2-Bromomethyl-1,3-dioxolane Decane Cyclohexanone
1,4-Cyclohexanedione Buspirone Selenium dioxide 1,4-Dioxane 2,2-DIMETHYL-1,3-DIOXOLANE
4-HYDROXYCYCLOHEXANONE 1,1-DIMETHOXYCYCLOHEXANE 2-METHYL-1,3-DIOXOLANE DIOXOPROMETHAZINE HEXANAL DIMETHYL ACETAL
1,3-Dioxolane 2-ETHYL-2-METHYL-1,3-DIOXOLANE 3,3-DIMETHOXYHEXANE

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Substituted 1,2,4,9-tetrahydrospiro[carbazole-3,2'-[1,3]dioxane] 1,4-Cyclohexanedione monoethlylene acetal 1,4-Cyclohexanedione monoethylene ketal for synthesis 4-Dioxaspiro[4.5]decan-8-one Cyclohexane-1,4-dione monoethylene ketal 1,4-Cyclohexanedion monoethylene acetal 1,4-Dioxiro[4.5]decan-8-one. 1,4-CYCLOHEXANEDIONE MONOETHYLENE ACETAL (1,4-DIOXASPIRO(4.5)DECAN-8-ONE) 1,4-Dioxaspiro[4.5]decan-8-one, Cyclohexane-1,4-dione monoethylene ketal Cyclohexane-1,4-dione monoethylene acetal KEHK 1,4-Dioxaspiro[4.5]decan-8-one ,99% 1,4-DIOXASPIRO[4.5]DECAN-8-ONE 1,4-DIOXASPIRO[4.5]-8-DECANONE CYCLOHEXANEDIONE(1,4-) MONOETHYLENE 4-Cyclohexanedione Monoethylene acetal 1,4-Dioxaspiro[4.5]decan-8-one 99% Cyclohexane-1,4-dione monoethylene ketal, Cyclohexane-1,4-dione monoethylene acetal 1,4-Cyclohexanedion Monoethyl 1,4-Dioxaspiro[4.5]decan-8-one, 98% 25GR Cyclohexane-1,4-dione monoethylene ketal, 8-Oxo-1,4-dioxaspiro[4.5]decane Ethylene glycolcyclohexanoneketalsingleloop 1,4- 1,4-Cyclohexanedione Monoethylene acetal 97% 1,4-Dioxaspiro[4.5]decan-8-one, 95+% 1,4-Dioxaspiro[4.5]decane-8-one- 4,4-(Ethylenebisoxy)cyclohexan-1-one 7,10-Dioxaspiro[5.4]decane-3-one Spiro[cyclohexane-1,2'-1,3-dioxolane]-4-one 1,4-Cyclohexanedione monoethylene acetal (1,4-Dioxaspiro(4 x 5)d Cyclohexanedione monoethyleneacetal 1,4-Dioxaspiro[4.5]decan-8-one,98% 1, 4 - cyclohexanol diketone glycol ketal 1,4-Dioxaspiro[4,5!decan-8-one, 97+% Cyclohexane-1,4-dione monoethylene acetal 99% 1,4-Dioxaspiro[4.5]decan-8-one/1,4-Cyclohexanedione Monoethylene Ketal 1,4-cyclohexanedione monoacetal 1 4-dioxiro[4.5]decan-8-one pharmaceutical intermediate Monoethylene glycol 1,4- cyclohexyl diketone 4-Cyclohexanedione Mo 1,4-cyclohexanedione monoethylene ketal 4746-97-8 1,4-Cyclohexanedione Monoethyleneketal > 1,4 cyclohexanedione monoethylene glycol acetophenone 1,4-Cyclohexanedione monoketal 1,4-Dioxaspiro[4.5]decan-8-one(4746-97-8) 1,4-Cyclohexanedione ethylene ketal 1,4-CYCLOHEXANEDIONE MONOETHYLENE ACETAL 1,4-CYCLOHEXANEDIONE MONOETHYLENE KETAL cyclohexanedione monoethylene ketal 1,4-Dioxaspiro[4.5]decan-8-one (6CI, 7CI, 8CI, 9CI, ACI) 1,4-CYCLOHEXANEDIONE MONOETHYLENE KETAL > 97% puriss for synthesis 1,4-Cyclohexanedione monoethylene cyclohexanedione monoacetal 4746-97-8 4740-97-8 C8H12O3 Acetals/Ketals/Ortho Esters Organic Building Blocks Oxygen Compounds